胸部高分辨率CT检查技术的临床应用

笔者对５０例肺部疾病胸部常规ＣＴ和高分辨率ＣＴ（ＨＲＣＴ）图像进行了对照分析。其中特发性肺间质纤维化（ＩＦＰ）８例，肺转移癌５例，支气管扩张１５例，慢性阻塞性肺气肿１５例，周围型肺癌７例，结果表明：ＨＲＣＴ在ＩＦＰ、支气管扩张和肺气肿的显示明显优于常规ＣＴ（Ｐ＜０．００１），在对肺部原发或转移性肿瘤的显示能提供更多的诊断信息。笔者还讨论了ＨＲＣＴ的检查技术和图像后处理，分析了影响ＨＲＣＴ的若干因素，指出通过缩小视野（ＦＯＶ），减少象素做图像的重建放大显示肺部局部结构更为清楚方便，应灵活运用。     

A preliminary study of the changes in the direct-acting mutagenicities of several nitropolycyclic aromatic hydrocarbons after exposure under sunlight

Five commercially available nitropolyclyclic aromatic hydrocarbons (nitro-PAH), namely, 4-nitrobiphenyl, 2-nitrofluorene, 9-nitroanthracene, 1-nitropyrene, and 2,7-dinitrofluorene, were exposed under restricted sunlight in the open air. The direct-acting mutagenicities of the samples after an exposure of 45 days were measured in order to compare them with those of the original samples in the Ames Salmonella typhimurium bioassay. It was found that the mutagenicities of some nitro-PAH do not change significantly while the mutagenicities of others increase or decrease after exposure. A preliminary study of nitro-PAH reaction products after exposure using GC, GC/MS, and FT-IR is also reported.     

庆大霉素经乳汁的排泄

采用荧光偏振免疫法测定１４例剖宫产术后应用肌注或静点庆大霉素的产妇乳汁及血清中庆大霉素的浓度，结果表明肌注或静点庆大霉素后３￣５小时，乳汁中浓度达峰值，血清中庆大霉素的浓度于给药后０．５小时达峰值。提示：无论肌注或静脉给庆大霉素均可经乳汁排泄，乳母不宜应用庆大霉素，即使产后已应用庆大霉素，应停药１３小时后方可哺乳。     

高质量电镜影象幻灯片的简便制作方法

使用135单镜头反光照相机和近摄接圈,加置一个普通印相晒箱,即可对电镜底片直接成像,精确的曝光,配合标准程序冲洗,一步制成135幻灯片。其质量优良,且简便可靠、省工省时、节约材料,能大大提高工作效率。本文较为详细地介绍了具体操作方法及要点,并对其它常用制作方法亦做了分析讨论。     

小儿先天性髋关节脱位近年来应用术式的演变及其评估

本文介绍本院近４年来小儿先天性髋脱位治疗应用术式的演变。由２０多年来一直喜欢用骨盆截骨术演变为近１年来用得最多的是造盖术。近４年共手术４６３例，５６５髋。实践证明：比起骨盆截骨术，造盖术显得更简便，侵袭小，不需二次手术拔除内固定针。因在我国大龄髋脱位偏多，造盖术更适合我国国情。经过一些改进，可以克服造盖折断和吸收问题。     

膀胱移行细胞癌分级诊断的研究中三种定量分析方法的评价

应用ＨＩ－ＣＩ真彩色病理图像分析仪对８６例移行细胞癌的核形态，ＤＮＡ量和ＡｇＮｏＲｓ颗粒进行了定量分析。三种方法分别和综合作分级判别分析。分级结果与ＷＨＯ分级结果对比并分析他们与预后的关系。结果证明，三种定量方法在膀胱癌分级诊断中都是比较客观而有价值的方法。１级癌的判别效果最好，一致率为９０．９％～１００％。各种方法分级与ＷＨＯ一致率以形态定量法较好，为８６．０％，ＡｇＮｏＲｓ为７７．９％，ＤＮＡ为７６．７％。对预后估计的价值以ＡｇＮｏＲｓ法最好，ＤＮＡ法次之。三种方法综合分级判别可稍提高分级诊断一致率，达８８．４％。     

An etiological study on fulminant viral hepatitis]

Viral markers were studied in 79 cases of viral hepatitis with hepatic failure. The results were shown as follows: 8 cases were positive for anti-HAV IgM (10.12%); 76 cases positive for HBsAg or anti-HBc IgM (96.20%) and 41 cases positive for anti-HCV antibodies (51.89%). Among those with anti-HCV positive, 35 cases were co-infected with HBV, 5 cases with HAV and/or HCV, only one was infected with HCV alone 2 cases were HD-Ag positive (2.52%) and one not identified (1.27%). With the reference of clinical findings, patients co-infected with HBV/HCV or anti-HBc IgM positive were more critical and usually entail higher mortality. In cases with HCV co-infections, the positive HBV replication markers seems to be reduced. Hepatic failure without HBV replicative markers had a high rate of hepatic coma as well as poor outcome.     

我国八个人群血压,血脂,血糖,纤维蛋白原的相互关系分析

对国内饮食习惯迥异、住四个地区、属四个民族的八个人群,共724名男性(年龄40～59岁),作血糖、血胆固醇(TC)、三酸甘油酯(TG)、血浆纤维蛋白原、血压(BP)间的相关分析。发现:1.血脂在摄入大量动物性食物(羊肉为主)的新疆三民族组最高;2.血脂在摄入羊肉最多、维生素 C 最少的哈萨克族反低于居同一地区的汉、维吾尔族;3.TC、TG、血糖相互间呈正相关.TC 与 BP 间不但在总合并组、且在正常血压组也正相关,提示在高血压的一级预防中也应包括高 TC 的预防;原发性高血压可能存在与醣、脂肪代谢障碍相关的“镶嵌”模式.     

视网膜脱离手术复位后ERG的恢复

为探讨视网膜脱离手术复位后ERG的改变，对35例（35眼）患者进行手术前后ERG检测，结果表明；（1）视网膜脱离术前ERGa、b波幅明显低于有视网膜格子样变性而无脱离者。（2）手术复位后ERGa、b波幅随时间延长逐渐回升。（3）视网膜脱离范围二个象限以内者ERGa、b波幅回升高于二象限以上者。（4）手术范围一个象限以内者与超过一个象限者相比前者ERG恢复优于后者。（5）视网膜脱离时间2月以内与超过2月相比，ERG恢复前者明显优于后者。结果证实视网膜脱离术后ERG恢复与手术后时间、脱离范围、病程及手术范围密切相关。