全文获取类型
收费全文 | 16876篇 |
免费 | 877篇 |
国内免费 | 152篇 |
专业分类
耳鼻咽喉 | 125篇 |
儿科学 | 425篇 |
妇产科学 | 448篇 |
基础医学 | 1937篇 |
口腔科学 | 265篇 |
临床医学 | 1237篇 |
内科学 | 4345篇 |
皮肤病学 | 384篇 |
神经病学 | 1712篇 |
特种医学 | 560篇 |
外科学 | 2880篇 |
综合类 | 44篇 |
一般理论 | 1篇 |
预防医学 | 640篇 |
眼科学 | 211篇 |
药学 | 990篇 |
中国医学 | 36篇 |
肿瘤学 | 1665篇 |
出版年
2024年 | 20篇 |
2023年 | 138篇 |
2022年 | 314篇 |
2021年 | 473篇 |
2020年 | 274篇 |
2019年 | 361篇 |
2018年 | 433篇 |
2017年 | 319篇 |
2016年 | 427篇 |
2015年 | 476篇 |
2014年 | 609篇 |
2013年 | 820篇 |
2012年 | 1214篇 |
2011年 | 1153篇 |
2010年 | 763篇 |
2009年 | 623篇 |
2008年 | 1043篇 |
2007年 | 1077篇 |
2006年 | 999篇 |
2005年 | 971篇 |
2004年 | 922篇 |
2003年 | 748篇 |
2002年 | 703篇 |
2001年 | 284篇 |
2000年 | 296篇 |
1999年 | 231篇 |
1998年 | 155篇 |
1997年 | 124篇 |
1996年 | 132篇 |
1995年 | 106篇 |
1994年 | 108篇 |
1993年 | 77篇 |
1992年 | 166篇 |
1991年 | 155篇 |
1990年 | 133篇 |
1989年 | 110篇 |
1988年 | 102篇 |
1987年 | 97篇 |
1986年 | 81篇 |
1985年 | 76篇 |
1984年 | 99篇 |
1983年 | 65篇 |
1982年 | 42篇 |
1981年 | 37篇 |
1980年 | 34篇 |
1979年 | 47篇 |
1978年 | 36篇 |
1977年 | 21篇 |
1976年 | 30篇 |
1974年 | 20篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
31.
Functional decline in frail community-dwelling stroke patients 总被引:1,自引:0,他引:1
F. Landi G. Onder M. Cesari V. Zamboni A. Russo C. Barillaro R. Bernabei 《European journal of neurology》2006,13(1):17-23
Patients who suffer a stroke event are at high risk of functional decline after the post-acute rehabilitation period. The aim of the present study was the evaluation of factors associated with functional decline in a large sample of older patients with stroke living in the community. The study population consisted of all patients admitted to home care programs after a post-acute rehabilitation program--with at least 1 year of follow-up--in twenty-two Italian Home Health Agencies from 2000 to 2002 (n=1338). For the present study we selected 355 (26%) patients with diagnosis of stroke. After 1 year of in-home care program, 149 out of 355 stroke survivors (42%) had presented a worsening in the activities of daily living (ADL) scale score. In the final adjusted model, patients with cognitive impairment (OR 2.59, 95% CI, 1.45-4.64), pressure ulcer (OR 2.74, 95% CI, 1.45-5.18), urinary incontinence (OR 1.64, 95% CI, 1.01-3.29), or hearing impairment (OR 1.83, 95% CI, 1.02-3.29) were more likely to significantly decline in physical functioning after a period of 1 year in-home care program. Our study documents that functional decline of stroke patients was largely dependent on specific subjects' clinical characteristics. Three of four concomitant disabling conditions associated in our sample with functional decline--pressure ulcer, urinary incontinence, hearing--can be prevented and eventually treated or modified. Appropriate post-acute rehabilitation programs and adequate home care interventions focused on the prevention and treatment of these conditions might be correlated to better outcomes in older post-stroke patients. 相似文献
32.
M. Riva A. Salmaggi E. Marchioni A. Silvani G. Tomei L. Lorusso R. Merli F. Imbesi A. Russo 《Neurological sciences》2006,27(5):345-351
Abstract Epilepsy in high-grade glioma patients is a major concern, mainly as regards indications to treatment and best choice; toxicities,
and pharmocokinetic and pharmacodynamic interactions of drugs. All these generally unsolved problems complicate patients’
quality of life and interfere with the evaluation of response criteria in clinical trials. A prospective, multicentre data
collection on 132 adult newly diagnosed, histologically proven glioblastomas from 9 Lombardy hospitals collected in the same
database during a one-year period was recently published. From this database we report epidemiological and clinical characteristics
in epilepsy-symptomatic (31%) glioblastoma patients vs. the group with other presenting symptoms (69%). We analyse demographic
and clinico-radiological features, timing of onset and the course of seizures, and modalities of treatment in the two groups
of patients. No statistically significant differences were observed between the two groups as regards age, site of lesion(s),
extent of surgery and survival in relation to anticonvulsant treatment status or pharmacokinetic properties of drugs. 相似文献
33.
