全文获取类型
收费全文 | 2910篇 |
免费 | 149篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 49篇 |
儿科学 | 226篇 |
妇产科学 | 45篇 |
基础医学 | 297篇 |
口腔科学 | 113篇 |
临床医学 | 213篇 |
内科学 | 666篇 |
皮肤病学 | 80篇 |
神经病学 | 150篇 |
特种医学 | 104篇 |
外科学 | 535篇 |
综合类 | 46篇 |
预防医学 | 91篇 |
眼科学 | 56篇 |
药学 | 210篇 |
中国医学 | 13篇 |
肿瘤学 | 183篇 |
出版年
2023年 | 25篇 |
2022年 | 51篇 |
2021年 | 95篇 |
2020年 | 59篇 |
2019年 | 96篇 |
2018年 | 102篇 |
2017年 | 91篇 |
2016年 | 83篇 |
2015年 | 87篇 |
2014年 | 123篇 |
2013年 | 154篇 |
2012年 | 237篇 |
2011年 | 225篇 |
2010年 | 133篇 |
2009年 | 111篇 |
2008年 | 183篇 |
2007年 | 167篇 |
2006年 | 163篇 |
2005年 | 158篇 |
2004年 | 118篇 |
2003年 | 103篇 |
2002年 | 81篇 |
2001年 | 60篇 |
2000年 | 52篇 |
1999年 | 45篇 |
1998年 | 24篇 |
1997年 | 13篇 |
1996年 | 11篇 |
1995年 | 10篇 |
1994年 | 5篇 |
1993年 | 10篇 |
1992年 | 15篇 |
1991年 | 18篇 |
1990年 | 11篇 |
1989年 | 15篇 |
1988年 | 25篇 |
1987年 | 8篇 |
1986年 | 14篇 |
1985年 | 12篇 |
1984年 | 7篇 |
1983年 | 5篇 |
1982年 | 6篇 |
1981年 | 7篇 |
1980年 | 4篇 |
1975年 | 8篇 |
1974年 | 12篇 |
1973年 | 7篇 |
1970年 | 5篇 |
1969年 | 4篇 |
1968年 | 4篇 |
排序方式: 共有3077条查询结果,搜索用时 15 毫秒
31.
32.
STUDY DESIGN: Seventy-five surgically excised prolapsed intervertebral discs were histopathologically evaluated. Fifteen prospective normal cadaveric discs were used as control specimens. OBJECTIVE: To compare the morphologic features between the prolapsed and normal discs. SUMMARY OF BACKGROUND DATA: The histologic criteria were edge neovascularization of the fibrocartilage, chondrocyte cloning, fibrillation with fraying, and granular change. METHODS: Sections stained with hematoxylin and eosin, Van Gieson's, and toluidine blue were studied. The presence or absence of edge neovascularization was noted. The other criteria were graded based on a semiquantitative scoring system. RESULTS: Edge neovascularization was observed in 56% of the discs in the test group and in none of the control specimens. Fibrillation with fraying was the most significant finding in the test group (P < 0.001). Although the mean grades were higher in the test group, they did not predict the presence of edge neovascularization. CONCLUSIONS: Edge neovascularization was the most significant finding to confirm disc prolapse. Fibrillation with fraying, was observed more frequently in prolapsed intervertebral discs and the grades of fibrillation with fraying, chondrocyte cloning, and granular change were significantly higher in the test group. Pathologists can usually agree on the presence or absence of a particular histologic characteristic but are rarely consistent when they estimate the degree. Simple, reproducible agreed-on criteria are needed before semiquantitative evaluations become reliable. 相似文献
33.
B D Shenoy N Udupa R Kamath P U Devi 《Indian journal of physiology and pharmacology》1999,43(2):259-262
Anti-tumor efficacy of Centchroman formulated as niosomes and gel implant was evaluated in Swiss albino mice bearing Ehrlich ascites carcinoma at 10 mg/kg body weight dose given subcutaneously. Median day of death, percentage increase in host life span and changes in body weight were studied. Centchroman significantly (P < 0.05) increased the median day of death both in free and formulated systems. Also, injectable formulations exhibited a significant (P < 0.05) increase in host life span compared to free drug, hence, enhanced anti-tumor efficacy against Ehrlich ascites carcinoma. 相似文献
34.
