收费全文 | 2972篇 |
免费 | 186篇 |
国内免费 | 10篇 |
耳鼻咽喉 | 29篇 |
儿科学 | 176篇 |
妇产科学 | 40篇 |
基础医学 | 278篇 |
口腔科学 | 101篇 |
临床医学 | 216篇 |
内科学 | 651篇 |
皮肤病学 | 64篇 |
神经病学 | 103篇 |
特种医学 | 102篇 |
外科学 | 537篇 |
综合类 | 72篇 |
一般理论 | 1篇 |
预防医学 | 105篇 |
眼科学 | 207篇 |
药学 | 301篇 |
中国医学 | 5篇 |
肿瘤学 | 180篇 |
2023年 | 37篇 |
2022年 | 100篇 |
2021年 | 166篇 |
2020年 | 88篇 |
2019年 | 109篇 |
2018年 | 134篇 |
2017年 | 75篇 |
2016年 | 118篇 |
2015年 | 103篇 |
2014年 | 149篇 |
2013年 | 183篇 |
2012年 | 277篇 |
2011年 | 266篇 |
2010年 | 129篇 |
2009年 | 94篇 |
2008年 | 151篇 |
2007年 | 136篇 |
2006年 | 124篇 |
2005年 | 107篇 |
2004年 | 91篇 |
2003年 | 76篇 |
2002年 | 52篇 |
2001年 | 27篇 |
2000年 | 28篇 |
1999年 | 30篇 |
1998年 | 18篇 |
1997年 | 9篇 |
1996年 | 7篇 |
1994年 | 14篇 |
1992年 | 22篇 |
1991年 | 19篇 |
1990年 | 17篇 |
1989年 | 23篇 |
1988年 | 21篇 |
1987年 | 12篇 |
1986年 | 16篇 |
1985年 | 9篇 |
1984年 | 6篇 |
1982年 | 9篇 |
1981年 | 6篇 |
1980年 | 9篇 |
1979年 | 13篇 |
1978年 | 7篇 |
1977年 | 7篇 |
1976年 | 6篇 |
1975年 | 7篇 |
1974年 | 9篇 |
1971年 | 6篇 |
1970年 | 6篇 |
1969年 | 9篇 |
Background and Objective
Low‐level laser (light) therapy (LLLT) is a noninvasive, nonthermal approach to disorders requiring reduction of pain and inflammation and stimulation of healing and tissue regeneration. Within the last decade, LLLT started being investigated as an adjuvant to liposuction, for noninvasive body contouring, reduction of cellulite, and improvement of blood lipid profile. LLLT may also aid autologous fat transfer procedures by enhancing the viability of adipocytes. However the underlying mechanism of actions for such effects still seems to be unclear. It is important, therefore, to understand the potential efficacy and proposed mechanism of actions of this new procedure for fat reduction.Materials and Methods
A review of the literature associated with applications of LLLT related to fat layer reduction was performed to evaluate the findings from pre‐clinical and clinical studies with respect to the mechanism of action, efficacy, and safety.Results
The studies as of today suggest that LLLT has a potential to be used in fat and cellulite reduction as well as in improvement of blood lipid profile without any significant side effects. One of the main proposed mechanism of actions is based upon production of transient pores in adipocytes, allowing lipids to leak out. Another is through activation of the complement cascade which could cause induction of adipocyte apoptosis and subsequent release of lipids.Conclusion
Although the present studies have demonstrated safety and efficacy of LLLT in fat layer reduction, studies demonstrating the efficacy of LLLT as a stand‐alone procedure are still inadequate. Moreover, further studies are necessary to identify the mechanism of action. Lasers Surg. Med. 45:349–357, 2013. © 2013 Wiley Periodicals, Inc. 相似文献To describe the demographics, clinical features, and treatment outcomes with systemic steroids in eyes presenting with post-fever retinitis (PFR) from Central India.
MethodsSingle-center, retrospective analysis of 147 eyes of 98 PFR cases between 2011 and 2019.
ResultsMean age of the study cohort was 33.46?±?12.76 years, with 72 males and 26 females. The mean interval between the onset of fever and the diminution of vision was 21.10?±?13.54 days (range 0–60 days). The number of PFR cases increased over the nine years with 89 cases (90.1%) presenting during winters. Unilateral involvement was seen in 49 cases, while 49 had bilateral involvement. Clinical characteristics included: multifocal retinitis (n?=?122; 61.2%), hemorrhages (n?=?132; 89.8%), disc edema (n?=?57; 38.8%), anterior chamber reaction (n?=?28; 19%), and vitritis (n?=?103; 70.1%). Treatment included intravenous followed by oral steroids in 70 patients and oral steroids exclusively in 23; five patients denied treatment. The visual acuity improved from 1.09?±?0.52 LogMAR to 0.29?±?0.42 LogMAR (p?<?0.05).
ConclusionThere has been an increase in the prevalence of PFR cases over the last decade with clustering during the winters. Multifocal retinitis, retinal hemorrhages, and vitritis were the most common clinical findings in our series. The retinitis resolved with improvement in vision following steroid therapy in all eyes.
相似文献