全文获取类型
收费全文 | 44906篇 |
免费 | 7489篇 |
国内免费 | 295篇 |
专业分类
耳鼻咽喉 | 537篇 |
儿科学 | 1388篇 |
妇产科学 | 1692篇 |
基础医学 | 2958篇 |
口腔科学 | 2275篇 |
临床医学 | 8780篇 |
内科学 | 10042篇 |
皮肤病学 | 1068篇 |
神经病学 | 3854篇 |
特种医学 | 1137篇 |
外国民族医学 | 5篇 |
外科学 | 5715篇 |
综合类 | 1222篇 |
现状与发展 | 2篇 |
一般理论 | 19篇 |
预防医学 | 5246篇 |
眼科学 | 1181篇 |
药学 | 2315篇 |
1篇 | |
中国医学 | 379篇 |
肿瘤学 | 2874篇 |
出版年
2024年 | 255篇 |
2023年 | 1587篇 |
2022年 | 1049篇 |
2021年 | 1818篇 |
2020年 | 1887篇 |
2019年 | 1377篇 |
2018年 | 2610篇 |
2017年 | 2445篇 |
2016年 | 2565篇 |
2015年 | 2562篇 |
2014年 | 3121篇 |
2013年 | 3277篇 |
2012年 | 2789篇 |
2011年 | 3052篇 |
2010年 | 2417篇 |
2009年 | 2440篇 |
2008年 | 2144篇 |
2007年 | 1808篇 |
2006年 | 1735篇 |
2005年 | 1497篇 |
2004年 | 1471篇 |
2003年 | 1279篇 |
2002年 | 1105篇 |
2001年 | 732篇 |
2000年 | 412篇 |
1999年 | 515篇 |
1998年 | 530篇 |
1997年 | 458篇 |
1996年 | 466篇 |
1995年 | 338篇 |
1994年 | 240篇 |
1993年 | 264篇 |
1992年 | 245篇 |
1991年 | 216篇 |
1990年 | 147篇 |
1989年 | 173篇 |
1988年 | 160篇 |
1987年 | 107篇 |
1986年 | 139篇 |
1985年 | 108篇 |
1984年 | 93篇 |
1983年 | 88篇 |
1982年 | 88篇 |
1981年 | 78篇 |
1980年 | 79篇 |
1979年 | 63篇 |
1978年 | 71篇 |
1977年 | 59篇 |
1975年 | 51篇 |
1973年 | 58篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
41.
SARAH VOOGHT BSc RGN ALISON RICHARDSON PhD MSc RGN 《European journal of cancer care》1996,5(4):217-224
Cancer patients are increasingly being cared for in the community. However, the role of the community oncology nurse specialist (CONS) remains a rare appointment in the United Kingdom. There is little research evidence to substantiate the view that this is a worthwhile and effective role. This study aimed to explore the role of one CONS using a qualitative case study approach. The sample consisted of the CONS, seven patients, no relatives and five community nurses. Semi-structured interviews were used to elicit the view of these participants. In addition, documents containing details of the CONS's work to date were reviewed. A number of the CONS's role components were identified by the different respondent groups. Five themes were identified within the data collected: functions of the CONS, communication between the CONS and other health care professionals, structural and organizational factors, characteristics of the service and benefits to patients and their families. Furthermore, all respondent groups were positive about the service offered by the CONS, and felt that the role was valuable. Some negative features were identified and these were concerned with organizational aspects of the service. The findings suggest the need for further research and evaluation in this area. 相似文献
42.
David A Todd MSc PhD John Kennedy FRACO † Sharyn Roberts RN Jane Watts RN Kim Psaila RN BApplSc Elizabeth John MD FRACP 《Clinical & experimental ophthalmology》1994,22(1):19-23
From January 1986 to December 1991 we examined the eyes of 206 infants born at Westmead Hospital, Neonatal Intensive Care Unit who were less than 29 weeks' gestation at birth to determine the incidence of retinopathy of prematurity. Eighty-five infants (41.3%) had no retinopathy of prematurity (ROP) in either eye, 82 infants had stages 1 or 2 ROP (39.8%), 29 had stage 3 ROP (14.1%) and 11 had stage 4 ROP (5.3%). Of these, cryotherapy was performed in 18; six now have bilateral retinal detachment and are blind The more severe stages of ROP were significantly associated with an increase in the number of days of oxygen supplementation, an increase in the number of days of mechanical ventilation and the presence of patent ductus arteriosus. Infants receiving steroids for mechanical ventilator dependence had a significantly greater chance of requiring cryotherapy (11 or 22 receiving steroids versus seven of 43 without steroids; P < 0.01). 相似文献
43.
医院综合效益评价案例分析 总被引:2,自引:0,他引:2
西南地区医院综合效益评价课题组 《中国医院管理》1994,14(2):32-35
运用层次分析法建立了医院综合效益评价指标体系,开发了医院综合效益九型评价图,用于显著评价结果。在此基础上进行了3个案例的评价分析。论述了通过对西南地区27所医院综合效益4年多的追踪分析所发现的共性问题,并提出了相应的管理对策。 相似文献
44.
