基于ARIMA模型核应急卫生技术人员调配预测分析

目的 分析1995-2013年四川省医疗卫生系统卫生技术人员数并预测2014-2020年卫生技术人员需求量,从而为四川省核应急医疗卫生人力资源的有效合理调配提供参考依据。方法 从四川省卫生统计年鉴、四川卫生年鉴、四川省统计局统计公报中选取1995-2013年四川省医疗卫生系统卫生技术人员数,并运用ARIMA(1,2,1)模型对其进行分析及预测。结果 2014-2020年四川省医疗卫生技术人员数呈平稳的上升趋势,到2020年卫生技术人员需求量增至64.97万人。结论 ARIMA模型适用于卫生技术人员需求量的预测,未来四川省应加大对医疗卫生系统卫生技术人员的培养及引进力度,以保证核应急卫生人力资源的有效合理调配并提高核事故医学应急处置能力。     

甲型肝炎减毒活疫苗免疫程序的探讨

５２名ＨＡＶ抗体阴性的儿童,按０、３个月免疫程序,经２针低剂量（５．５０ｌｇＣＣＩＤ５０／ｍｌ）甲型肝炎减毒活疫苗免疫,于第２针接种后７天检测ＨＡＶ抗体阳转率为１００％,抗体效价ＧＭＴ值为１∶１４;全部接种儿童的ＡＬＴ均在正常范围内（２～２４μｌ）;免前ＨＡＶ抗体阳性的儿童,经２针免疫后,抗体效价增长在２倍以上     

高压氧治疗不同介入时机和疗程对脑外伤认知功能障碍的影响

目的 探讨高压氧治疗不同介入时机和疗程对脑外伤认知功能障碍患者认知功能的影响.方法 将90例脑外伤认知功能障碍患者按伤后高压氧治疗介入时机不同分为A组、B组和C组,每组30例;分别于伤后7～14d,15～28 d,＞28 d开始高压氧治疗,每天治疗1次,12次为1个疗程,各组在高压氧治疗前和治疗1,2,3个疗程后采用美国RLA认知功能水平分级标准评定表,评定各组患者的认知功能.结果 三组治疗1个疗程后与治疗前RLA分级比较差异无统计学意义（P＞0.05）;三组治疗2,3个疗程后与治疗1个疗程后RLA分级比较差异有统计学意义（P＜0.05）,三组治疗3个疗程后与治疗2个疗程后RLA分级比较差异有统计学意义（P＜0.05）.三组治疗1个疗程后总有效率比较差异无统计学意义（P＞0.05）.A组和B组治疗2,3个疗程后总有效率明显高于C组[73.33％（22/30）和66.67％（20/30）比46.67％（14/30）,93.33％（28/30）和86.67％（26/30）比60.00％（18/30）],差异有统计学意义（P＜0.05）,A组高于B组,但差异无统计学意义（P＞0.05）.结论 高压氧综合治疗能更有效地改善脑外伤认知功能障碍患者的认知功能,在伤后越早开始高压氧治疗效果越好,并且疗程越长疗效越佳.     

2480 WIZARD2珈玛计数器测量正电子核素^68Ga的应用研究

目的建立2480 WIZARD2珈玛计数器测定68Ga放射性活度的方法。方法制备68Ga贮备液（3.7×107Bq/mL）。倍比稀释后,用PE公司2480 WIZARD2珈玛计数器测定活度,建立标准曲线,对测量时间、精密度、重复性、稳定性及测量效率等进行研究。结果 2480 WIZARD2珈玛计数器的测量时间优选为5 s。68Ga活度在18.5~3.7×104Bq范围内线性关系良好,回归方程为：y（cpm）=24.67x（Bq）,r=0.9999。最低检测限为3.7 Bq,计数器本底值为（142±49）cpm。精密度、重复性与稳定性试验的RSD分别为0.86%,0.70%和0.71%。珈玛计数器的测量效率为（41.04±0.95）%。结论该法操作简单、快速、准确且灵敏,适用于68Ga的放射性活度测定。     

串并联机器人控制HIFU的插补算法的研究

针对高强度聚焦超声串并联机器人的硬件结构特点，插补算法采取了粗插补和精插补相结合的两级模式。为满足电机轴动态性能限制条件，同时采用了插补前加减速和插补后加减速的方法，并给出了插补算法的具体实现步骤。     

Acoustic Metamaterials for Low-Frequency Noise Reduction Based on Parallel Connection of Multiple Spiral Chambers

Acoustic metamaterials based on Helmholtz resonance have perfect sound absorption characteristics with the subwavelength size, but the absorption bandwidth is narrow, which limits the practical applications for noise control with broadband. On the basis of the Fabry–Perot resonance principle, a novel sound absorber of the acoustic metamaterial by parallel connection of the multiple spiral chambers (abbreviated as MSC-AM) is proposed and investigated in this research. Through the theoretical modeling, finite element simulation, sample preparation and experimental validation, the effectiveness and practicability of the MSC-AM are verified. Actual sound absorption coefficients of the MSC-AM in the frequency range of 360–680 Hz (with the bandwidth Δf₁ = 320 Hz) are larger than 0.8, which exhibit the extraordinarily low-frequency sound absorption performance. Moreover, actual sound absorption coefficients are above 0.5 in the 350–1600 Hz range (with a bandwidth Δf₂ = 1250 Hz), which achieve broadband sound absorption in the low–middle frequency range. According to various actual demands, the structural parameters can be adjusted flexibly to realize the customization of sound absorption bandwidth, which provides a novel way to design and improve acoustic metamaterials to reduce the noise with various frequency bands and has promising prospects of application in low-frequency sound absorption.     

