全文获取类型
收费全文 | 939篇 |
免费 | 24篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 17篇 |
妇产科学 | 22篇 |
基础医学 | 107篇 |
口腔科学 | 1篇 |
临床医学 | 94篇 |
内科学 | 397篇 |
皮肤病学 | 11篇 |
神经病学 | 25篇 |
特种医学 | 8篇 |
外科学 | 81篇 |
综合类 | 10篇 |
一般理论 | 1篇 |
预防医学 | 80篇 |
眼科学 | 1篇 |
药学 | 39篇 |
中国医学 | 5篇 |
肿瘤学 | 69篇 |
出版年
2022年 | 5篇 |
2021年 | 20篇 |
2020年 | 5篇 |
2019年 | 12篇 |
2018年 | 21篇 |
2017年 | 6篇 |
2016年 | 12篇 |
2015年 | 11篇 |
2014年 | 25篇 |
2013年 | 37篇 |
2012年 | 52篇 |
2011年 | 53篇 |
2010年 | 36篇 |
2009年 | 38篇 |
2008年 | 58篇 |
2007年 | 87篇 |
2006年 | 76篇 |
2005年 | 71篇 |
2004年 | 62篇 |
2003年 | 57篇 |
2002年 | 57篇 |
2001年 | 5篇 |
2000年 | 6篇 |
1999年 | 13篇 |
1998年 | 6篇 |
1997年 | 9篇 |
1996年 | 8篇 |
1995年 | 8篇 |
1993年 | 3篇 |
1991年 | 9篇 |
1990年 | 5篇 |
1989年 | 4篇 |
1988年 | 3篇 |
1987年 | 7篇 |
1986年 | 4篇 |
1984年 | 6篇 |
1983年 | 3篇 |
1982年 | 7篇 |
1981年 | 3篇 |
1980年 | 8篇 |
1978年 | 3篇 |
1977年 | 3篇 |
1976年 | 4篇 |
1975年 | 6篇 |
1974年 | 4篇 |
1971年 | 2篇 |
1969年 | 2篇 |
1966年 | 2篇 |
1965年 | 3篇 |
1961年 | 2篇 |
排序方式: 共有970条查询结果,搜索用时 156 毫秒
101.
Aronow WS 《Geriatrics》2005,60(2):24, 26-24, 28
Cardiac resynchronization therapy (CRT) significantly improves functional status, exercise duration, left ventricular (LV) ejection fraction, death from progressive congestive heart failure (CHF), and hospitalization for CHF in patients with moderate-to-severe CHF, an abnormal LV ejection fraction, and a QRS duration on the electrocardiogram of 120 msec or more. In these patients, CRT reduces all-cause mortality, though not significantly. However, CRT plus. an implantable cardioverter-defibrillator (ICD) significantly reduces all-cause mortality. Compared with placebo, ICD therapy significantly reduced all-cause mortality by 33% in patients with class II or III CHF, an abnormal LV ejection fraction, and a QRS duration on the electrocardiogram of 120 msec or more. 相似文献
102.
103.
Ravi Prakash Krishna Moorthy Wilbert S. Aronow 《Catheterization and cardiovascular interventions》1976,2(4):381-387
We evaluated the relationship of S1 recorded by phonocardiography at the mitral area with motion of the mitral, tricuspid, and aortic valves, recorded by simultaneous echocardiography in 20 cardiac patients with a normal PR interval. The first major component of S1 coincided with mitral valve closure in 20 of 20 patients (100%) and also with tricuspid valve closure in 14 of 20 patients (70%). The second major component of S1 coincided with aortic valve opening in 20 of 20 patients and also with tricuspid valve closure in six of 20 patients (30%). We conclude that the first major component of S1 coincides with mitral valve closure in all patients but may also coincide with tricuspid valve closure in many patients, and the second major component of S1 coincides with aortic valve opening in all patients but may also coincide with tricuspid valve closure in some patients. 相似文献
104.
Coronary risk factors should be modified in older persons after myocardial infarction (MI). Aspirin 160–325 mg daily and β blockers should be administered indefinitely. Anticoagulants should be administered post-MI to patients unable to tolerate daily aspirin, to those with persistent atrial fibrillation, and to those with left ventricular thrombus. Nitrates, along with βblockers, should be used to treat angina pectoris. Angiotensin-converting enzyme inhibitors should be administered after MI to patients who have congestive heart failure, an anterior MI, or a left ventricular ejection fraction of =40%. There are no class I indications for the use of calcium channel blockers after MI. Complex ventricular arrhythmias should be treated with βblockers. Persons with life-threatening ventricular tachycardia or ventricular fibrillation or who are at very high risk for sudden cardiac death after MI should receive an automatic implantable cardioverter-defibrillator. There are no class I indications for the use of hormonal therapy in postmenopausal women after MI. Indications for coronary revascularization after MI in older individuals are prolongation of life and relief of unacceptable symptoms despite optimal medical management. 相似文献
105.
