全文获取类型
收费全文 | 3754篇 |
免费 | 188篇 |
国内免费 | 26篇 |
专业分类
耳鼻咽喉 | 140篇 |
儿科学 | 242篇 |
妇产科学 | 96篇 |
基础医学 | 260篇 |
口腔科学 | 120篇 |
临床医学 | 303篇 |
内科学 | 893篇 |
皮肤病学 | 59篇 |
神经病学 | 188篇 |
特种医学 | 159篇 |
外科学 | 872篇 |
综合类 | 34篇 |
一般理论 | 2篇 |
预防医学 | 77篇 |
眼科学 | 167篇 |
药学 | 197篇 |
中国医学 | 10篇 |
肿瘤学 | 149篇 |
出版年
2024年 | 3篇 |
2023年 | 51篇 |
2022年 | 53篇 |
2021年 | 112篇 |
2020年 | 82篇 |
2019年 | 84篇 |
2018年 | 98篇 |
2017年 | 89篇 |
2016年 | 159篇 |
2015年 | 209篇 |
2014年 | 217篇 |
2013年 | 273篇 |
2012年 | 384篇 |
2011年 | 331篇 |
2010年 | 181篇 |
2009年 | 138篇 |
2008年 | 251篇 |
2007年 | 298篇 |
2006年 | 220篇 |
2005年 | 198篇 |
2004年 | 179篇 |
2003年 | 132篇 |
2002年 | 136篇 |
2001年 | 23篇 |
2000年 | 9篇 |
1999年 | 11篇 |
1998年 | 14篇 |
1997年 | 5篇 |
1996年 | 5篇 |
1995年 | 6篇 |
1994年 | 3篇 |
1993年 | 2篇 |
1992年 | 2篇 |
1990年 | 1篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1983年 | 2篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1974年 | 1篇 |
排序方式: 共有3968条查询结果,搜索用时 15 毫秒
71.
Fatih Ceran Salih Onur Basat Karaca Basaran Funda Akoz Saydam 《Journal of hand and microsurgery》2015,7(1):228-229
Trigger finger (TF) is a condition that affects quality of life and one of the most common causes of hand pain and disability. TF is characterized by catching, snapping or locking of the involved finger flexor tendon, associated with pain. TF in the children occurs rarely than in adults and partial tendon laceration is an uncommon cause of TF in the children. Thus, our aim in this study to define TF due to partial flexor tendon laceration in a child.
Electronic supplementary material
The online version of this article (doi:10.1007/s12593-015-0180-8) contains supplementary material, which is available to authorized users. 相似文献72.
Muslum Kul Fatih Unal Hasan Kandemir Bahram Sarkarati Kamer Kilinc Sultan Basmac? Kandemir 《Psychiatry investigation》2015,12(3):361-366
Objective
Oxidative metabolism is impaired in several medical conditions including psychiatric disorders, and this imbalance may be involved in the etiology of these diseases. The present study evaluated oxidative balance in pediatric and adolescent patients with attention deficit hyperactivity disorder (ADHD).Methods
The study included 48 children and adolescents (34 male, 14 female) with ADHD who had no neurological, systemic, or comorbid psychiatric disorders, with the exception of oppositional defiant disorder (ODD), and 24 sex- and age-matched healthy controls (17 male and seven female).Results
TAS was significantly lower, and TOS and OSI were significantly higher in patients with ADHD than in healthy controls. Total antioxidant levels were lower in patients with comorbid ODD than in those with no comorbidity. No difference was found in TOS or OSI among the ADHD subtypes; however, TAS was higher in the attention-deficient subtype.Conclusion
Our findings demonstrated that oxidative balance is impaired and oxidative stress is increased in children and adolescents with ADHD. This results are consistent with those of previous studies. 相似文献73.
74.
