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31.
Background: This observational study was conducted in a small, 45 bed border static hospital, located in a field area, where no blood bank facilities were available. The present study was conducted to elucidate the blood transfusion practices of this hospital. 相似文献
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34.
Turliuc D Dumitrescu GF Indrei A 《Revista medico-chirurgical?? a Societ????ii de Medici ??i Naturali??ti din Ia??i》2007,111(3):649-657
The aim of the neurosurgical treatment in neuro-oncology is multiple: diagnostic (obtaining of a precise histopathological diagnosis to improve the treatment and the further prognosis), symptomatic (the improvement of the neurological clinical features by decreasing intracranial pressure) and therapeutic (to obtain a cytoreductive treatment, by complete or partial exeresis of the tumoural mass). To establish a precise histopathological diagnosis, during the intervention and latter, on the paraffin sections, the neuropathologist must examine the neurosurgical drawings knowing the history of the illness, the clinical and radiological aspects of the case in study, which complains a good cooperation between neurosurgeon and neuropathologist. To initiate the procedures of histopathological processing of various neurosurgical drawings, the neuropathologist must understand very well the surgical procedure. This is the reason of this study: to present different neurosurgical technics; the choose of one of these essentially depends on the location and size of the cerebral tumour, on neuroradiological characteristics and presumptive histopathological diagnosis and on the neurological status, the age and the general condition of the patient. 相似文献
35.
Hiroaki Haruguchi Kotaro Suemitsu Naoko Isogai Masaaki Murakami Masahiko Fujihara Kazuhiro Iwadoh Jeremiah Menk Hiroko Ookubo Tomonari Ogawa the IN.PACT AV Access Investigators 《Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy》2023,27(4):682-693
Purpose
There is a lack of adjudicated and prospectively randomized published outcomes on the use of drug-coated balloons (DCB) to treat dysfunctional arteriovenous fistula in Asian patients. This post hoc subgroup analysis of 112 Japanese participants from the global IN.PACT AV Access trial reports outcomes through 12 months.Materials and Methods
Participants were treated with DCB (n = 58) or standard non-coated percutaneous transluminal angioplasty (PTA) balloons (n = 54). Outcomes included target lesion primary patency (TLPP), access circuit primary patency, and safety.Results
Through 6 months, TLPP was 86.0% (49/57) in the DCB group and 49.1% (26/53) in the PTA group (p < 0.001). Through 12 months, TLPP was 67.3% (37/55) in the DCB group and 43.4% (23/53) in the PTA group (p = 0.013).Conclusion
In this post hoc analysis of Japanese participants from the IN.PACT AV Access trial, participants treated with DCB had higher TLPP through 6 and 12 months compared with PTA. 相似文献36.
37.
Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice 总被引:8,自引:0,他引:8
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Pohlenz J Dumitrescu A Zundel D Martiné U Schönberger W Koo E Weiss RE Cohen RN Kimura S Refetoff S 《The Journal of clinical investigation》2002,109(4):469-473
Three genes, TTF1, TTF2, and PAX8, involved in thyroid gland development and migration have been identified. Yet systematic screening for defects in these genes in thyroid dysgenesis gave essentially negative results. In particular, no TTF1 gene defects were found in 76 individuals with thyroid dysgenesis even though a deletion of this gene in the mouse results in thyroid and lung agenesis and defective diencephalon. We report a 6-year-old boy with predominant dyskinesia, neonatal respiratory distress, and mild hyperthyrotropinemia. One allele of his TTF1 gene had a guanidine inserted into codon 86 producing a nonsense protein of 407, rather than 371, amino acids. The mutant TTF1 did not bind to its canonical cis-element or transactivate a reporter gene driven by the thyroglobulin promoter, a natural target of TTF1. Failure of the mutant TTF1 to interfere with binding and transactivation functions of the wild-type TTF1 suggested that the syndrome was caused by haploinsufficiency. This was confirmed in mice heterozygous for Ttf1 gene deletion, heretofore considered to be normal. Compared with wild-type littermates, Ttf1(+/-) mice had poor coordination and a significant elevation of serum thyrotropin. Therefore, haploinsufficiency of the TTF1 gene results in a predominantly neurological phenotype and secondary hyperthyrotropinemia. 相似文献
38.
This case report discusses the unusual presentation and ultrasound features of a solitary fibrous tumour of the face. Solitary fibrous tumour is an uncommon form of soft tissue tumour which, although seen predominantly within the lung pleura, can occur throughout the body in sites such as the peritoneum, mediastinum and head and neck. Ultrasound is an excellent imaging modality in the assessment of soft tissue masses in the head and neck. The ultrasound features demonstrated by this example of solitary fibrous tumour are reviewed. This report also highlights that ultrasound alone is ultimately limited in reaching a definitive diagnosis. The roles of other investigations such as ultrasound-guided biopsy and cross-sectional imaging are discussed. 相似文献
39.
Beta thalassemia in Melanesia: association with malaria and characterization of a common variant (IVS-1 nt 5 G----C) 总被引:3,自引:0,他引:3
Data on the distribution of beta thalassemia among over 6,000 Melanesians reveals a major difference in the carrier rates between populations in the malarious coastal regions of New Guinea and those living in the historically malaria-free Highlands. The island of Maewo in Vanuatu has a particularly high incidence of beta + thalassemia associated with a single restriction enzyme haplotype. Direct cloning into a plasmid vector and sequence analysis demonstrate that the mutation is a G to C transversion at position 5 of intron 1 of the beta- globin gene. Oligonucleotide probe surveys indicate that this variant accounted for all cases of beta thalassemia studied from Maewo. It is also common in coastal Papua New Guinea where haplotype and oligonucleotide probe data suggest that the molecular basis of beta thalassmia is more heterogeneous. 相似文献
40.
AC Chambers AV Patil R Alves JC Hopkins J Armstrong RN Lawrence 《Annals of the Royal College of Surgeons of England》2012,94(8):548-551