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101.
102.
Christopher J. Collins Fan Yi Remwilyn Dayuha Phi Duong Simon Horslen Michelle Camarata Ayse K. Coskun Roderick H.J. Houwen Tudor L. Pop Heinz Zoller Han-wook Yoo Sung Won Jung Karl H. Weiss Michael L. Schilsky Peter Ferenci Si Houn Hahn 《Gastroenterology》2021,160(7):2367-2382.e1
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103.
Kadir Desdicioglu Mehmet Ali Malas Selen Bahceci Fatma Simsek Ayse Gizem Polat 《Journal of the Anatomical Society of India》2017,66(1):37-42
Introduction
In our study, the aim was to anatomically and histologically investigate the morphometric structures of the branches involved in the sural nerve and sural nerve formation.Method
The study was conducted on 46 lower extremities of 23 fetuses which were obtained from Izmir Katip Çelebi University, Atatürk Training and Research Hospital, with ages from 18 and 32 gestational weeks, without any external pathology or anomaly. During the study period, the posterior-side skin dissection of the lower extremity was performed with the aid of a surgical dissection microscope initially, and the structures forming the sural nerve and the sural nerve were exposed and made visible. Afterwards, sections were taken from these structures for morphometric measurements and histological examination.Results
The mean values and standard deviations of morphometric measurements obtained were determined. Separately, it was determined that there was no statistical difference between right-left sides and genders in morphometric measurements (p > 0.05). The sural nerve was determined to be differentiated into 4 types as A, B, C and D according to the way the nerve branches forming sural nerve join. In addition, differing characteristics pertaining to the sural nerve and branches were determined.Discussion
We are of the opinion that the data obtained in our study will be of use to neurologists, orthopedists and clinicians engaged in this region during interventional procedures. 相似文献104.
105.
106.
Ayse Tosun Gul Serdaroglu Muzaffer Polat Hasan Tekgul Sarenur Gokben 《Indian journal of pediatrics》2009,76(5):547-550
Objective We aimed to describe the epidemiologic, clinical, laboratory features, neuroimaging, treatment, and outcome of children with
acute disseminated encephalomyelitis in a cohort study.
Methods In this study, twelve children who were diagnosed as acute disseminated encephalomyelitis were reviewed retrospectively. All
of the cases were reevaluated with systemic and neurological examinations, serologic tests, cerebrospinal fluid investigations,
magnetic resonance imaging.
Result Their age ranged between 2.5 and 16 years. Five of the cases had initial infections. Patients presented most often with motor
deficits (75%), secondly with loss of conscious (33%), and seizures (33%). Spinal fluid abnormalities occurred in 41.6%. Cranial,
and spinal magnetic resonance imaging (MRI) revealed hyperintense signal changes mainly in basal ganglia and thalamus (58%),
cortical and subcortical areas (33) in T2 weighted images. Myelitis was determined in two cases. Six patients were treated
with steroid, and 3 were treated with intravenous immunoglobulin. Ten patients recovered completely. We observed relapse in
one case and recurrence in two cases. These cases responded well to high dose intravenous prednisolone followed by oral prednisolone
for 6 months.
Conclusion Outlook recovery is generally good in acute disseminated encephalomyelitis. Recurrence and neurological deficits are rarely
seen. Early treatment of prednisolone is one of the most important factors to determine the prognosis in this disease. 相似文献
107.
Fatih Kose Ayberk Besen Saime Paydas Mustafa Balal Gulfiliz Gonlusen Tamer Inal Ayse Dogan Mustafa Kibar 《Clinical and experimental nephrology》2010,14(1):22-27
Background
Nonsteroidal anti-inflammatory drugs act by inhibiting the rate-limiting enzymes cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2), which are important in prostanoid formation. The aim of this experimental study was to examine the effects of selective Cox-2 inhibitor, rofecoxib, with or without furosemide, on urine and serum electrolytes, creatinine clearance, plasma renin activity (PRA), and Cox-2 expression in the renal cortex. 相似文献108.
109.