Gregor McWalter MA MSc Hugh Toner MA DipCouns MSc CPsychol Alison Corser BSc MPhil CPsychol Jenny Eastwood MBChB DipSocMed FRCPsych Mary Marshall MA DSA DASS Tony Turvey BSc MAppSci CPsychol 《Health & social care in the community》1994,2(4):213-219
The concept of need and the practice of needs assessment are both subject to a wide range of interpretations, to the likely detriment of individual assessments and to multidisciplinary working. Clear definition is important for individual assessment, for the development of multidisciplinary tools and in gathering planning information. The concept of need is clarified, firstly by distinguishing between need and the difficulties that engender it, and secondly through a taxonomy of need. These assist clear definitions of both need and needs assessment when linked with a consideration of the current help a person receives and a specification of the type of help required by a person to meet their needs. Such definitions have implications for the role of needs assessment in individual assessment, service evaluation, service management and planning and in the development of multidisciplinary needs assessment tools. 相似文献
45.
46.
47.
Neil Scott Gordon MSc Dip Coun Dip N Cert Ed RCNT RNT RMN Peter Wimpenny RGN BSc Cert Ed RNT 《Journal of advanced nursing》1996,23(3):479-486
This paper, written by two male nurse teachers, describes and analyses their experience of working in a nurse education culture permeated by the philosophy of business management The introduction of business management practices to nurse education is discussed as a reflection of the current political hegemony of market forces and individualism The authors discuss the implications for nurse teachers of being continually exposed to these politically motivated forces which increasingly provide the paradigm for service developments within the United Kingdom health services In discussing the impact of this exposure it is argued that at the personal level individual teachers are experiencing a degree of apathy and personal dissonance which undermines their professional value system, resulting in emotional distress and a crisis of identity It provides a critical reflection on the way organizational dynamics and power relations influence the subjective sense-making of individuals The authors use a multiplicity of perspectives, including those provided by individual psychology, power relations, feminism and personhood, to argue for the need to develop an alternative paradigm which is characterized by the valuing of individual persons, empathic sensitivity and the fostering of creativity been important to us from a personal and professional 相似文献
48.
49.
50.
Leeta Alison Green Khoi Nguyen Bijan Berenji Meera Iyer Eileen Bauer Jorge R Barrio Mohammad Namavari Nagichettiar Satyamurthy Sanjiv S Gambhir 《Journal of nuclear medicine》2004,45(9):1560-1570
Reporter probe 9-(4-18F-fluoro-3-[hydroxymethyl]butyl)guanine (18F-FHBG) and reporter gene mutant herpes simplex virus type 1 thymidine kinase (HSV1-sr39tk) have been used for imaging reporter gene expression with PET. Current methods for quantitating the images using the percentage injected dose per gram of tissue do not distinguish between the effects of probe transport and subsequent phosphorylation. We therefore investigated tracer kinetic models for 18F-FHBG dynamic microPET data and noninvasive methods for determining blood time-activity curves in an adenoviral gene delivery model in mice. METHODS: 18F-FHBG (approximately 7.4 MBq [approximately 200 microCi]) was injected into 4 mice; 18F-FHBG concentrations in plasma and whole blood were measured from mouse heart left ventricle (LV) direct sampling. Replication-incompetent adenovirus (0-2 x 10(9) plaque-forming units) with the E1 region deleted (n = 8) or replaced by HSV1-sr39tk (n = 18) was tail-vein injected into mice. Mice were dynamically scanned using microPET (approximately 7.4 MBq [approximately 200 microCi] 18F-FHBG) over 1 h; regions of interest were drawn on images of the heart and liver. Serial whole blood 18F-FHBG concentrations were measured in 6 of the mice by LV sampling, and 1 least-squares ratio of the heart image to the LV time-activity curve was calculated for all 6 mice. For 2 control mice and 9 mice expressing HSV1-sr39tk, heart image (input function) and liver image time-activity curves (tissue curves) were fit to 2- and 3-compartment models using Levenberg-Marquardt nonlinear regression. The models were compared using an F statistic. HSV1-sr39TK enzyme activity was determined from liver samples and compared with model parameter estimates. For another 3 control mice and 6 HSV1-sr39TK-positive mice, the model-predicted relative percentage of metabolites was compared with high-performance liquid chromatography analysis. RESULTS: The ratio of 18F-FHBG in plasma to whole blood was 0.84 +/- 0.05 (mean +/- SE) by 30 s after injection. The least-squares ratio of the heart image time-activity curve to the LV time-activity curve was 0.83 +/- 0.02, consistent with the recovery coefficient for the partial-volume effect (0.81) based on independent measures of heart geometry. A 3-compartment model best described 18F-FHBG kinetics in mice expressing HSV1-sr39tk in the liver; a 2-compartment model best described the kinetics in control mice. The 3-compartment model parameter, k3, correlated well with the HSV1-sr39TK enzyme activity (r2 = 0.88). CONCLUSION: 18F-FHBG equilibrates rapidly between plasma and whole blood in mice. Heart image time-activity curves corrected for partial-volume effects well approximate LV time-activity curves and can be used as input functions for 2- and 3-compartment models. The model parameter k3 from the 3-compartment model can be used as a noninvasive estimate for HSV1-sr39TK reporter protein activity and can predict the relative percentage of metabolites. 相似文献