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991.
992.
Kantarci F Ozpeynirci Y Unlu M Gulsen F Ozbayrak M Botanlioglu H Inan M Mihmanli I Cantasdemir M 《European radiology》2012,22(6):1350-1356
European Radiology - To investigate the utility of ultrasound cross-sectional area (CSA) measurements for diagnosing acetabular labral (AL) tears. The study included qualitative/quantitative... 相似文献
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Huseyin Sen Suleyman Deniz A. Erturk Yedekci Gokhan Inangil Tuba Muftuoglu Aptullah Haholu 《Renal failure》2014,36(10):1570-1574
Background: We investigated the anti-inflammatory and protective effects of concomitant use of dexpanthenol (DXP) and N-acetylcysteine (NAC) induced ischemia/reperfusion (I/R) injury of kidney. Methods: Forty rats were randomly divided into 5 groups. In all groups except for Group 1(Sham), renal arteries bilaterally occluded with vascular clamp for IR injury. Group 1(Sham), received a single dose of 10?mL/kg isotonic saline daily by intraperitoneal (IP) injection for three days. Group 2(IR), received a single dose of 10?mL/kg isotonic saline daily by IP injection for three days. Group 3(IR?+?NAC), received 300?mg/kg NAC daily by IP injection for three days. Group 4(IR?+?DXP), received 500?mg/kg DXP daily by IP injection for three days. Group 5(IR?+?NAC?+?DXP), received 500?mg/kg DXP and 300?mg/kg NAC daily by IP injection for three days. Serum urea (BUN), creatinine (Cr) and neutrophil gelatinase-associated lipocalin (NGAL, lipocalin 2, siderocalin) levels were measured as kidney function tests. TNF-α levels were measured as inflammatory marker. Tissue sections were evaluated histopathologically under light microscopy. Results: IR?+?NAC?+?DXP group received both NAC and DXP before induction of renal I/R and as the biochemical and histopathological data revealed the results of the IR?+?NAC?+?DXP group and sham group were similar. Biochemically and histopathologically, combined use of NAC and DXP has better results when each of them used alone. Conclusion: We concluded that concomitant use of DXP and NAC plays a major role against I/R injury and may be useful in acute treatment of I/R induced renal failure. 相似文献
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Alper Otunctemur Murat Dursun Emin Ozbek Suleyman Sahin Huseyin Besiroglu Ismail Koklu Mustafa Erkoc Eyyup Danis Muammer Bozkurt 《International urology and nephrology》2014,46(8):1501-1505
Aim
In the present study, we prospectively collected data from pre- to postmenopausal women with or without metabolic syndrome (MetS) and evaluated the impact of MetS on stress urinary incontinence (SUI) in women.Material and methods
The women divided into four equal groups: premenopausal with and without MetS; postmenopausal with and without MetS. There were 100 women in each group. We assessed the women for SUI at gynecologic position and we determined cough stress test. MetS was defined according to the criteria established in 2005 by the NCEP/ATP III.Results
Mean age was 48.52 ± 8.16 in women with MetS and 48.81 ± 8.31 in women without MetS. SUI was found more often in both pre- and postmenopausal women with MetS (p = 0.001 and p < 0.001). It seems that postmenopausal women have more SUI than premenopausal women with MetS. We also evaluated the association between five components of MetS and SUI. Just, higher fasting glucose levels and waist circumference were significantly associated with SUI (p < 0.05).Conclusion
Our study shows that SUI is more prevalent in pre- and postmenopausal women with the MetS. SUI can be prevented with lifestyle changes for MetS. Multicenter studies with larger series and molecular studies are needed to determine the impact of the MetS on SUI. 相似文献998.