Ayse Oytun Bayrak MD Ilkay Koray Bayrak MD Hande Turker MD Muzaffer Elmali MD Mehmet Selim Nural MD 《Muscle & nerve》2010,41(5):661-666
The aim of this study was to determine the diagnostic value of ultrasonographic measurements in ulnar neuropathy at the elbow (UNE) and to assess the relationship between the measurements and the electrophysiological severity. The largest anteroposterior diameter (LAPD) and cross‐sectional area (CSA) measurements of the ulnar nerve were noted at multiple levels along the arm, and the distal‐to‐proximal ratios were calculated. Almost all of the measurements and swelling ratios between patients and controls showed statistically significant differences. The largest CSA, distal/largest CSA ratio, CSA at the epicondyle, and proximal LAPD had larger areas under the curve than other measurements. The sensitivity and specificity in diagnosing UNE were 95% and 71% for the largest CSA, 83% and 85% for the distal/largest CSA ratio, 83% and 81% for the CSA at the epicondyle, and 93% and 43% for the proximal LAPD, respectively. There was a statistically significant correlation between the electrophysiological severity scale score (ESSS) and the largest CSA, the CSA at the epicondyle and 2 cm proximal to the epicondyle, and the LAPD at the level of the epicondyle (P < 0.05). None of the swelling ratios showed a significant correlation with the ESSS. The largest CSA measurement is the most valuable ultrasonographic measurement both for diagnosis and determining the severity of UNE. Muscle Nerve, 2010 相似文献
110.
Aims: Nitric oxide (NO) attenuates many functions within the kidney, and all NO synthase (NOS) isoforms are constitutively expressed in the kidney. But the exact role of NO in renal diseases is still debatable. The aim of the present study was to investigate endothelial ( eNOS ), and neuronal ( nNOS ) NOS gene polymorphisms in children with minimal change nephrotic syndrome (MCNS).
Materials and methods: Eighty-six Turkish children with clinical MCNS, ranging in age from 2 to 10 years, were compared with 114 healthy age- and sex-matched controls. The glu 298 Asp (G/T) polymorphism of the eNOS, and C276T (C/T) polymorphism of nNOS genes were genotyped using polymerase chain reaction.
Results: The distribution of GG, TG, and TT genotypes for eNOS was 52%, 33% and 15% in MCNS compared with 61%, 26% and 13% in the controls ( P > 0.05). The distribution of CC, TC, and TT genotypes for nNOS was 16%, 66% and 18% in MCNS compared with 10%, 43% and 47% in the controls. TT genotype distribution of nNOS was found to be lower in patients ( P = 0.003). The eNOS and nNOS gene polymorphisms were not associated with gender, positive family history, frequency of relapses, or response to steroid.
Conclusions: The present study is the first to investigate eNOS and nNOS gene polymorphisms in children with MCNS. The nNOS gene polymorphism may be associated with MCNS in children, but further studies in a larger population with different glomerular diseases are needed to confirm the results. 相似文献
Materials and methods: Eighty-six Turkish children with clinical MCNS, ranging in age from 2 to 10 years, were compared with 114 healthy age- and sex-matched controls. The glu 298 Asp (G/T) polymorphism of the eNOS, and C276T (C/T) polymorphism of nNOS genes were genotyped using polymerase chain reaction.
Results: The distribution of GG, TG, and TT genotypes for eNOS was 52%, 33% and 15% in MCNS compared with 61%, 26% and 13% in the controls ( P > 0.05). The distribution of CC, TC, and TT genotypes for nNOS was 16%, 66% and 18% in MCNS compared with 10%, 43% and 47% in the controls. TT genotype distribution of nNOS was found to be lower in patients ( P = 0.003). The eNOS and nNOS gene polymorphisms were not associated with gender, positive family history, frequency of relapses, or response to steroid.
Conclusions: The present study is the first to investigate eNOS and nNOS gene polymorphisms in children with MCNS. The nNOS gene polymorphism may be associated with MCNS in children, but further studies in a larger population with different glomerular diseases are needed to confirm the results. 相似文献