Four outstanding young Chinese scientists received the 2013 Scholar Award from the US Chinese Anti-Cancer Association and the National Foundation for Cancer Research

To facilitate and strengthen collaborations among cancer researchers and physicians in the United States and China, the US Chinese Anti- Cancer Association （USCACA） and the National Foundation for Cancer Research （NFCR） have established the Scholar Excellence Award for the USCACA-NFCR Scholar Exchange and Fellowship Program in Basic, Translational, and Clinical Studies. Since 2010, 10 young Chinese researchers and physicians have received the award for their outstanding achievements in cancer research accomplished while in the United States, as well as their continuing efforts in eradicating cancer after their return to China. This year, USCACA and NFCR selected 4 young scientists for their excellence in basic or clinical cancer research. Here, we are proud to introduce these 4 winners of the 2013 USCACA-NFCR Scholar Excellence Award：     

不同哺乳动物红细胞溶血替代眼刺激实验的比较

背景：哺乳动物红细胞溶血实验单独或组合使用可替代体内Draize兔眼实验,用于化合物眼刺激性的标识、筛查或机制研究。但目前尚不清楚不同物种间的红细胞差异是否会对实验结果造成影响。目的：比较大鼠和五指山小型猪血红细胞用于溶血实验的物质分类结果。方法：分别制备两种动物的红细胞悬液,进行红细胞溶血实验。分析溶血和蛋白变性两个毒性终点,得到50%溶血浓度HD50、蛋白变性指数DI及H/D比值3个参数值。结果与结论：经22种已知分类的眼刺激物检测表明,两种动物血样对化合物的分类差别无显著性意义（P〉0.05）。Wilcoxon符号秩和检验小型猪血与大鼠血对物质分类差异无显著性意义（S=8,P=0.3047）,经Kappa一致性检验,得出小型猪血和大鼠血的一致性一般[Kappa=0.4211,置信区间为（0.1433,0.6988）]。即种属差异对物质分类结果影响不大。