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991.
992.
993.
Venous ulcers are characterised by longstanding and recurrent loss of skin integrity. Once occurred, healing is slow and recurrence is high because of inappropriate conditions of the wound bed. This study involves 20 patients with chronic venous ulcers at least 6 weeks of duration treated with negative pressure wound therapy (NPWT). Patients underwent a radical debridement of all devitalised tissues in the first operation. After adequate haemostasis, silver-impregnated polyurethane foam was applied. Once the wounds were determined to be clean and adequate granulation tissue formation was achieved, split-thickness skin grafts were applied. Black polyurethane foam was applied over them. All wounds completely healed without the need for further debridement or regrafting. The mean number of silver-impregnated foam dressing changes prior to grafting was 2·9 (one to eight changes). The mean number of NPWT foam changes was 2·6 after skin grafting (two to five changes). Two patients who did not use conservative treatments for chronic venous insufficiency (CVI) after discharge from the hospital had recurrence of venous ulcers in the follow-up period. Application of NPWT provides quick wound-bed preparation and complete graft take in venous ulcer treatment. 相似文献
994.
Dalia Muhammed Al-Imam Hana Ibrahim Al-Sobayel 《Journal of Physical Therapy Science》2014,26(8):1193-1198
Burnout has been shown to be present in different health professions, but the prevalence
among physiotherapists working in an Arabian setting has not been established. [Purpose]
This study aimed to investigate the burnout levels of physiotherapists working in Saudi
Arabia and the association of burnout with work and organization-related factors.
[Subjects and Methods] A cross-sectional study was conducted at government hospitals in
Saudi Arabia. One hundred and nineteen Saudi physiotherapists were included. They
electronically completed a questionnaire that included the Maslach Burnout Inventory and
the Areas of Worklife Survey. [Results] Participants showed a moderate degree of burnout
as reflected by mean scores of the three subscales of the Maslach Burnout Inventory. The
majority of participants demonstrated moderate to high burnout levels across the three
subscales. A significant association was found between the exhaustion subscale and the
subspecialty in which participants worked. A strong association was found between workload
and exhaustion subscale scores. [Conclusion] This study was the first to explore burnout
and related factors among physiotherapists in an Arabian setting. A moderate degree of
burnout and associations of burnout with work and organizational factors were found. The
findings may help human resource planning and managing the physiotherapy services.Key words: Burnout, Health professional, Workplace 相似文献
995.
Dilek Solmaz Servet Akar Ozgul Soysal Yeşim Akkoc Gercek Can Vedat Gerdan Merih Birlik Fatos Onen Nurullah Akkoc 《Clinical rheumatology》2014,33(10):1475-1479
It is important to recognize inflammatory back pain (IBP) for an early diagnosis of ankylosing spondylitis (AS). Assessment of Spondyloarthritis International Society (ASAS) has recently published new criteria set for diagnosing IBP. In the present study, we evaluated the performance of the new ASAS IBP criteria and to compare the performance of IBP criteria sets in axial spondyloarthritis (axSpA) patients with and without radiographic sacroiliitis. The study sample included a total of 274 patients with a diagnosis of axSpA and 50 patients with a diagnosis of chronic (>3 months) mechanical back pain (MBP). A face-to-face interview by using a standardized questionnaire addressing all the components of IBP was performed. Data about HLA-B27 status and C-reactive protein levels were obtained from the patients’ charts. There were significantly more male patients (P?0.001) in the AS group (68.6 %) than in the non-radiographic axSpA group (29.6 %) and also than in the MBP group (37.5 %). Among the criteria sets, the Calin criteria showed the best sensitivity (91.2 %), and the Berlin criteria showed the best specificity (82.4 %) in differentiation of IBP from MBP. If the morning stiffness item of the Calin criteria was defined as lasting >30 min (Calin 30), the specificity improved (72.9 %), but at a price of loss in sensitivity (82.4 %). In this study, new ASAS criteria for IBP performed almost as good as but not better than the existing criteria sets. Performances of the criteria sets were quite comparable in the differentiation of IBP from MBP in patients with and without radiographic sacroiliitis. 相似文献
996.
997.
