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101.
NO,iNOS与胃癌关系的研究进展 总被引:10,自引:7,他引:3
幽门螺杆菌(H.pylori)感染造成的炎症反应,可刺激诱导型NO合酶(inducible NO synthase,iNOS)产生大量的NO,对胃癌的启动和发展起重要作用.进入20世纪90年代以来,一氧化氮(NO)研究跨入了迅猛发展的阶段,许多调节功能及其在病理生理过程中所起的重要作用被逐渐认识,特别是NO在致癌和致突变过程中表现的双重性,更是近年的研究热点之一[1,2].本文就NO、iNOS与胃癌关系的研究进展作一综述. 相似文献
102.
A comparison of the fully repositionable and retrievable Boston Lotus and direct flow medical valves for the treatment of severe aortic stenosis: A single center experience
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Francesco Giannini MD Azeem Latib MD Matteo Montorfano MD Neil Ruparelia MD Vittorio Romano RT Matteo Longoni RT Luca Ferri MD Richard Jabbour MD Antonio Mangieri MD Damiano Regazzoli MD Marco Ancona MD Nicola Buzzatti MD Lorenzo Azzalini MD Akihito Tanaka MD Eustachio Agricola MD Alaide Chieffo MD Ottavio Alfieri MD Antonio Colombo MD 《Catheterization and cardiovascular interventions》2018,91(5):966-974
103.
Comparison of sitting and supine forced vital capacity in collagen VI‐related dystrophy and laminin α2‐related dystrophy
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![点击此处可从《Pediatric pulmonology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Katherine G. Meilleur PhD Melody M. Linton BS Joseph Fontana MD Anne Rutkowski MD Jeffrey Elliott MA Mark Barton RT Peter McGraw RT Angela Kokkinis BSN Sandra Donkervoort MS Meganne Leach MSN Minal Jain DSc Jahannaz Dastgir DO James Collins MD Rhonda Szczesniak PhD Kelly Yang PhD Hemant Sawnani MD Carsten G. Bönnemann MD 《Pediatric pulmonology》2017,52(4):524-532
104.
M. TROSSAËRT P. BOISSEAU A. QUEMENER M. SIGAUD M. FOUASSIER C. TERNISIEN A. LEFRANÇOIS‐BETTEMBOURG C. TESSON C. THOMAS S. BEZIEAU 《Journal of thrombosis and haemostasis》2011,9(3):524-530
Summary. Background: In most laboratories, the severity of hemophilia A is assessed by the factor VIII activity (FVIII:C) one‐stage assay. However, comparisons of these results with those of two‐stage assays can reveal discrepancies and suggest misdiagnosis. Patients/Methods: In this monocentric study, we measured FVIII:C with two methods (one‐stage chronometric and chromogenic assays) in 307 (173 families) patients with moderate/mild hemophilia A. To compare results, we used a chronometric/chromogenic ratio. Discrepancy was defined as a ratio < 0.5 or > 1.5. We studied their putative involvement at known FVIII functional sites, their interspecies conservation status, and their spatial position within the FVIII structure. Results: Thirty‐six patients from 17 families exhibited a discrepancy between the two assays: 12 (6.9%) families had a low ratio (< 0.5), and five (2.9%) families had a high ratio (> 1.5). Qualitative deficiency was diagnosed in about 16% of the families. Molecular studies were performed in 15 of these 17 families, resulting in each case in the identification of missense mutations, including three novel mutations. We were further able to propose a pathophysiologic explanation. Conclusions: In this monocentric study, we have demonstrated a discrepancy between FVIII:C assay results in 10% of families with moderate/mild hemophilia A. The prevalence of ‘inverse’ discrepancy (i.e. low chronometric/chromogenic ratio) is high as compared with previous reports. We suggest that both FVIII:C assays are recommended in patients with moderate/mild hemophilia A for a complete biological phenotype. This could also improve our knowledge of the FVIII structure–function relationships. 相似文献
105.
Samir B. Pancholy MD FACC FSCAI Joseph Sweeney RT 《Catheterization and cardiovascular interventions》2011,78(5):809-812
Upper extremity venous access provides a safer alternative for performance of right heart catheterization compared to femoral venous access. We describe a technique to access deep veins of the upper extremity, in patients undergoing transradial catheterization, using levophase contrast venography. This technique allows the operator to access deep veins of the upper extremity without the need for additional equipment, staff or training, using traditional basic catheterization laboratory skills and equipment. © 2011 Wiley‐Liss, Inc. 相似文献
106.
