全文获取类型
收费全文 | 34628篇 |
免费 | 3489篇 |
国内免费 | 2526篇 |
专业分类
耳鼻咽喉 | 212篇 |
儿科学 | 490篇 |
妇产科学 | 391篇 |
基础医学 | 4231篇 |
口腔科学 | 623篇 |
临床医学 | 4469篇 |
内科学 | 5411篇 |
皮肤病学 | 314篇 |
神经病学 | 1556篇 |
特种医学 | 1146篇 |
外国民族医学 | 29篇 |
外科学 | 3754篇 |
综合类 | 5988篇 |
现状与发展 | 9篇 |
一般理论 | 3篇 |
预防医学 | 2398篇 |
眼科学 | 935篇 |
药学 | 3750篇 |
32篇 | |
中国医学 | 2002篇 |
肿瘤学 | 2900篇 |
出版年
2024年 | 166篇 |
2023年 | 696篇 |
2022年 | 1661篇 |
2021年 | 2105篇 |
2020年 | 1456篇 |
2019年 | 1246篇 |
2018年 | 1223篇 |
2017年 | 1142篇 |
2016年 | 1049篇 |
2015年 | 1557篇 |
2014年 | 1952篇 |
2013年 | 1759篇 |
2012年 | 2494篇 |
2011年 | 2800篇 |
2010年 | 1724篇 |
2009年 | 1363篇 |
2008年 | 1724篇 |
2007年 | 1819篇 |
2006年 | 1688篇 |
2005年 | 1612篇 |
2004年 | 1148篇 |
2003年 | 1104篇 |
2002年 | 962篇 |
2001年 | 784篇 |
2000年 | 761篇 |
1999年 | 767篇 |
1998年 | 457篇 |
1997年 | 467篇 |
1996年 | 363篇 |
1995年 | 343篇 |
1994年 | 328篇 |
1993年 | 187篇 |
1992年 | 228篇 |
1991年 | 228篇 |
1990年 | 237篇 |
1989年 | 188篇 |
1988年 | 152篇 |
1987年 | 123篇 |
1986年 | 123篇 |
1985年 | 96篇 |
1984年 | 71篇 |
1983年 | 44篇 |
1982年 | 28篇 |
1981年 | 23篇 |
1980年 | 16篇 |
1979年 | 20篇 |
1977年 | 16篇 |
1975年 | 14篇 |
1974年 | 19篇 |
1969年 | 13篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
141.
142.
碱性成纤维细胞生长因子和胰岛素样生长因子—Ⅰ及其协同作用对?… 总被引:5,自引:2,他引:3
目的 研究碱性成纤维细胞生长因子(basic fibroblast growth factor,bFGF)、胰岛素样生长因子-1(insulin-like growth factor-1,IGF-1)及二者的共同作用对体外牛晶体上皮细胞(bovine lensepithelial cell,BLEC)增殖的影响。方法 BLEC原代培养,取第4例细胞种入24孔板,加入不同浓度的bFGF、IGF-1, 相似文献
143.
A spot weld & heating treatment tri-uses device based on modern mechanical-electric technique, was developed for dental spot weld, stainless steel orthodontic wire heating-reversion and Ni-Ti orthodontic wire heating-overload metamorphism. The device will be very helpful instrument in orthodontic clinic. The paper not only described the operating methods of the device, but also discussed the Performance-improved principles of stainless steel orthodontic wire and the principles of heating overload metamorphism of Ni-Ti orthodontic wire. 相似文献
144.
