改变产妇体位矫正胎儿方位的临床效果

目的:探讨产程中改变产妇体位以矫正胎位。方法:选择临产至宫口开全经B超及内诊检查为枕后位的初产妇200例,随机分为观察组与对照组各100例,在产程中指导观察组产妇取侧俯卧位,利用胎儿重力、羊水浮力、子宫间歇性收缩的合力作用,使胎头下降时逐渐从枕后位转至枕前位娩出,并与对照组比较。结果:观察组91例(91％)胎儿由枕后位转至枕前位经阴道分娩,剖宫产9例(9％);对照组经阴道分娩仅16例(16％),剖宫产84例(84％)。两组比较差异有显著性(P<0.01)。结论:在产程中指导产妇取侧俯卧位,用以矫正胎位不正是降低难产发生率的有效方法。     

Detection of superior mesenteric vein thrombosis following splenectomy using real-time and Doppler sonography

Superior mesenteric vein thrombosis after splenectomy is very rare. In the case described of a patient presenting with acute abdominal pain the diagnosis was made primarily by real-time and Doppler ultrasonography. This reduced the time elapsing before it was recognized that angiography and subsequent thrombectomy were indicated.     

The risk of post-operative infection after reamed intramedullary locked nailing of tibial fractures. A review of 730 cases

Summary 730 consecutive acute reamed intramedullary locked nailing of tibial fractures were studied, according to Gustilo’s classification of soft tissue lesions for the open fractures. There is a significant increase of post-operative infection rate if the tibial fracture is open, and the relative risk increases with the severity of soft tissue lesions. The comparison of these figures with those of other methods of treatment and the mechanical and clinical advantages of nailing leads us to propose this method for treatment of grade I, II and IIIa open fractures, while external the fixator seems better adapted for IIIb and c open fractures. European Bone and Joint Infection Society Meeting, München, Germany, October 7–9, 1993     

交链孢酚单甲醚在大鼠小鼠体内的分布

对食管癌高发区粮食中分离的互隔交链孢霉的毒素交链孢酚单甲醚(AME)在大鼠、小鼠体内的分布进行研究。给动物腹腔内注射氚标记的交链孢酚单甲醚(~3H-AME),然后在不同时间测各脏器的放射性。结果表明:在所测9个脏器中,2h肝脏含量最高,食管下段在大小鼠分别居第四和第三。但大小鼠分别在72、24h则以食管下段最高,说明AME及其代谢物在此清除较慢,即对其有较高的亲和力。     

Formoterol and salbutamol inhibit bradykinin- and histamine-induced airway microvascular leakage in guinea-pig.

1. The effects of the beta 2-adrenoceptor agonists, salbutamol and formoterol, on the increase of microvascular permeability induced by histamine or bradykinin in guinea-pig airways have been studied in vivo. Extravasation of intravenously injected Evans blue dye was used as an index of permeability. The effects of salbutamol and formoterol on the increase in pulmonary airway resistance induced by histamine or bradykinin have also been studied. 2. The increase in pulmonary airway resistance induced by histamine or bradykinin was totally inhibited by salbutamol and formoterol. The ED50 of the two mediators were 0.59 +/- 0.21 (n = 5) and 0.20 +/- 0.14 (n = 5) micrograms kg-1 respectively for salbutamol, and 0.13 +/- 0.12 (n = 6) and 0.02 +/- 0.01 (n = 6) micrograms kg-1 respectively for formoterol. 3. Salbutamol (10 and 30 micrograms kg-1) and formoterol (1 and 10 micrograms kg-1) inhibited the increase of microvascular permeability induced by histamine (30 micrograms kg-1) in the guinea-pig airways. The inhibitory effect was predominant in the trachea and the main bronchi, with a maximum inhibition of 20 to 50%. The two drugs had little or no inhibitory effect on the other structures studied, viz. nasal mucosa, larynx, proximal and distal intrapulmonary airways. 4. Salbutamol and formoterol (1 and 10 micrograms kg-1) abolished the increase in microvascular permeability induced by bradykinin (0.3 micrograms kg-1). This inhibitory effect of two beta-adrenoceptor stimulants was predominant in the trachea and the nasal mucosa where it was observed with 1 microgram kg-1 of the beta-adrenoceptor agonists.(ABSTRACT TRUNCATED AT 250 WORDS)     

我国原料药产业的发展策略

经济全球化进程的加快，中国加入世贸组织，为我国医药产业国际化发展带来了机遇。     

徐元庚老中医治疗肛肠疾病学术经验简介

徐元庚老中医是我院肛肠科奠基人之一,徐老年逾花甲,幼年攻读中医典籍,博采众长,徐老积40余年丰富临床经验对肛肠疾病治疗确有独到之处,发表论文40余篇,并编著《痔瘘疾病临床指南》一书。现就笔者往昔随师学习的点滴体会简述如下:1 熟读经旨,著书立说徐老出身于中医世家,幼承庭训,勤奋研读经典,深究其理,对《内经》、《伤寒》、《金匮》至今仍能背诵如流。在治学方面,主张志于医者,在熟读经典,而后逐步参悟经旨,阅读诸家医集,抱着实事求是的客观态度,掌握取长舍短,去粗存精的学习方法,以防食古不化,或断章取     

一种基于μ子进行核材料探测成像的模拟系统

宇宙射线斗子成像检测技术具有穿透力强、对高Z材料敏感等特点，特别适合检测特殊核材料，是监控核材料走私的有效方式之一。在搭建μ子成像检测硬件系统的同时，我们开发了一套针对实际硬件系统的模拟系统，并利用该系统开展斗子成像方法的研究。本文将介绍该模拟系统的有关情况，并给出利用该系统得到的仿真结果。相信这一工作将对实际宇宙射线μ子成像系统的设计给出指导意见。     

顺糖氨铂(Ⅱ)的合成

以氯铂酸钾为原料，经硫酸氨铂(Ⅱ)中间体制得抗肿瘤药物顺糖氨铂(Ⅱ)，操作简便，总收率46．1％。