全文获取类型
收费全文 | 31568篇 |
免费 | 2729篇 |
国内免费 | 99篇 |
专业分类
耳鼻咽喉 | 394篇 |
儿科学 | 678篇 |
妇产科学 | 386篇 |
基础医学 | 4378篇 |
口腔科学 | 760篇 |
临床医学 | 3766篇 |
内科学 | 6939篇 |
皮肤病学 | 592篇 |
神经病学 | 2896篇 |
特种医学 | 1007篇 |
外国民族医学 | 3篇 |
外科学 | 4521篇 |
综合类 | 417篇 |
现状与发展 | 1篇 |
一般理论 | 20篇 |
预防医学 | 2666篇 |
眼科学 | 641篇 |
药学 | 2094篇 |
中国医学 | 78篇 |
肿瘤学 | 2159篇 |
出版年
2023年 | 173篇 |
2022年 | 353篇 |
2021年 | 668篇 |
2020年 | 458篇 |
2019年 | 717篇 |
2018年 | 827篇 |
2017年 | 603篇 |
2016年 | 630篇 |
2015年 | 765篇 |
2014年 | 989篇 |
2013年 | 1385篇 |
2012年 | 2119篇 |
2011年 | 2306篇 |
2010年 | 1147篇 |
2009年 | 1092篇 |
2008年 | 1819篇 |
2007年 | 1864篇 |
2006年 | 1749篇 |
2005年 | 1829篇 |
2004年 | 1645篇 |
2003年 | 1509篇 |
2002年 | 1537篇 |
2001年 | 499篇 |
2000年 | 524篇 |
1999年 | 468篇 |
1998年 | 347篇 |
1997年 | 316篇 |
1996年 | 227篇 |
1995年 | 237篇 |
1994年 | 176篇 |
1993年 | 171篇 |
1992年 | 329篇 |
1991年 | 321篇 |
1990年 | 299篇 |
1989年 | 275篇 |
1988年 | 265篇 |
1987年 | 261篇 |
1986年 | 279篇 |
1985年 | 276篇 |
1984年 | 231篇 |
1983年 | 198篇 |
1982年 | 178篇 |
1981年 | 193篇 |
1980年 | 158篇 |
1979年 | 161篇 |
1978年 | 151篇 |
1976年 | 115篇 |
1975年 | 115篇 |
1974年 | 116篇 |
1973年 | 129篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
102.
Regional anaesthesia provides many advantages and can be practised safely in ambulatory surgery. It provides better postoperative pain control, avoids many complications associated with general anaesthesia and shortens recovery time. However, extra time required, associated complications and acceptance of patients are the factors of concern in practising regional anaesthesia in an ambulatory setting. This review will discuss various regional anaesthesia techniques suitable for outpatients. 相似文献
103.
D. Peres-Bota H. Rodriguez-Villalobos G. Dimopoulos C. Melot J.-L. Vincent 《Clinical microbiology and infection》2004,10(6):550-555
The incidence, risk factors and prognostic factors for candidal infection were determined in a prospective study of 280 infected patients. Thirty-one (11%) patients were infected with Candida spp., sub-divided into 18 (58%) with C. albicans, and 13 (42%) with non-albicans spp. (six C. glabrata, three C. parapsilosis, and one each of C. krusei, C. tropicalis, C. guilliermondii and C. lusitaniae). Infection with Candida spp. was always associated with concurrent bacterial infection. By univariate logistic regression analysis, the degree of morbidity and the duration of mechanical ventilation were independent predictive factors for death, but infection with Candida spp., was not. Factors associated with Candida spp. infection were the degree of morbidity, intensive care unit length of stay, alterations of immune response, and the number of medical devices involved. By multivariate logistic regression analysis, the only independent risk factor for candidal infection was intensive care unit length of stay. 相似文献
104.
