全文获取类型
收费全文 | 207506篇 |
免费 | 40853篇 |
国内免费 | 10134篇 |
专业分类
耳鼻咽喉 | 3363篇 |
儿科学 | 3554篇 |
妇产科学 | 3369篇 |
基础医学 | 15745篇 |
口腔科学 | 6912篇 |
临床医学 | 40923篇 |
内科学 | 40358篇 |
皮肤病学 | 4369篇 |
神经病学 | 17896篇 |
特种医学 | 7701篇 |
外国民族医学 | 78篇 |
外科学 | 28919篇 |
综合类 | 20930篇 |
现状与发展 | 81篇 |
一般理论 | 6篇 |
预防医学 | 20626篇 |
眼科学 | 5388篇 |
药学 | 12995篇 |
96篇 | |
中国医学 | 7139篇 |
肿瘤学 | 18045篇 |
出版年
2024年 | 860篇 |
2023年 | 6648篇 |
2022年 | 5114篇 |
2021年 | 8926篇 |
2020年 | 9878篇 |
2019年 | 5891篇 |
2018年 | 10855篇 |
2017年 | 10893篇 |
2016年 | 11291篇 |
2015年 | 13249篇 |
2014年 | 16846篇 |
2013年 | 17666篇 |
2012年 | 11919篇 |
2011年 | 12541篇 |
2010年 | 12487篇 |
2009年 | 13536篇 |
2008年 | 9227篇 |
2007年 | 8073篇 |
2006年 | 9065篇 |
2005年 | 7704篇 |
2004年 | 5049篇 |
2003年 | 4441篇 |
2002年 | 3876篇 |
2001年 | 4438篇 |
2000年 | 3921篇 |
1999年 | 4640篇 |
1998年 | 4028篇 |
1997年 | 3887篇 |
1996年 | 3483篇 |
1995年 | 3142篇 |
1994年 | 2335篇 |
1993年 | 1689篇 |
1992年 | 1719篇 |
1991年 | 1414篇 |
1990年 | 1163篇 |
1989年 | 1129篇 |
1988年 | 1011篇 |
1987年 | 814篇 |
1986年 | 741篇 |
1985年 | 582篇 |
1984年 | 379篇 |
1983年 | 408篇 |
1982年 | 287篇 |
1981年 | 264篇 |
1980年 | 163篇 |
1979年 | 114篇 |
1978年 | 119篇 |
1977年 | 114篇 |
1976年 | 83篇 |
1974年 | 71篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
51.
Tianying Yang Jiawei Li Yichen Jia Chunchen Yang Ruirui Sang Tongyu Zhu Ming Xu Ruiming Rong Cheng Yang 《Translational andrology and urology》2021,10(1):204
BackgroundIn the field of transplantation, inducing immune tolerance in recipients is of great importance. Blocking co-stimulatory molecule using anti-CD28 antibody could induce tolerance in a rat kidney transplantation model. Myeloid-derived suppressor cells (MDSCs) reveals strong immune suppressive abilities in kidney transplantation. Here we analyzed key genes of MDSCs leading to transplant tolerance in this model.MethodsMicroarray data of rat gene expression profiles under accession number in the Gene Expression Omnibus (GEO) database were analyzed. Running the LIMMA package in R language, the differentially expressed genes (DEGs) were found. Enrichment analysis of the DEGs was conducted in the Database for Annotation, Visualization and Integrated Discovery (DAVID) database to explore gene ontology (GO) annotation and their Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. Their protein-protein interactions (PPIs) were provided by STRING database and was visualized in Cytoscape. Hub genes were carried out by CytoHubba.ResultsThree hundred and thirty-eight DEGs were exported, including 27 upregulated and 311 downregulated genes. The functions and KEGG pathways of the DEGs were assessed and the PPI network was constructed based on the string interactions of the DEGs. The network was visualized in Cytoscape; the entire PPI network consisted of 192 nodes and 469 edges. Zap70, Cdc42, Stat1, Stat4, Ccl5 and Cxcr3 were among the hub genes.ConclusionsThese key genes, corresponding proteins and their functions may provide valuable background for both basic and clinical research and could be the direction of future studies in immune tolerance, especially those examining immunocyte-induced tolerance. GSE28545相似文献
52.
53.
Jamaal L. Benjamin MD PhD Rebecca Dennis DO Stacy White Jr MD David Munson MD Sudha A. Anupindi MD Maciej Piskunowicz MD Kassa Darge MD PhD Ami Gokli MD Misun Hwang MD 《Journal of ultrasound in medicine》2020,39(5):1031-1036
Bowel diseases of prematurity, including necrotizing enterocolitis, are dreaded ailments of neonates. Early diagnosis is difficult, with clinical and radiographic findings often inconclusive. We present a novel use of contrast-enhanced ultrasound in detection of pediatric bowel disease. Early identification of compromised blood flow or an at-risk bowel can be quantitatively detected and monitored. This ability has implications for guidance of emerging therapies, allowing targeting of inflammation. These findings represent an advancement in detection of bowel disease in neonates. 相似文献
54.
55.
目的本研究立足于项目组前期研究的成果上,积极探索吉林辽宁两省目标设置水平的差异,并进一步探究受目标设置影响下的工作落实结果情况,探讨产生差异的原因。
方法以系统穷尽的方式收集吉林辽宁两省2000至2017年有关目标与工作落实情况的指标,利用Spearman相关和线性回归分析吉林辽宁两省目标设置对于突发应急工作落实情况的影响。
结果吉林辽宁两省突发应急领域的目标设置水平与工作落实情况总体均呈现上升趋势,截至2017年,吉林目标设置水平与工作落实情况分别为46%与60%,辽宁为60%与53.3%,且目标设置水平与工作落实呈正相关。
结论有公众需要为依据且定量可考的目标设置对于工作落实、推进、完善具有积极的正反馈作用,建立科学量化的突发应急目标设置评价体系是适宜可行的。 相似文献
56.
57.
Maaike van Gerwen MD Naomi Alpert MS Raja Flores MD Emanuela Taioli MD PhD 《American journal of industrial medicine》2020,63(2):115-120
The association between asbestos exposure, mainly in occupational settings, and malignant mesothelioma has been well established; this has prompted several countries to establish mesothelioma epidemiologic surveillance programs often at the request of national agencies. This review compares currently existing mesothelioma registries worldwide to develop a concept model for a US real-time case capture mesothelioma registry. Five countries were identified with a mesothelioma specific registry, including Italy, France, UK, Australia, and South Korea. All, except the UK, used interviews to collect exposure data. Linkage with the national death index was available or was in future plans for all registries. The registries have limited information on treatment, quality of life, and other patient-centered outcomes such as symptoms and pain management. To thoroughly collect exposure data, “real-time” enrollment is preferable; to maximize the capture of mesothelioma cases, optimal coverage, and a simplified consent process are needed. 相似文献
58.
59.
Chie Teramoto PHN RN MS Satoko Nagata PhD PHN RN Reiko Okamoto PhD PHN RN Ruriko Suzuki PHN RN MS Emiko Kishi PhD PHN RN Michie Nomura DSN PHN RN Noriko Jojima PHN RN MS Masumi Nishida PhD PHN RN Keiko Koide PhD PHN RN Emiko Kusano PhD PHN RN Saori Iwamoto PhD PHN RN Sachiyo Murashima PhD PHN RN 《Public health nursing (Boston, Mass.)》2015,32(6):654-661
60.