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991.
Louise F. Wilson Andrew N. Page Nathan A.M. Dunn Nirmala Pandeya Melinda M. Protani Richard J. Taylor 《Maturitas》2013
Objectives
To quantify the population attributable risk of key modifiable risk factors associated with breast cancer incidence in Queensland, Australia.Study design
Population attributable fractions (PAFs) for high body mass index (BMI), use of hormone replacement therapy (HRT), alcohol consumption and inadequate physical activity were calculated, using prevalence data from a representative survey of women attending mammographic screening at BreastScreen Queensland in 2008 and relative risk estimates sourced from published literature. Attributable cancers were calculated using ‘underlying’ breast cancer incidence data for 2008 based on Poisson regression models, adjusting for the inflation of incidence due to the effects of mammographic screening.Main outcome measures
Attributable burden of breast cancer due to high body mass index (BMI), use of hormone replacement therapy (HRT), alcohol consumption and inadequate physical activity.Results
In Queensland women aged 45–69 years, an estimated 12.1% (95% CI: 11.6–12.5%) of invasive breast cancers were attributable to high BMI in post-menopausal women who have never used HRT; 2.8% (95% CI: 2.7–2.9%) to alcohol consumption; 7.6% (95% CI: 7.4–7.9%) to inadequate physical activity in post-menopausal women and 6.2% (95% CI: 5.5–7.0%) to current use of HRT after stratification by BMI and type of HRT used. Combined, just over one quarter (26.0%; 95% CI: 25.4–26.6%) of all invasive breast cancers in Queensland women aged 45–69 years in 2008 were attributable to these modifiable risk factors.Conclusions
There is benefit in targeting prevention strategies to modify lifestyle behaviours around BMI, physical activity, HRT use and alcohol consumption, as a reduction in these risk factors could decrease invasive breast cancer incidence in the Queensland population. 相似文献992.
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994.
Alex D. Federman Michael Wolf Anastasia Sofianou Elizabeth A.H. Wilson Melissa Martynenko Ethan A. Halm Howard Leventhal Juan P. Wisnivesky 《Patient education and counseling》2013
Objective
Suboptimal health literacy (HL) and asthma beliefs are associated with poor asthma self-management and outcomes. We tested the hypothesis that low HL is associated with inaccurate beliefs.Methods
Asthmatics ≥60 were recruited from hospital and community practices in New York, NY and Chicago, IL (n = 420). HL was measured with the Short Test of Functional Health Literacy in Adults; validated instruments derived from the self regulation model were used to assess beliefs. The association of beliefs with HL was evaluated with multivariate models.Results
Thirty-six percent of patients had low HL; 54% believed they only have asthma when symptoms are present, 29% believed they will not always have asthma and 20% believed that their doctor can cure asthma. HL was associated with beliefs of not having asthma all the time and that asthma can be cured (OR: 1.84, 95% CI: 1.2–2.82; OR: 2.22, 95% CI: 1.29–3.82, respectively). Patients with low HL were also more likely to be concerned about medication use (β = 0.92, p = .05), despite recognizing their necessity (β = −1.36, p = .01).Conclusions
Older asthmatics with low HL endorse erroneous asthma beliefs.Practice implications
Health communications for improving self-management behaviors in asthma should employ both health literacy-appropriate strategies and messages to counter illness-related misconceptions. 相似文献995.
Michael G Fehlings Jetan H Badhiwala Henry Ahn H Francis Farhadi Christopher I Shaffrey Ahmad Nassr Praveen Mummaneni Paul M Arnold W Bradley Jacobs K Daniel Riew Michael Kelly Darrel S Brodke Alexander R Vaccaro Alan S Hilibrand Jason Wilson James S Harrop S Tim Yoon Kee D Kim Branko Kopjar 《Lancet neurology》2021,20(2):98-106
996.
Dionne Kringos Wienke Boerma Yann Bourgueil Thomas Cartier Toni Dedeu Toralf Hasvold Allen Hutchinson Margus Lember Marek Oleszczyk Danica Rotar Pavlic Igor Svab Paolo Tedeschi Stefan Wilm Andrew Wilson Adam Windak Jouke Van der Zee Peter Groenewegen 《The British journal of general practice》2013,63(616):e742-e750
Background
A suitable definition of primary care to capture the variety of prevailing international organisation and service-delivery models is lacking.Aim
Evaluation of strength of primary care in Europe.Design and setting
International comparative cross-sectional study performed in 2009–2010, involving 27 EU member states, plus Iceland, Norway, Switzerland, and Turkey.Method
Outcome measures covered three dimensions of primary care structure: primary care governance, economic conditions of primary care, and primary care workforce development; and four dimensions of primary care service-delivery process: accessibility, comprehensiveness, continuity, and coordination of primary care. The primary care dimensions were operationalised by a total of 77 indicators for which data were collected in 31 countries. Data sources included national and international literature, governmental publications, statistical databases, and experts’ consultations.Results
Countries with relatively strong primary care are Belgium, Denmark, Estonia, Finland, Lithuania, the Netherlands, Portugal, Slovenia, Spain, and the UK. Countries either have many primary care policies and regulations in place, combined with good financial coverage and resources, and adequate primary care workforce conditions, or have consistently only few of these primary care structures in place. There is no correlation between the access, continuity, coordination, and comprehensiveness of primary care of countries.Conclusion
Variation is shown in the strength of primary care across Europe, indicating a discrepancy in the responsibility given to primary care in national and international policy initiatives and the needed investments in primary care to solve, for example, future shortages of workforce. Countries are consistent in their primary care focus on all important structure dimensions. Countries need to improve their primary care information infrastructure to facilitate primary care performance management. 相似文献997.
Susan J Wilson Jonathan A Ward Helen M Pickett Simonetta Baldi Ana R Sousa Peter J Sterk Kian Fan Chung Ratko Djukanovic Barbro Dahlen Bo Billing Dominick Shaw Norbert Krug Thomas Sandstrӧm Christopher Brightling Peter H Howarth the U-BIOPRED consortium 《Clinical and experimental allergy》2021,51(2):296-304
998.
999.
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von Mühlen Carlos
Alberto Garcia-De La Torre Ignacio Infantino Maria Damoiseaux Jan Andrade Luis E. C. Carballo Orlando Gabriel Conrad Karsten Francescantonio Paulo Luiz Carvalho Fritzler Marvin J. Herold Manfred Klotz Werner de Melo Cruvinel Wilson Mimori Tsuneyo Satoh Minoru Musset Lucile Chan Edward K. L. 《Immunologic research》2021,69(6):594-608
Immunologic Research - Results of the anti-nuclear antibodies-indirect immunofluorescence assay (anti-cell antibodies test) on HEp-2 cell substrates should be communicated to clinicians in a... 相似文献