全文获取类型
收费全文 | 74256篇 |
免费 | 7124篇 |
国内免费 | 4020篇 |
专业分类
耳鼻咽喉 | 762篇 |
儿科学 | 1140篇 |
妇产科学 | 784篇 |
基础医学 | 6605篇 |
口腔科学 | 1275篇 |
临床医学 | 8321篇 |
内科学 | 8971篇 |
皮肤病学 | 1261篇 |
神经病学 | 2855篇 |
特种医学 | 2680篇 |
外国民族医学 | 13篇 |
外科学 | 7811篇 |
综合类 | 16027篇 |
现状与发展 | 21篇 |
一般理论 | 19篇 |
预防医学 | 7086篇 |
眼科学 | 1770篇 |
药学 | 7943篇 |
95篇 | |
中国医学 | 6104篇 |
肿瘤学 | 3857篇 |
出版年
2024年 | 264篇 |
2023年 | 1048篇 |
2022年 | 2441篇 |
2021年 | 3209篇 |
2020年 | 2671篇 |
2019年 | 1805篇 |
2018年 | 2005篇 |
2017年 | 2195篇 |
2016年 | 1906篇 |
2015年 | 2957篇 |
2014年 | 3706篇 |
2013年 | 4248篇 |
2012年 | 6284篇 |
2011年 | 6531篇 |
2010年 | 5101篇 |
2009年 | 4518篇 |
2008年 | 5073篇 |
2007年 | 5050篇 |
2006年 | 4504篇 |
2005年 | 3871篇 |
2004年 | 2789篇 |
2003年 | 2238篇 |
2002年 | 1874篇 |
2001年 | 1652篇 |
2000年 | 1489篇 |
1999年 | 1008篇 |
1998年 | 478篇 |
1997年 | 407篇 |
1996年 | 319篇 |
1995年 | 326篇 |
1994年 | 275篇 |
1993年 | 191篇 |
1992年 | 323篇 |
1991年 | 308篇 |
1990年 | 286篇 |
1989年 | 259篇 |
1988年 | 228篇 |
1987年 | 214篇 |
1986年 | 204篇 |
1985年 | 160篇 |
1984年 | 111篇 |
1983年 | 71篇 |
1982年 | 57篇 |
1981年 | 53篇 |
1979年 | 73篇 |
1978年 | 51篇 |
1977年 | 52篇 |
1974年 | 65篇 |
1973年 | 60篇 |
1972年 | 63篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
51.
52.
严晓璐 《中国医疗器械信息》2006,12(11):27-28
2006年10月31日,由国药励展展览有限责任公司,中国医疗器械行业协会主办的2006中国医疗器械产业政策研讨会在郑州国际会展中心隆重召开,中国医疗器械行业协会姜峰会长为大会致开幕词。 相似文献
53.
目的:探讨下颈椎的屈曲程度与后路经寰枢关节螺钉固定术的可能性。方法:回顾已施行经寰枢关节螺钉固定术病例的术前颈椎过屈位X线像,测量C2~C7间的角度,复习手术经过,分析可完成螺钉固定的颈椎曲度及其它相关因素。结果:在已完成后路经寰枢关节螺钉固定术的75例患者中有58例屈颈侧位X线像显示下颈椎呈后凸状态,后凸角平均为17.25°;另17例屈颈侧位片见下颈椎呈前凸状态,但这些病例都是体形瘦长者。结论:后路经寰枢关节螺钉固定术仅适合于下颈椎可以很好屈曲及体形瘦长的病例。 相似文献
54.
55.
Ya Zumeng Gao Zhi Zhang Gang Wang Jianhua Tan Yinghui 《Otolaryngology--head and neck surgery》2006,135(3):458-462
OBJECTIVE: To reduce the incidence of sensory deficits and Frey's syndrome by modifying the traditional superficial parotidectomy. STUDY DESIGN: After raising the skin flap, the parotid gland fascia (PGF) was elevated to form a posterior pedicle fascial flap and then was replaced after the gland removal. The great auricular nerve (GAN) that runs within the PGF was not separated, so both the GAN and the PGF were preserved. Before this modification, the GAN and PGF were examined anatomically. The complication rates in the modified and control groups were compared. RESULTS: 1) The GAN, which runs within the thick and pycnotic PGF, trifurcates into postauricular, preauricular and lobule branches. The modification could be carried out practically based on the anatomy study. 2) Long-term sensory deficit was encountered in 13.3% of the control group, but 0% in the modified one. Frey's syndrome was suffered by 66.7% and 16.7% cases in the control and modified group respectively. The incidence of other complications was not significantly different. CONCLUSION: Our modification is practical. It decreases the complications significantly. EBM rating: B-3b. 相似文献
56.