Abdullah Ekizer Mehmet Emir Yalvac Tancan Uysal Mehmet Fatih Sonmez Fikrettin Sahin 《The Angle orthodontist》2015,85(3):394
Objective:To transplant bone marrow–derived mesenchymal stem cells (MSCs) into the interpremaxillary suture after rapid maxillary expansion with the aim of increasing new bone formation in the suture.Materials and Methods:Nineteen male Wistar rats were divided into two groups (control, n = 9; experimental, n = 10). Both groups were subjected to expansion for 5 days, and 50 cN of force was applied to the maxillary incisors with a helical spring. Pkh67+ (green fluorescent dye)–labeled MSCs were applied to the interpremaxillary suture after force application into the interpremaxillary suture of rats. Bone formation in the sutural area was histomorphometrically evaluated, including the amount of new bone formation (µm2), number of osteoblasts, number of osteoclasts, and number of vessels. Mann-Whitney U-test was used for statistical evaluation at the P < .05 level.Results:After 10 days of retention, Pkh67+ can be detected in suture mostly in the injection site under fluorescence microscope. Histomorphometric analysis revealed that a single local injection of MSCs into the midpalatal suture increased the new bone formation in the suture by increasing the number of osteoblasts and new vessel formation, compared with controls injected with phosphate-buffered saline.Conclusions:This preclinical study might provide foundations for the underlying potential clinical use of MSCs after maxillary expansion. Given the fact that MSCs are currently in use in clinical trials, this approach might be a feasible treatment strategy to accelerate new bone tissue formation in midpalatal suture and to shorten the treatment period for patients undergoing maxillary expansion reinforcement 相似文献
75.
76.
Muhsin Kaya Fatih Aydin Hüseyin Büyükbayram 《The Turkish journal of gastroenterology》2005,16(4):236-239
A 41-year-old man presenting with lower abdominal pain, constipation, abdominal distention, fever (37.5 degrees C) and fatigue was evaluated, and a mass localized to the left lower abdomen was identified. Radiographic and colonoscopic examination revealed a stricture 10 cm in length localized to the sigmoid-descending colon junction. The diagnosis of amebiasis was confirmed by histological examination of a biopsy specimen taken from the stricture and stool examination. One month after the initiation of metronidazole treatment, complete clinical and laboratory improvement was observed. In the differential diagnosis of colonic stricture, amebiasis should also be considered. 相似文献
77.
Ömer Nuri Pamuk Umut Kalyoncu Kenan Aksu Ahmet Omma Yavuz Pehlivan Yonca Çağatay Orhan Küçükşahin Salim Dönmez Gözde Yıldırım Çetin Rıdvan Mercan Özün Bayındır Ayşe Çefle Fatih Yıldız Ayşe Balkarlı Levent Kılıç Necati Çakır Bünyamin Kısacık Mustafa Ferhat Öksüz Veli Çobankara Ahmet Mesut Onat Mehmet Sayarlıoğlu Mehmet Akif Öztürk Gülsüm Emel Pamuk Nurullah Akkoç 《Rheumatology international》2016,36(7):945-953
In this multicenter, retrospective study, we evaluated the efficacy and safety of biologic therapies, including anti-TNFs, in secondary (AA) amyloidosis patients with ankylosing spondylitis (AS) and rheumatoid arthritis (RA). In addition, the frequency of secondary amyloidosis in RA and AS patients in a single center was estimated. Fifty-one AS (39M, 12F, mean age: 46.7) and 30 RA patients (11M, 19F, mean age: 51.7) with AA amyloidosis from 16 different centers in Turkey were included. Clinical and demographical features of patients were obtained from medical charts. A composite response index (CRI) to biologic therapy—based on creatinine level, proteinuria and disease activity—was used to evaluate the efficacy of treatment. The mean annual incidence of AA amyloidosis in RA and AS patients was 0.23 and 0.42/1000 patients/year, respectively. The point prevalence in RA and AS groups was 4.59 and 7.58/1000, respectively. In RA group with AA amyloidosis, effective response was obtained in 52.2 % of patients according to CRI. RA patients with RF positivity and more initial disease activity tended to have higher response rates to therapy (p values, 0.069 and 0.056). After biologic therapy (median 17 months), two RA patients died and two developed tuberculosis. In AS group, 45.7 % of patients fulfilled the criteria of good response according to CRI. AS patients with higher CRP levels at the time of AA diagnosis and at the beginning of anti-TNF therapy had higher response rates (p values, 0.011 and 0.017). During follow-up after anti-TNF therapy (median 38 months), one patient died and tuberculosis developed in two patients. Biologic therapy seems to be effective in at least half of RA and AS patients with AA amyloidosis. Tuberculosis was the most important safety concern. 相似文献
78.
79.
Exome sequencing identifies a homozygous C5orf42 variant in a Turkish kindred with oral‐facial‐digital syndrome type VI
下载免费PDF全文
![点击此处可从《American journal of medical genetics. Part A》网站下载免费的PDF全文](/ch/ext_images/free.gif)
80.
Eftal Murat Bakirci Levent Demirtas Husnu Degirmenci Selim Topcu Selami Demirelli Hikmet Hamur Mutlu Buyuklu Emin Murat Akbas Adalet Ozcicek Fatih Ozcicek Gokhan Ceyhun Ergun Topal 《Clinics (S?o Paulo, Brazil)》2015,70(2):73-80