In this retrospective follow-up study, the authors examined the association between race and the receipt of cardiology care in 1062 Medicare beneficiaries 65 years of age and older who were hospitalized with heart failure. The primary outcome measure was receipt of care from a cardiologist (via admission or consultation). Using logistic regression analyses, crude and adjusted odds ratios (OR) and 95% confidence intervals (95%CI) of receipt of cardiology care were estimated for nonwhite versus white patients. Two hundred (19%) patients were nonwhites and 483 (46%) patients received care from cardiologists. Proportion of patients receiving cardiology care was lower among nonwhite patients (35% versus 48% among whites; P = 0.001), and nonwhite race was associated with a lower odds of receiving cardiology care (crude OR = 0.57; 95%CI = 0.42-0.79). After adjustment for various patient characteristics and process-of-care variables, the magnitude and precision of the association between nonwhite race and a lower odds of receiving care from a cardiologist remained unchanged (adjusted OR = 0.43; 95% CI = 0.30-0.62). These findings suggest that nonwhite elderly hospitalized heart failure patients are less likely to be cared for by cardiologists. 相似文献
106.
Sinha N Yalamanchili K Sukhija R Aronow WS Fleisher AG Maguire GP Lehrman SG 《Cardiology in review》2005,13(1):46-49
We investigated the role of the standard 12-lead electrocardiogram (ECG) to improve the pretest probability of pulmonary embolism before performing computed tomographic (CT) pulmonary angiography. A retrospective chart analysis was performed on patients who underwent CT pulmonary angiography at a tertiary care hospital during a 30-month period. Comparison of 15 ECG parameters was made between those with CT pulmonary angiograms positive for pulmonary embolism and a matched control group with negative CT pulmonary angiograms. Data were analyzed by chi-squared tests and logistic regression. Sinus tachycardia (39% vs. 24%, P <0.01), an S1 Q3 T3 pattern (12% vs. 3%, P <0.01), atrial tachyarrhythmias (15% vs. 4%, P <0.005), a Q wave in lead III (40% vs. 26%, P <0.02), and a Q3 T3 pattern (8% vs. 1%, P <0.02) were the findings significantly associated with pulmonary embolism. We conclude that 1) standard 12-lead ECG findings can increase the pretest probability of pulmonary embolism before performing CT pulmonary angiography; and that 2) the ECG findings have relatively low likelihood ratios to have clinical use. 相似文献
107.
Samuel Butman P. A. N. Chandraratna Norah Milne Harold Olson Kenneth Lyons Wilbert S. Aronow 《Catheterization and cardiovascular interventions》1982,8(3):243-252
Twenty-four patients with mitral valve prolapse underwent cardiac catheterization, exercise testing, and exercise 201thallium scintigraphy. Of 10 patients with coronary artery disease, six had abnormal scintigrams. Two of these six had exercise-induced reversible defects, two had defects that persisted during redistribution, and two had both reversible and persistent defects. Of 14 patients with normal coronary arteries, five had negative scintigrams. Of the remaining nine patients, two had exercise-induced defects, and seven (50%) had defects involving the inferior or posterior wall that persisted during redistribution. Possible mechanisms for this latter finding are discussed. In contrast to previous reports, exercise 201thallium scintigraphy was not entirely successful in identifying patients with coronary artery disease in our patients with mitral valve prolapse. 相似文献
108.
Myocardial resistance assessed by guidewire-based pressure-temperature measurement: in vitro validation. 总被引:1,自引:0,他引:1
Wilbert Aarnoudse Petra van den Berg Frans van de Vosse Maartje Geven Marcel Rutten Mark Van Turnhout William Fearon Bernard de Bruyne Nico Pijls 《Catheterization and cardiovascular interventions》2004,62(1):56-63
By injecting a few cubic centimeters of saline into the coronary artery and using thermodilution principles, mean transit time (T(mn)) of the injectate can be calculated and is inversely proportional to coronary blood flow. Because microvascular resistance equals distal coronary pressure (P(d)) divided by myocardial flow, the product P(d). T(mn) provides an index of myocardial resistance (IMR). In this in vitro study in a physiologic model of the coronary circulation, we compared IMR to true myocardial resistance (TMR) at different degrees of myocardial resistance and at different degrees of epicardial stenosis. Absolute blood flow was varied from 42 to 203 ml/min and TMR varied from 0.39 to 1.63 dynes. sec/cm(5). Inverse mean transit time correlated well to absolute blood flow (R(2) = 0.93). Furthermore, an excellent correlation was found between IMR and TMR (R(2) = 0.94). IMR was independent on the severity of epicardial stenosis and thus specific for myocardial resistance. Thus, using one single guidewire, both fractional flow reserve and IMR can be measured simultaneously as indexes of epicardial and microvascular disease, respectively, enabling separate assessment of both coronary arterial and microvascular disease. 相似文献
109.
Aronow WS 《Nature clinical practice. Cardiovascular medicine》2008,5(9):514-515
Commentaries and debates at national medical meetings have fuelled the controversy about treatment of hypertension in patients aged 80 years and older. A double-blind, randomized, placebo-controlled trial was, therefore, indicated to settle the dispute about whether antihypertensive drug therapy is efficacious or harmful in these patients. Results from HYVET (Hypertension in the Very Elderly Trial) showed that, at 2-year follow-up, antihypertensive drug therapy with indapamide, plus perindopril if needed, reduced fatal or nonfatal stroke by 30%, fatal stroke by 39%, all-cause mortality by 21%, cardiovascular death by 23%, and heart failure by 64%. These results indicate that hypertensive patients aged 80 years and older should be treated with antihypertensive drugs. 相似文献
110.
Gerhardus J. Tijhuis Aeilko H. Zwinderman Johanna M. W. Hazes Wilbert B. Van Den Hout Ferdinand C. Breedveld Theodora P. M. Vliet Vlieland 《Arthritis care & research》2002,47(5):525-531