左旋四氢巴马汀对单个豚鼠心室肌细胞钙电流的阻滞作用 总被引:4,自引:0,他引:4
AIM: To study the effect of l-tetrahydropalmatine (l-THP) on L-type calcium channel. METHODS: Patch clamp technique (whole cell recording) was used to record L-Ca2+ current in single cardiac myocyte. RESULTS: 1) l-THP 1, 10, and 100 micromol.L-1 reduced ICa-max from (999 +/- 93) pA to (700 +/- 111) pA, (582 +/- 66) pA, and (420 +/- 112) pA (n = 6, P < 0.01), respectively. 2) l-THP reduced the voltage at half-maximal inactivation (V1/2) of L-Ca2+ channel to more negative potentials by 9 mV (n = 5, P < 0.05). 3) l-THP caused both tonic and use-dependent reduction of Ca2+ current. Tonic block of l-THP on Ca2+ current was 46% +/- 8% (n = 6, P < 0.01). The degree of use dependent blocking was 13.5% +/- 2.4% (n = 6, P < 0.05) at 1 Hz, the degree increased to 44% +/- 5% (n = 6, P < 0.01) at 3 Hz. 4) l-THP delayed half-recovery time of Ca2+ channel recovery from inactivity from (94 +/- 39) ms to (170 +/- 42) ms(n = 6, P < 0.01). CONCLUSION: l-THP has a moderate inhibitory effect on L-Ca2+ current. 相似文献
145.
目的:探讨妊高征患者胎儿脐动脉血流速度比值(S/D)与围产儿预后的关系,方法:应用彩色超声波对98例妊高征患者胎儿脐动脉血流速度指数进行测量并与新生儿体重,新生儿Apgar评分,羊水性质和围产期结局的关系进行分析,结果:98例妊高征中有34例围产儿预后良好,64例围产儿预后不良,围产儿预后不良发生率,中,重度妊高征明显高于轻度妊高征(P〈0.01),S/D比值与围产儿预后的程度业的相关性,结论,产 相似文献
146.
Nakashima R Enomoto T Fujita M Yoshino K Wada H Kondo K Yao M Murata Y 《Oncology reports》1996,3(5):887-890
The von Hippel-Lindau (VHL) tumor suppressor gene has been shown to be mutated frequently not only in neoplasms from von Hippel-Lindau disease, but also in sporadic clear cell renal carcinoma. In order to reveal the possible role of the VHL tumor suppressor gene in the development of ovarian carcinoma, a total of 71 primary sporadic ovarian carcinomas were analyzed for the presence of mutations in the exon 2 and 3 of the VHL tumor suppressor gene, using the polymerase chain reaction with single strand conformation polymorphism analysis. No mutations in the VHL gene were found in any of the tumors analyzed. This result shows that the VHL tumor suppressor gene does not play a major role in the tumorigenesis of sporadic ovarian carcinoma. 相似文献
147.
The ideal methodology for quality of life (QOL) measurement in cancer clinical trials matches the evaluation to the anticipated outcomes, thereby increasing the likelihood that clinically relevant changes are captured. The present study explored the importance of such methodological tailoring in a phase II trial of paclitaxel and recombinant human granulocyte-colony stimulating factor (rhG-CSF) for metastatic breast cancer. Prior to the trial, clinical observation suggested that frequent short-lived episodes of pain might occur during this treatment regimen. Twenty-one patients provided longitudinal data for at least three cycles of chemotherapy. To assess transient pain, aroutine QOL assessment at baseline and every third cycle was supplemented with pain measurements twice weekly. The interval assessment included a multidimensional QOL instrument (Functional Living Index-Cancer) and measures of psychological state (Rand Mental Health Inventory), symptom distress (Memorial Symptom Assessment Scale), and performance status (Karnofsky Performance Status Score). The frequent pain measurements were acquired using visual analogue and categorical scales for pain intensity (Memorial Pain Assessment Card). From baseline to the end of cycle three, global pain scores declined and the results on other QOL measures were variable. The data obtained using these measures did not reveal the existence of episodic pains. In contrast, the twice weekly pain measurements clearly demonstrated transient severe pains in approximately half the patients. These data highlight the importance of specific measurement of troubling symptoms or other relevant QOL concerns at clinically appropriate intervals during the routine QOL assessment of clinical trials. The additional burden involved in these assessments is warranted if the information derived is highly relevant, would not be adequately captured otherwise and could improve therapy. 相似文献
148.
149.
150.
目的:观察气至病所针法的临床治疗效果。方法:将120例臀上皮神经损伤病例随机分成“气至病所”针法组与常规针法组进行对照观察。结果:气至病所组治愈率优于常规组(P<0.01)。结论:“气至病所”针法是一种治疗臀上皮神经损伤的有效方法。 相似文献