外伤性牙槽损伤固定方法的临床研究

目的　分析方丝弓托槽技术和牙弓夹板技术在外伤性牙槽损伤的临床应用。　方法　随机将 91例外伤性牙槽损伤需进行单颌固定的患者分为两组 ,共 134颗牙齿 ,分别采用方丝弓托槽技术和常规牙弓夹板技术固定 ,记录患者复诊过程中固定装置的稳固情况 ,以及半年后临床疗效和牙周相关指标 ,并进行统计学处理。　结果　两组患者复诊过程中固定装置稳固情况和在牙龈炎、牙周袋形成、牙槽骨吸收的改变上差异有非常显著性意义 (P <0 .0 1) ,在临床疗效评定结果上差异无显著性意义 (P >0 .0 5 )。　结论　方丝弓托槽技术是治疗外伤性牙槽损伤可靠的单颌固定方法     

蛋白芯片检测系统(多肿瘤标志物C12系统)的应用评价

目的：应用并评价蛋白芯片检测系统(多肿瘤标志物C12)的临床价值。方法：应用雅培电化学发光系统(ECL)和C12系统双盲法检测41份血清标本。结果：在对照检测达10份标本的AFP、CEA、β-HCG三个项目，C12系统和ECL系统符合性达81．8％以上；C12系统多个指标间可相互支持其准确性，并有助于判断肿瘤来源。结论：C12系统具有较高准确性，其指标间可相互支持，并有助于判断肿瘤源性。     

正常妊娠和妊娠高血压综合征孕妇血清脂质的过氧化作用

目的　探讨脂质过氧化作用在正常妊娠时的生理和妊娠高血压综合征 (妊高征 )时的致病机制。方法　应用美国CIBA 5 6 0全自动生化分析仪及 72 2分光光度计对正常孕妇 178例、妊高征孕妇 2 4 6例、正常晚期孕妇 178例和正常未孕妇女 6 2例 (对照组 )的血清中SOD ,LPO ,NO及总抗氧化能力进行测定比较。结果　正常妊娠晚期的SOD活性及LPO水平高于非妊娠妇女 (P <0 .0 5 ) ,妊高征患者中脂质过氧化物水平显著高于同期正常妊娠水平 (P <0 .0 5 ) ,而且随病情严重程度而升高。妊高征患者NO水平低于正常妊娠妇女 (P <0 .0 5 )。NO水平随妊高征病情进展而逐渐降低。结论　SOD ,LPO ,NO的合成、释放在妊高征的病理变化中起重要作用     

Simple measurement of spinal cord evoked potential: a valuable data source in the rat spinal cord injury model.

Measurement of spinal cord evoked potentials (SCEPs) is proposed as a means of predicting locomotion outcome in the rat spinal cord injury (SCI) model. Using 55 rats, three reproducible peak waves (waves I, II and III) were observed during stimulation at the C7 level with recording at the L1 epidural space. Hemisection at the T13 level showed three wave loss patterns: wave III loss only, loss of both wave II and III, and loss of all three waves. Defining an ideal SCI model as establishment of stable monoparesis or paraparesis, all animals in the wave II-III loss group showed favorable results. Histological data and electrophysiological properties allowed reasonable assumptions of wave origin: wave I from extrapyramidal tracts, wave II from the ventral corticospinal tract, and wave III from the dorsal corticospinal tract. Complete destruction of pyramidal tracts in both dorsal and ventral fibers was essential for long-term impairment of locomotion.     

The effect of pre-vertebroplasty tumor ablation using laser-induced thermotherapy on biomechanical stability and cement fill in the metastatic spine

A biomechanical study comparing simulated lytic vertebral metastases treated with laser-induced thermotherapy (LITT) and vertebroplasty versus vertebroplasty alone. To investigate the effect of tumor ablation using LITT prior to vertebroplasty on biomechanical stability and cement fill patterns in a standardized model of spinal metastatic disease. Vertebroplasty in the metastatic spine is aimed at reducing pain, but is associated with risk of cement extravasation in up to 10%. Six pairs of fresh-frozen cadaveric thoracolumbar spinal motion segments were tested in axial compression intact, with simulated metastases and following percutaneous vertebroplasty with or without LITT. Canal narrowing under load, pattern of cement fill, load to failure, and LITT temperature and pressure generation were collected. In all LITT specimens, cement filled the defect without extravasation. The canal extravasation rate was 33% in specimens treated without LITT. LITT and vertebroplasty yielded a trend toward improved posterior wall stability (P = 0.095) as compared to vertebroplasty alone. Moderate rises in temperature and minimal pressure generation was seen during LITT. In this model, elimination of tumor by LITT, facilitates cement fill, enhances biomechanical stability and reduces the risk of cement extravasation.     

Bilateral versus unilateral sudden sensorineural hearing loss.

OBJECTIVES: To analyze the clinical characteristics and treatment results between bilateral (bi-) and unilateral (uni-) sudden sensorineural hearing loss (SSNHL). STUDY DESIGN AND SETTING: A retrospective study. METHODS: Three hundred twenty-four patients with SSNHL were classified into two groups; simultaneous bi-SSNHL (n = 16) and uni-SSNHL (n = 308). We compared clinical characteristics, medical history, hearing level, and treatment results between the 2 groups. RESULTS: The incidence of bi-SSNHL was 4.9 percent of overall patients with SSNHL. Bi-SSNHL occurs more commonly in patients of older age, with preexisting diabetes mellitus, and lipid panel abnormalities compared with uni-SSNHL. Ten patients (62.5%) in the bi-SSNHL group showed hearing recovery in 1 or both ears compared with 56.5 percent of patients with uni-SSNHL. Only 12 (37.5%) of all 32 ears recovered in bi-SSNHL, which was significantly lower than in uni-SSNHL. CONCLUSION: Bi-SSNHL has a very low incidence and lower recovery rate than uni-SSNHL. Recognition of similarities and differences between bilateral and unilateral SSNHL can help in counseling and managing the patients.