大学前不同阶段同伴欺凌经历与大学生生活质量的关联研究

目的 探讨大学前不同阶段同伴欺凌经历对大学生生活质量的影响。方法 2018年10月采用分层整群抽样方法选取安徽省合肥市4所高校4 034名在校大学生作为研究对象,调查研究对象大学前不同阶段同伴欺凌经历和当前的生活质量。采用t检验和方差分析比较不同组各维度得分差异,采用多元线性回归模型分别分析大学前不同阶段欺凌经历、不同欺凌种数与大学生生活质量的关系。结果 4 034名大学生生活质量4个维度（生理、心理、社会关系和环境）得分分别为12.61±2.02、14.09±2.62、13.72±2.71和13.77±2.46。多元线性回归分析（控制相关混杂因素）结果显示,大学生在小学（β=-0.21）、中学（β=-0.27）和两阶段（β=-0.56）被言语欺凌、中学阶段被关系欺凌（β=-0.21）、中学阶段被躯体欺凌（β=-0.38）和两阶段躯体欺凌（β=-0.67）均与大学生生活质量生理维度得分呈负相关;大学生在两阶段被言语欺凌（β=-0.41）和中学阶段被关系欺凌（β=-0.42）与大学生生活质量心理维度得分呈负相关;大学生在中学阶段被关系欺凌（β=-0.32）、中学（β=-0.51）和两阶段被躯体欺凌（β=-0.57）均与大学生生活质量社会关系维度得分呈负相关;大学生在小学和两阶段被言语欺凌（β=-0.20、-0.46）和关系欺凌（β=-0.35、-0.90）均与大学生生活质量环境维度得分呈负相关,差异均有统计学意义（P<0.05）。欺凌受害指数与大学生生活质量生理、心理、社会关系和环境4个维度得分呈负相关（β=-0.33、-0.36、-0.30、-0.33）;实施欺凌指数与大学生生活质量4个维度得分也呈负相关（β=-0.28、-0.31、-0.23、-0.28）,相关性差异均有统计学意义（P<0.001）。结论 大学前不同阶段欺凌经历均与大学生生活质量各维度得分降低有关联,应加强大学前不同阶段同伴欺凌的预防控制。     

Validation of Chinese Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in patients scheduled for total knee replacement

Objective Our aim was to cross-culturally validate Chinese Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in patients with knee osteoarthritis (OA) scheduled for total knee replacement in Singapore. Methods Chinese WOMAC was translated from the original English version following standard guidelines. Patients were asked to complete a questionnaire containing the WOMAC (twice within 6 days), the Short Form 36 (SF-36), and the EuroQoL EQ-5D. Reliability was assessed using Cronbach’s alpha and intraclass correlation coefficients (ICC), dimensionality using item-to-domain correlations and factor analyses. Convergent and discriminant construct validity was assessed using six each a priori hypotheses. Results Chinese WOMAC was well accepted by the patients in the pilot test. The Chinese and English versions were therefore administered to a consecutive sample of 131 Chinese- and 127 English-speaking subjects, respectively, with knee OA. Cronbach’s alpha exceeded 0.7 for all domains except for Chinese pain domain, whereas the ICC exceeded 0.7 for all domains. Hypothesized item-to-domain correlations were observed for all items except for four items in Chinese physical function domain. The factor analyses yielded seven and five factors with eigenvalues of more than 1.0 in the Chinese and English versions, respectively. A total of 10/12 a priori construct validity hypotheses were satisfied for the Chinese version. Weak correlations between WOMAC pain and SF-36 bodily pain and moderate correlation between WOMAC pain and EQ-5D anxiety/depression were observed. Conclusions Chinese WOMAC was well accepted and demonstrated acceptable psychometric properties in Singaporean patients with severe knee OA.     

睡眠剥夺对精神-运动操作功能的影响

目的：探讨５６ｈ睡眠剥夺对精神－运动操作功能的影响。了解长时间连续睡眠剥夺中的认知功能下降程度,为制定预防措施提供科学依据。方法：选择２０名健康男性青年,采用韦氏成人智力检测的数字符号和成人神经心理检验的手指叩击测验、手指辩认和指尖认字进行测验。结果：对照组无睡眠剥夺下,经过学习迁移作用。实验２４ｈ和实验５６ｈ对数字符号后反速度以及５６ｈ右手手指叩击速度均明显加快（Ｐ〈０．０１）;实验组因睡眠剥夺