全胃切除ρ形空肠代胃治疗胃癌64例报告

报告全胃切除ρ形空肠代胃治疗胃癌６４例。术后无吻合口瘘与手术死亡，无返流性食管炎和倾倒综合征，生存质量满意。术后１、３、５年生存率分别为７１．８％、４２．２％和３４．４％。本组结果表明：此种改良后的ρ形空肠代胃、空肠原位间置术式，安全、简便、省时，使常见的手术并发症和远期后遗症均可得到较好预防和纠正，术后生存质量高，是一种满意的代胃术。     

Studies on monoclonal anti-isotypic and anti-idiotypic antibodies against leukemia and myeloma: IV modulation of membrane fluidity of leukemic cell lines and tonsillar cell stimulated with McAbs

Summary In this study the technique of labelling the cell membrane with DPH fluorescence polarization was used to observe the membrane fluidity of B lymphocytic cell lines and tonsillar cells from healthy persons; the modulation effect on membrane-fluidity induced by McAbs against isotypic and idiotypic determinants of IgM from patients with leukemia was studied as well. The expression of the corresponding isotypic and idiotypic determinants of IgM on the cell membrane was determined. The results show that the membrane fluidity of leukemic cell lines is remarkably higher than that of tonsillar cells from healthy persons, and McAbs against isotypic determinants of leukemic IgM can enhance the membrane fluidity of all kinds of cells mentioned above. However, the anti-idiotypic monoclonal antibody increased only the membrane fluidity of leukemic cell lines. These results indicated that there was a close relationship between the effect of McAbs on cell membrane fluidity and the expression of corresponding isotypic and idiotypic determinants of IgM on the cell membrane.     

Precision of mean transit time measurements in 99Tcm-DTPA renal scintigraphy: a Monte Carlo study.

The precision of renal mean transit time (MTT) measurements by 99Tcm-DTPA scintigraphy was studied by a Monte Carlo procedure. Data were obtained from twenty mild essential hypertensives with normal renal function. An ensemble of equivalent data sequences was constructed for each renal time-activity curve (TAC), assuming the dominant noise in the data to be Poisson in character. TACS were deconvolved by the matrix method and MTT was inferred from retention functions by a procedure entailing a nonlinear least-squares minimization. For every ensemble of data sequences a distribution of MTTs was generated. The population-averaged coefficients of variation for these distributions were 1.6% and 2.6%, for whole-kidney and cortical data, respectively. We conclude that the precision of MTT determination from clinical data is comparable to that from simulated data. MTT measurements may be useful for detecting functional changes in individual kidneys following an intervention such as angiotensin-converting-enzyme inhibition.     

CO and particle pollution of indoor air in Beijing and its elemental analysis

Three representative types of houses in Beijing were selected and, in each type, smoking and nonsmoking households were compared, IP, RP, and CO concentrations in the living room and kitchen were monitored during each season, and the level of COHb in the heads of the households were measured. The study showed that indoor air pollution was rather severe, especially during winter, when particulate concentrations markedly exceeded the standard and CO concentration was as high as 47 ppm. Indoor air pollution was closely related to the type of house, particularly to the mode of heating. In houses, of the same type, pollution improved greatly after central heating facilities were installed. Analysis of 30 elements revealed that pollution was typically caused by coal burning, aggravated by dusty wind, but high indoor Pb levels were probably due to the use of LPG for cooking. In our study the effect of cigarette smoking was sometimes masked by the severe indoor pollution.     

Segmental fixation with U-shaped rod in the treatment of spondylolisthesis

Summary From 1987 to 1990 the authors treated 20 cases of spondylolisthesis by an improved operative procedure including excision of the medial part of the superior articular processes of the slipped vertebra, excision of the soft tissue between the ununited isthmi, and excision of the ligamentum flavum between the intervertebral space above the slipped segment. In some instances the lower portion of the lamina over the slipped vertebra should be resected. A U-shaped rod was used to hold sublaminar fixation of two segments above and below the slipped vertebra, with the slipped vertebra spared. Utilizing the U-shaped rod as support, bone strips were placed along the lateral and anterior sides of the rod to bridge the gap between the laminae of the displaced vertebra. Other bone grafts were focused on the facet joints. The patients were allowed ambulation early postoperatively. 19 cases could be evaluated at preliminary follow-up. All showed satisfactory results.     

胃癌腹腔脱落细胞检查及临床意义

腹膜转移是胃癌常见的转移形式。为在肉眼可见转移前发现亚临床的转移现象,自1981年3月至1982年4月,我们共对胃癌病人142例进行了腹腔脱落细胞检查及临床随诊,发现有腹腔脱落细胞阳性者76例(53.5％)。5年随诊结果发现,腹腔脱落细胞阳性者无一例生存>3年;而腹腔脱落细胞阴性的66例中生存5年者有11例。可见,腹腔脱落细胞检查,对胃癌的诊断,治疗和预后判断有一定价值。