低位直肠癌保留神经的腹膜外侧方扩大清扫的效果分析 总被引:1,自引:1,他引:0
目的 探讨低位直肠癌保留神经的腹膜外侧方扩大清扫对患者术后生存率、排尿功能和性功能的影响。方法 回顾性分析我院1996年1月至2000年6月期间收治的392例进展期低位直肠癌实施保留神经的根治性切除术患者的临床资料,其中行腹腔内清扫173例,腹腔内加腹膜外侧方清扫219例,2组患者在年龄、性别、浸润肠壁深度及肿瘤病理组织学类型方面差异无统计学意义。结果 腹腔内加腹膜外侧方清扫组侧方淋巴结转移率为17.8%(39/219),侧方盆壁非连续性癌灶转移率为5,9%(13/219)。术后发生排尿功能障碍:腹腔内清扫组7例(4.0%),腹腔内加腹膜外侧方清扫组113例(51.6%),2组比较差异有统计学意义(P〈0.01);性功能障碍:腹腔内清扫组93例男性患者中有12例(12.9%),腹腔内加腹膜外侧方清扫组119例男性患者中有62例(52.1%),2组比较差异有统计学意义(P〈0.01);局部复发率:腹腔内清扫组为16.2%(28/173),腹腔内加腹膜外侧方清扫组为9.6%(21/219),2组比较差异有统计学意义(P〈0.05);5年生存率:腹腔内清扫组为49.1%(85/173),腹腔内加腹膜外侧方清扫组为59.4%(130/219),2组比较差异有统计学意义(P〈0.05)。结论 低位直肠癌保留神经的腹膜外侧方扩大清扫,可以减少局部复发,提高患者5年生存率,但也会影响患者术后排尿和男性性机能。 相似文献
57.
58.
PINK1 mutations in sporadic early-onset Parkinson's disease. 总被引:5,自引:0,他引:5
Eng-King Tan Kenneth Yew Eva Chua K Puvan Hui Shen Esther Lee Kim-Yoong Puong Yi Zhao Ratnagopal Pavanni Meng-Cheong Wong Dominic Jamora Deidre de Silva Kyaw-Thu Moe Fung-Peng Woon Yih Yuen Louis Tan 《Movement disorders》2006,21(6):789-793
Pathogenic PINK1 mutations have been described in PARK6-linked Parkinson's disease (PD) patients of Asian origin. However, data on the frequency of PINK1 mutations in sporadic early-onset Parkinson's disease (EOPD) Asian patients are lacking. The objectives of this study were to report the frequency of PINK1 mutations of sporadic EOPD in an Asian cohort comprising of ethnic Chinese, Malays, and Indians, and to highlight a PINK1-positive patient who presented with restless legs symptoms. Eighty consecutive sporadic EOPD patients from the movement disorder clinics of two major tertiary institutions in the country were included. We performed sequence analysis of all the coding and exon-intron junctions of the PINK1 using specific primer sets. In addition, we genotyped polymorphisms detected from the analysis in a group of sporadic PD patients and controls. Three different mutations (two homozygous nonsense and one heterozygous missense) in the putative kinase domain were found in three patients, giving a 3.7% frequency of PINK1 mutations in our EOPD cohort. All the mutations were absent in 200 healthy controls. One patient with a novel homozygous nonsense PINK1 mutation presented unusually with restless legs symptoms. Separately, analysis of the frequency of four PINK1 polymorphisms in a group of sporadic PD and controls did not reveal any significant differences. We highlight a 3.7% frequency of PINK1 mutations in an Asian cohort (ethnic Chinese, Malay, and Indian) of EOPD. The phenotypic spectrum associated with PINK1-positive patients may be wider than previously reported. Polymorphisms of PINK1 do not appear to modulate risk of PD in our population. 相似文献
59.
A R Molina H Brasch S T Tan 《Journal of plastic, reconstructive & aesthetic surgery》2006,59(12):1458-1462
One serious complication of neurofibromatosis type 1 (NF1) is the development of malignant peripheral nerve sheath tumours (MPNSTs). These malignancies often develop within pre-existing plexiform neurofibromas and their development is now thought to be associated with both tumour suppressor gene mutations and dysregulated growth factor signalling. Recent work demonstrates that the lifetime risk of malignant transformation is significantly greater than previously thought. Ionising radiation, a long-standing disease, particularly the presence of a large number of plexiform neurofibromas from an early age, are suggested risk factors. We present an NF1 patient who developed an MPNST of the cervical vagus nerve which was successfully treated with surgery. Close monitoring of patients with NF and a high level of suspicion towards rapidly enlarging and painful swellings is merited as these features may signify malignant transformation. Whether a positive history of MPNST in other affected family members predisposes the individual to a higher risk of malignant transformation is unclear. 相似文献
60.
中青年脑梗死68例临床分析 总被引:1,自引:0,他引:1
脑梗死多见于老年人,但近年来中青年(16-45岁)患者逐渐增多且有年轻化趋势,深人探讨中青年脑梗死的致病因素及临床表现对其防治有重要意义。本文回顾性分析了我院自1998年1月到2004年12月问收治的中青年脑梗死患者68例,现报告如下。 相似文献