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101.
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目的:研究中国汉族群体中α艾杜糖苷酶基因D4S111位点的遗传多态性。方法:采用扩增片段长度多态性(AmpFLP)分析技术,检测了广州地区汉族无血缘关系健康个体97名。结果:D4S111位点,在97名无关个体中发现5个等位基因和9种基因型,等位基因片段长度为830~510bp,基因频率为00052~03608,PIC为05966,杂合性为078。结论:中国汉族群体中D4S111位点具有高度多态性,并与其它种族间存在差异性。 相似文献
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OBJECTIVE: To detect the amino acid neurotransmitters in cerebrospinal fluid of patients in persistent vegetative state (PVS) to define their relation to the clinical manifestations of the patients. METHODS: The cerebrospinal fluid from 46 patients in PVS and 20 control patients were collected for detection of glutamic acid, aspartic acid, alanine and glycine by high-performance liquid chromatography. RESULTS: All the four amino acids were separated by chromatography within 25 min. The contents of all the 4 neurotransmitters in PVS group were higher than those in the control group, and their contents were inversely correlated to PVS score of the patients. The differences in the concentration of glycine and alanine were significant between PVS patients and the control patients (P<0.05). CONCLUSION: The patient's clinical manifestations are related to the contents of amino acid neurotransmitters in the cerebrospinal fluid of PVS patients. 相似文献
106.
额叶内侧面损伤的临床特点及救治 总被引:9,自引:0,他引:9
目的 总结17例额叶内侧面损伤的临床特点及救治经验。方法 对我科1999年7月至2003年4月收治的额叶内侧面损伤患者进行回顾性分析。结果 手术治疗1例,恢复良好,保守治疗16例,其中恢复良好12例,中残2例,死亡2例,全组死亡率11.77%。结论 额叶内侧面损伤一般意识障碍较轻,但易直接发生枕骨大孔疝,严密观察病情及动态CT检查,颅内压监测,不拘泥传统手术指征,及时抓住手术时机,可有效降低致残率及死亡率。 相似文献
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张宇 文天夫 陈哲宇 严律南 梁冠林 李国 张显华 冉顺 廖志学 ZHANG Yu WEN Tian-fu CHEN Zhe-yu YAN Lü-nan LIANG Guan-lin LI Guo ZHANG Xian-hua RAN Shun LIAO Zhi-xue 《中华普通外科杂志》2004,24(1):470-472
Objective To observe changes of hepatic hemodynamics and hepatic functional reserve after splenectomy and periesophagogastric devascularization. Methods From July 2006 to August 2007, thirty patients with portal hypertension caused by hepatitis B cirrhosis underwent splenectomy and periesophagogastric devascuiarization. The PVPG (portal venous pressure gradient) was measured by inductor continually during operation. The HAF (hepatic artery flow), PVF (portal venours flow) and hepatic arterial RI(resistant index) were measured with Doppler sonography. The EHBF(effective hepatic blood flow) and ICGR15 (indocyaninegreen retention rate at 15 minutes) were obtained respectively by indocyaninegreen clearance test before and after the operation. Results PVPG after laparotomy (19±4) mm Hg, ligating the splenic artery(14±4) mm Hg, splenectomy(14±3)mm Hg and periesophagogastric devascularization (12±4) mm Hg showed a tendency to decrease progressively. The PVF decreased [from (42±14) ml/s to (16±8) ml/s] and HAF increased in compensation after operation. The EHBF increased [from (0.48±0.10) L/min to (0.56±0.10) L/min], and the ICGR15 decreased (from 23%±8% to 18%±4%) postoperatively. Conclusion After splenectomy and periesophagogastric devascularization, the hepatic functional reserve improves at least in a short term notwithstanding the decrease of PVPG and PVF. 相似文献
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Pan Jing-xin Guo Yi-bin Guo Xi-zhe Guo Jian-xin Chen Yun-feng Wang Zhi-dong 《中国结合医学杂志》2004,10(1):36-39
Objective: To explore the effect of Shenfu Injection, SFI) on the secondary aplastic anemia (AA) of tumor patients after chemotherapy
(CT).Methods: The 15 cases of SFI treated group, 10 cases of control group, 25 cases of SFI + granulocyte-macrophage colony stimulating
factor (GMCSF) treated group and the group of 23 GM-CSF-treated tumor cases of secondary AA after CT were compared, with their
increasing rate and the rebound speed of neutrophil, platelet, bone marrow nucleated RBC, granulocyte, and megakaryocyte all
being investigated.Results: The increasing rate and rebound speed of granulocyte, platelet, and the increasing rate of bone marrow nucleated RBC, granulocyte,
megakaryocyte were obviously higher than those of the control, and the clinical manifestations were also obviously improved.
The increasing rate of platelet, bone marrow nucleated RBC, megakaryocyte of the SFI + GM-CSF group were higher than those
of the group which used GM-CSF alone, while the increasing rate of granulocyte in blood and bone marrow in both groups was
similar.Conclusion: Significant efficacy was shown in SFI for the treatment of secondary AA of tumor patients after CT. 相似文献