35.
Morphea is an inflammatory cutaneous disease that can be mistaken for a soft-tissue neoplasm. The authors report two cases of morphea that were resected surgically before the histological diagnosis of morphea was rendered. One of the patients had a recurrence of morphea around her large surgical scar. They present these cases to alert surgeons to the pitfall of inappropriate surgical treatment of an inflammatory condition. 相似文献
36.
Foetuses born to mothers with gestational diabetes are at increased risk of developing respiratory distress, foetal macrosomia, foetal anomalies and platelet hyperaggregability. High blood glucose level induces oxidative stress and decreases antioxidant defences. The present study discusses the possibility of lipid peroxidation and protein oxidation in both maternal and foetal erythrocytes as an indicator of oxygen radical activity. The level of lipid peroxidation and protein oxidation in erythrocytes was estimated in 20 mothers with gestational diabetes and their newborns. The maternal age varied between 19 and 42 y and foetal age ranged between 34 and 39 weeks. The proteolytic activities in the erythrocyte lysates obtained from mothers with gestational diabetes and their newborns were significantly greater [(mean ± SD) 24.41 ± 9.05 and 16.70 ± 3.36μM of amino groups/g haemoglobin, n = 20, respectively] than those from control group (10.18 ± 4.84 and 14.64 ± 6.21 μM amino groups/g haemoglobin, n = 15, respectively; p < 0:05 in both cases). Similarly erythrocyte malondialdehyde levels were significantly elevated in babies born to mothers with gestational diabetes (10.11 ±2.21 nM/g haemoglobin) when compared to controls (6.8 ± 3.75 nM/g haemoglobin) (p < 0:05). In the erythrocytes of mothers with gestational diabetes, malondialdehyde levels correlated significantly with glycated haemoglobin levels (p < 0:01). The results of this study indicate that the oxidative stress induced by gestational diabetes manifests as increased lipid peroxidation and protein oxidative damage in the erythrocytes of both mothers with gestational diabetes and their newborn infants. 相似文献
37.
Mahesh Chandra Hedge Panduranga M. Kamath Suja Shreedharan Naveen Kumar Dannana Ravikumar M. Raju 《Indian journal of otolaryngology and head and neck surgery》2006,58(1):31-34
The efficacy of supravital staining in the detection of malignancies in oro and oropharyngeal lesions and its role in the
detection of malignant changes in premalignant lesions were studied. This prospective study comprises 90 cases of clinically
suspicious lesions and it was done over a period of 3 years. Most of the patients had multiple risk factors for the development
of malignancy. All underwent staining with a modified solution of 1% toluidine blue (TB). In our study the overall sensitivity
was 97.29% and the specificity was 62.5%. 相似文献
38.
Girish K Mayur PM Saravanan ES Janakiramaiah N Gangadhar BN Subbakrishna DK Rao GS 《The journal of ECT》2000,16(3):258-262
Formula methods of estimating seizure threshold in bilateral electroconvulsive therapy (ECT) have been successful in 75% (at the first ECT) and 80% (at the sixth ECT) of treatments (Gangadhar et al., 1998). This study showed the same results for unilateral (UL) ECT patients. Its aim was to compare formula and titration methods for threshold determination. The seizure threshold (dependent variable) was determined by the titration method used at the first ECT in consecutive consenting patients (n = 80) prescribed UL ECT under general anesthesia. The independent variables were age, gender, diagnosis, illness severity, concurrent drugs, head circumference, and inion-nasion distance. Forward, step-wise, linear regression analysis showed age as the only significant predictor of seizure threshold (15% of variance). A formula based on regression analysis was prospectively applied in an independent sample (n = 30) of patients receiving UL ECT using the titration method for threshold determination. The results calculated a higher threshold than the actual threshold used in 14 patients, a threshold level in 8 patients, and below threshold in 8 patients. Formula-based estimates would have been successful in 22 (73%) patients, but the majority of them would have received higher than the recommended stimulus dose. Titration is the method preferred for clinical use. However, if a patient's doctor wishes to use the formula-based method, he or she should do so with specific considerations. 相似文献
39.
40.