Serkan Dogan Ozden Piskin Dilek Solmaz Servet Akar Aytac Gulcu Faize Yuksel Volkan Cakır Ismail Sari Nurullah Akkoc Fatos Onen 《Rheumatology international》2014,34(8):1129-1138
The current clinical and laboratory parameters of Takayasu arteritis (TA) are insufficient for proper assessment of disease activity. The aims of this study were to investigate the markers of endothelial injury and repair, including circulating endothelial cell (CEC), circulating endothelial progenitor cell (CEPC) and vascular endothelial growth factor (VEGF), and evaluate their associations with disease activity in patients with TA. Thirty-two patients with TA and 30 healthy age- and sex-matched controls were included in this study. Disease activity was assessed in TA patients using various tools, including Kerr’s criteria, the Indian Takayasu’s Arteritis Scoring (ITAS2010) and physician’s global assessment (PGA). CECs and CEPCs were measured by flow cytometry, and VEGF was measured using an enzyme-linked immunosorbent assay. The CEC level was found to be higher in TA patients than in the healthy controls (HC) (p < 0.001). There was no significant difference in CEC level between the active and inactive patients, but its level was slightly correlated with C-reactive protein (CRP) level. CEPC and VEGF levels in TA patients with active disease were higher than those in the inactive patients and HC. CEPC and VEGF levels were positively correlated with ITAS-CRP and PGA scores. This study shows increased level of CEC in patients with TA. It also suggests that the CEPC and VEGF levels may be correlated with disease activity. 相似文献
998.
Mehmet Bayram Isa Dongel Ali Akbaş İsmail Benli Muhammed Emin Akkoyunlu Nur Dilek Bakan 《Lung》2014,192(1):197-203
Purpose
This study investigated the diagnostic accuracy of the serum biomarkers osteopontin and mesothelin in discriminating mesothelioma patients from those with other, benign conditions and whether levels of the biomarkers differed in subjects who had inhaled naturally occurring asbestos compared with a non-exposed control group.Methods
This cross-sectional study studied 24 subjects with mesothelioma, 279 subjects with pleural plaques, 123 “healthy exposed,” and 120 control subjects. The Kruskal–Wallis test was performed to compare mesothelin and osteopontin levels of the groups, and receiver operating characteristics curves were generated to determine diagnostic yields of both biomarkers. Multiple linear regression analyses were used to identify associated covariates with osteopontin and mesothelin levels.Results
Serum osteopontin and mesothelin levels were higher in mesothelioma than in benign asbestos-related diseases and healthy exposed subjects. Both biomarker levels were independently associated with mesothelioma, age and smoking pack years. Mesothelin levels were also associated with body mass index. The sensitivity and specificity of osteopontin in distinguishing mesothelioma from the three other groups were 75 and 86 %, respectively; those of mesothelin were 58 and 83 %, respectively. The sensitivity and specificity to discriminate mesothelioma from pleural plaques and healthy subjects were 93 and 73 %, respectively, if osteopontin and mesothelin levels were higher than their optimal cut off levels.Conclusions
The combination of serum osteopontin and mesothelin levels can help to distinguish mesothelioma from benign asbestos-related diseases and asbestos-exposed subjects. 相似文献999.
Serdar Soydinc Ibrahim Halil Turkbeyler Yavuz Pehlivan Gulcimen Soylu Mehmet Fatih Goktepe Muhammed Bilici Orhan Zengin Bunyamin Kisacik Ahmet Mesut Onat 《Inflammation》2014,37(1):100-106
The predictors for the development of cardiovascular diseases and peripheral arterial diseases in patients with systemic sclerosis (SSc) were not clearly established, and there is no specific study conducted to investigate the mean platelet volume (MPV) levels in SSc patients. Therefore, this study evaluates the MPV levels in SSc and possible relationship between SSc, its clinical features and activity/severity scores, and MPV. In total, 76 SSc patients (67 women and 9 men, mean age 50.44?±?13.21 years) diagnosed according to the classification criteria of the American College of Rheumatology and 45 healthy volunteers were enrolled into study. Data relating to anamnesis, physical examination, MPV, erythrocyte sedimentation rate, C-reactive protein levels, electrocardiography, echocardiography, high-resolution computerized tomography findings, complaints, and treatment processes were recorded into the database. Of the total cases, 17 had (22.3 %) cardiac involvement, 45 had gastrointestinal involvement (59.2 %), 47 had (61.8 %) lung involvement, 31 (32 %) had finger flexion deformity, and 27 (35.5 %) had digital ulcers at the fingertips. The mean MPV levels of SSc patients were significantly higher than those of the control group (p?=?0.008). The mean MPV levels of SSc patients with cardiac involvement, digital ulcers, and gangrene presence were significantly high, and lower in Ilomedin-receiving patients than in the Ilomedin naives (p?<?0.05). A negative relationship was discovered between the mean MPV levels, Valentini score, and Disease Severity Index of the patients with systemic sclerosis (p?=?0.006, r?=??0.310; p?=?0.047, r?=??0.229). MPV levels were significantly elevated in SSc patients and they were negatively correlated with disease activity scores. Increased MPV levels would be a predictive marker in the diagnosis of macrovascular and microvascular disease involvement in SSc patients. 相似文献
1000.
Ilgaz Cagatay Kose Mustafa Hizal Elif Gunay Bulut Eray Atli Fatma Bilge Ergen 《Surgical and radiologic anatomy : SRA》2014,36(5):503-505