Sedat Belli Huseyin Ozgur Aytac Erdal Karagulle Hakan Yabanoglu Fazilet Kayaselcuk Sedat Yildirim 《International surgery》2014,99(6):691-698
Colorectal primary signet ring cell carcinoma (PSRCCR) is a rare entity with a dismal prognosis, mainly because of delayed diagnosis. The objective of this study was to investigate the clinicopathologic features and prognostic factors for PSRCCR. This is a retrospective study including the data of 22 patients with PSRCCR who underwent surgery. Patients were categorized by age, sex, tumor site, and stage. Fifteen patients were male. Median age was 40 years. Sites for metastases were lymph nodes (86.4%), peritoneum (40.9%), and liver (9.1%). Most of the patients (91%) had stage III or IV tumors. The rates of curative and palliative resections performed were equal. Mean overall survival and mean progression-free survival times were found to be 33.3 ± 7.1 months (95% confidence interval, 19.4–47.2 months) and 11.8 ± 3.5 months (95% confidence interval, 4.9–18.7 months), respectively. It was concluded that site of the tumor, presence of bowel obstruction, peritoneum and lung metastases, adjacent organ infiltration, TNM stage, and efficiency of surgery have significant effects on survival. All in all, these aggressive tumors are generally diagnosed at advanced stages. Depending on the situation, survival is shorter. A high degree of vigilance is required for these patients to avoid the negative impact of late diagnosis on survival.Key words: Signet ring cell, Colorectal cancer, Histopathology, SurvivalPrimary signet ring cell carcinoma is a tumor most commonly located in the stomach, and less frequently in the breast, gallbladder, bladder, and pancreas.1 Primary signet ring cell carcinoma of the colon and rectum (PSRCCR) is a rare entity, with a reported incidence of less than 1%.2 It has a markedly poor prognosis.3 Because symptoms often develop late, it is usually diagnosed at an advanced stage.4 Furthermore, it typically appears in young adults.5Macroscopically, PSRCCR shows the characteristic appearance of linitis plastica, as a shrunken, rigid structure.1–5 Histologically, the neoplastic cells resemble signet rings because they contain abundant intracytoplasmic mucin, which pushes the nuclei to the periphery.1–5 The presence of mucus secretion in microscopic examinations of the tumor is one of the most important parameters determining the biologic behavior of colorectal carcinomas; other factors are age, sex, tumor location, tumor diameter, grade, stage, lymphatic and vascular invasion, periserosal overgrowth, and distant metastasis.6,7So far, only a limited number of case reports have been published on this subject. Most publications have reported on a small number of patients and have presented controversial results. The objective of this study was to investigate the characteristic clinicopathologic features of colorectal signet ring cell carcinomas and the parameters affecting prognosis within our patient group. 相似文献
999.
Huseyin Yilmaz Husnu Alptekin Fahrettin Acar Akin Calisir Mustafa Sahin 《Obesity surgery》2014,24(1):123-127
Background
Modifications of minimally invasive laparoscopic cholecystectomy have been achieved, including single-incision laparoscopic cholecystectomy (SILC). In the current literature, the effects of high body mass index (BMI) on the results of the surgical therapy have not been sufficiently investigated after SILC. We evaluated perioperative outcomes and postoperative complications of overweight patients who underwent SILC.Methods
Two hundred two patients who underwent SILC were retrospectively evaluated. The data included demographics and outcomes such as postoperative complications and postoperative hospitalization were obtained. For the outcome analyses, patients were divided into two group according to their BMI (<30 vs ≥30 kg/m2).Results
Of the 202 patients, 157 patients were in normal weight group and 45 patients were in overweight group. Mean operative time was 31.67?±?6.4 min in overweight group and 26.6?±?5.3 min in normal weight group. The wound infection rate for overweight and normal weight patients was 13.3 and 7.6 %, respectively. Eleven of the 202 patients (5.4 %) experienced port-site hernia (PSH).Conclusions
This retrospective study comparing overweight and normal weight patient in SILC demonstrates that SILC is associated with the prolonged operative time, high additional port requirement, and increased wound complication rate. PSH occurrence rate was high after SILC irrespective of the body weight. 相似文献1000.