34.
35.
T. Stroffolini G. Manzillo R. De Sena E. Manzillo P. Pagliano M. Zaccarelli M. Russo M. Soscia G. Giusti 《European journal of epidemiology》1992,8(4):539-542
Typhoid fever is endemic in the Neapolitan area, where its yearly incidence rate largely exceeds the corresponding national figure. During the period from January to June, 1990, a matched case-control study was carried out in order to identify risk factors of the disease in this area; 51 subjects (mean age 27.2 years) with typhoid fever were compared with 102 controls matched with respect to age, sex and educational level. Consumption of raw shellfish was reported by 76.5% of the cases, as opposed to 19.6% of the controls (P < 0.01). Subjects who had eaten this food item had a 13.3-fold risk (C.I. 95% = 5.5 - 32.8) of contracting typhoid fever. In contrast, no risk was found to be associated with consumption of cooked shellfish, raw vegetables, ice-cream, non-potable water, or unpasteurized milk.The risk factor identified in this study shows that hazardous dietary habits and inadequate sewage treatment facilities, combined with lack of sanitation in the harvesting and marketing of shellfish, play a major role in the endemicity of typhoid fever in the Neapolitan area.Corresponding author. 相似文献
36.
The Authors briefly summarise their experience of using various types of mechanical staplers in abdominal and thoracic surgery with excellent results both in general and in terms of reducing operating times. 相似文献
37.
E. S. Dellon J. A. Galanko R. K. Medapalli M. W. Russo 《American journal of transplantation》2006,6(9):2183-2190
Because creatinine is heavily weighed in the MELD (model for end-stage liver disease) score, we sought to determine the impact of MELD-based organ allocation on outcomes after transplantation in the pre- and post-MELD eras, focusing on recipients over age 65 on dialysis prior to transplant. A total of 20 196 patients from the UNOS database were analyzed. Comparing the pre-MELD to MELD era, there was a 41% increase in patients on dialysis (p<0.0001), and a 117% increase in combined liver/kidney transplants (p<0.0001). In the pre-MELD era, 1-year patient survival in recipients greater and less than age 65 on dialysis who received liver transplant alone was 56.8% and 76.4%, respectively (p=0.13). In the MELD era these rates were 50.7% and 77.8% (p=0.04). In the pre-MELD era, 1-year patient survival in recipients greater and less than age 65 on dialysis who underwent combined liver/kidney transplantation was 25.0% and 83.2%, respectively (p=0.0002). In the MELD era, these rates were 67.0% and 82.5% (p=0.18). In conclusion, a greater proportion of patients in the MELD era are on dialysis prior to transplant, and more receive combined liver/kidney transplants compared with the pre-MELD era. Candidates over age 65 who are on dialysis at the time of transplant have decreased survival after isolated liver transplantation. 相似文献
38.
Mark W Russo 《Liver transplantation》2004,10(9):1097-1098
39.
40.
L Resta M Troia S Russo G A Colucci R Sabatini L Loiudice G Cagnazzo 《European journal of gynaecological oncology》1992,13(5):440-444
Several experiences induced us to consider genital HPV infection as an expression of a local immunodeficiency. The aim of our study was to research the effect of immunotherapy on the lymphocyte subpopulations and Langerhans cells in vulvar condyloma. Twenty women with persistent vulvar condylomata, treated with 2,000,000 IU/die of beta-interferon for 15 days, were submitted to vulvar biopsy before and 2-5 months after medical treatment. The frozen sections obtained were assayed with the following monoclonal antibodies: OKT 4 (T helper lymphocytes), OKT 8 (T suppressor lymphocytes), OKB 7 (B lymphocytes) and S-100 protein (Langerhans cells). Using a morphometric evaluation, the average number of both intraepithelial and stromal lymphocyte subsets and of the intraepithelial Langerhans cells was assessed. In all the biopsies preceeding the medical treatment we found a low number of T helper lymphocytes both in the epithelium and stroma, with inversion of T4/T8 lymphocyte ratio and rare presence of Langerhans cells. In patients with a good therapeutic response (50-100% of condyloma reduction) we observed an increase in intraepithelial T4 lymphocytes and a decrease in both intraepithelial and stromal T8 lymphocytes. In cases with persistent disease after therapy, the histological pattern was similar to that observed in the first biopsy, with the exception of a significant increase in the average number of Langerhans cells. Our data correlate the clinical response to the immunotherapy with the histology of lymphocyte subsets in the vulvar condylomata. The increase in Langerhans cells observed in patients with negative response may be interpreted with a probable inability of these cells to promote the immune reaction. 相似文献