B. Scott Cook MD Cleve Wilson RT Brooke Kaiser RT Raj Baljepally MD 《Catheterization and cardiovascular interventions》2017,90(6):945-947
A 45‐year old male with no prior cardiac history, presented with cardiogenic shock in the setting of an anterolateral ST elevation myocardial infarction. We first placed a 2.5 Impella for hemodynamic support, and proceeded with emergent percutaneous coronary intervention to the proximal LAD. Several hours following percutaneous coronary intervention (PCI), the patient became acutely hypotensive and an echocardiogram revealed the Impella catheter was kinked within the left ventricle. The patient was taken back to the cath lab for Impella adjustment; however, damage to the distal catheter required the Impella be exchanged. As the patient was therapeutically anticoagulated and on dual antiplatelet therapy, we modified the Impella catheter in order to maintain existing vascular access during Impella exchange. This case demonstrates our method for maintaining vascular access during Impella exchange, thereby eliminating the need for a second arterial puncture. © 2017 Wiley Periodicals, Inc. 相似文献
107.
Expanded clinical use of everolimus eluting bioresorbable vascular scaffolds for treatment of coronary artery disease
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Roberto Diletti MD PhD Yuki Ishibashi MD PhD Cordula Felix MD Yoshinobu Onuma MD Shimpei Nakatani MD Nicolas M. van Mieghem MD PhD Eveliyn Regar MD PhD Marco Valgimigli MD PhD Peter P. de Jaegere MD PhD Nienke van Ditzhuijzen MD Jiang Ming Fam MBBS MD Jurgen M.R. Ligthart RT Mattie J. Lenzen PhD Patrick W. Serruys MD PhD Felix Zijlstra MD PhD Robert Jan van Geuns MD PhD 《Catheterization and cardiovascular interventions》2017,90(1):58-69
108.
Masanori Ozaki MS Yusuke Inoue MD PhD Tosiaki Miyati PhD DMSc Hirohumi Hata RT Sinya Mizukami RT Shotaro Komi RT Keiji Matsunaga MD Reiko Woodhams MD PhD 《Journal of magnetic resonance imaging : JMRI》2013,37(1):172-178
Purpose:
To assess the effect of motion artifact reduction on the diffusion‐weighted magnetic resonance imaging (DWI‐MRI) of the liver, we compared velocity‐compensated DWI (VC‐DWI) and VC‐DWI combined with tetrahedral gradients (t‐VC‐DWI) to conventional DWI (c‐DWI) in the assessment of apparent diffusion coefficients (ADCs) of the liver.Materials and Methods:
In 12 healthy volunteers, the liver was scanned with c‐DWI, VC‐DWI, and t‐VC‐DWI sequences. The signal‐to‐noise ratio (SNR) and ADC of the liver parenchyma were measured and compared among sequences.Results:
The image quality was visually better for t‐VC‐DWI than for the others. The SNR for t‐VC‐DWI was significantly higher than that for VC‐DWI (P < 0.05) and comparable to that for c‐DWI. ADCs in both hepatic lobes were significantly lower for t‐VC‐DWI than for c‐DWI (P < 0.01). ADC in the left lobe was significantly lower for VC‐DWI than for c‐DWI (P < 0.01). Although ADC in the left lobe was significantly higher for c‐DWI (P < 0.01), no significant differences in ADCs were found between the right and left lobes for VC‐DWI and t‐VC‐DWI.Conclusion:
The use of a t‐VC‐DWI sequence enables us to correct ADCs of the liver for artificial elevation due to cardiac motion, with preserved SNR. J. Magn. Reson. Imaging 2013;37:172–178. © 2012 Wiley Periodicals, Inc. 相似文献109.
Expert Panel on MR Safety: Emanuel Kanal MD A. James Barkovich MD Charlotte Bell MD James P. Borgstede MD William G. Bradley Jr MD PhD Jerry W. Froelich MD J. Rod Gimbel MD John W. Gosbee MD Ellisa Kuhni‐Kaminski RT Paul A. Larson MD James W. Lester Jr MD John Nyenhuis PhD Daniel Joe Schaefer PhD Elizabeth A. Sebek RN BSN Jeffrey Weinreb MD Bruce L. Wilkoff MD Terry O. Woods PhD Leonard Lucey JD Dina Hernandez BSRT 《Journal of magnetic resonance imaging : JMRI》2013,37(3):501-530
Because there are many potential risks in the MR environment and reports of adverse incidents involving patients, equipment and personnel, the need for a guidance document on MR safe practices emerged. Initially published in 2002, the ACR MR Safe Practices Guidelines established de facto industry standards for safe and responsible practices in clinical and research MR environments. As the MR industry changes the document is reviewed, modified and updated. The most recent version will reflect these changes. J. Magn. Reson. Imaging 2013;37:501–530. © 2013 Wiley Periodicals, Inc. 相似文献
110.
Rami Doukky MD MSc FACC Nathan Frogge MBA Yohannes A. Bayissa MD Gautam Balakrishnan MD Jacob M. Skelton CNMT RT Kara Confer BS Kalindi Parikh MD Russell F. Kelly MD FACC 《Journal of nuclear cardiology》2013,20(5):774-784