The immune response of Drosophila melanogaster 总被引:4,自引:0,他引:4
Summary: The response of the fruit fly Drosophila melanogaster to various microorganism infections relies on a multilayered defense. The epithelia constitute a first and efficient barrier. Innate immunity is activated when microorganisms succeed in entering the body cavity of the fly. Invading microorganisms are killed by the combined action of cellular and humoral processes. They are phagocytosed by specialized blood cells, surrounded by toxic melanin, or lysed by antibacterial peptides secreted into the hemolymph by fat body cells. During the last few years, research has focused on the mechanisms of microbial recognition by various pattern recognition receptors and of the subsequent induction of antimicrobial peptide expression. The cellular arm of the Drosophila innate immune system, which was somehow neglected, now constitutes the new frontier. 相似文献
105.
Efficacy and safety of xaliproden in amyotrophic lateral sclerosis: results of two phase III trials.
Vincent Meininger Gilbert Bensimon Walter R Bradley Benjamin Brooks Patrice Douillet Andrew A Eisen Lucette Lacomblez P Nigel Leigh Wim Robberecht 《Amyotrophic lateral sclerosis and other motor neuron disorders》2004,5(2):107-117
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal motor neuron disease. We carried out two randomized, double-blind, placebo-controlled, multi-centre, multi-national studies with xaliproden (a drug with neurotrophic effect) to assess drug efficacy and safety at two doses. Patients with clinically probable or definite ALS of more than 6 months and less than 5 years duration were randomly assigned to placebo, 1 mg or 2 mg xaliproden orally once daily as monotherapy in Study 1 (n=867); or to the same regimen with addition of riluzole 50 mg bid background therapy in Study 2 (n=1210 patients). The two primary endpoints were defined as: 1. Time to death, tracheostomy, or permanent assisted ventilation (DTP), and 2. Time to vital capacity (VC)<50% or DTP before (log-rank test) and after adjustment using a Cox proportional hazard model for prespecified prognostic factors. Secondary endpoints were rates of change of various functional measures. In Study 1, primary outcome measures did not reach statistical significance. For the 2 mg group, for time to VC<50% analysis (without DTP) a significant 30% RRR was obtained (95% confidence interval [CI]: 8.46, P=0.009). In Study 2, no significant results were obtained. However, there was a trend in favour of add-on 1 mg dose xaliproden vs. placebo (RRR 15% [-6.31, ns] for time to VC<50%; RRR 12% [CI: -6.27, ns] for time to VC<50% or DTP). Adjusted RR ratios were consistently more favourable for the xaliproden groups. Tolerability was good, and dose-dependent side effects were largely associated with the serotonergic properties of xaliproden. An effect of xaliproden on functional parameters, especially VC, was noted. Although this effect did not reach statistical significance, xaliproden had a small effect on clinically noteworthy aspects of disease progression in ALS. 相似文献
106.
107.
Attachment style, childhood adversity, and behavioral risk among young men who have sex with men. 总被引:2,自引:0,他引:2
Marya Viorst Gwadz Michael C Clatts Noelle R Leonard Lloyd Goldsamt 《The Journal of adolescent health》2004,34(5):402-413
PURPOSE: To examine relationships among childhood adversity, attachment style (one's core beliefs regarding the self and others), and the following risk behaviors and contexts among young men who have sex with men (YMSM): homelessness, daily substance use, participation in sex work, involvement in the criminal justice system, and being out of school or work. METHODS: Using a targeted sampling approach, we recruited 569 YMSM aged 17-28 years from natural venues in New York City including bars, clubs, parks, and bus stations. Youth completed a structured interview assessing lifetime and current risk and protective contexts and behavior. Data were analyzed using univariate and multivariate statistical methods, including hierarchical logistic regression. RESULTS: After controlling for demographic characteristics and childhood adversity, YMSM with a fearful attachment style were more likely to have been homeless (OR 2.93, 95% CI 1.65-5.18), to have participated in sex work (OR 2.35, 95% CI 1.44-3.85), to use substances daily (OR 2.79, 95% CI 1.29-6.03), to have been involved in the criminal justice system (OR 2.04, 95% CI 1.38-3.01), and to be out of school/work (OR 2.47, 95% CI 1.47-4.15). Three subgroups were particularly vulnerable: YMSM who identified as heterosexual, or bisexual, and/or transgender. CONCLUSIONS: A fearful attachment style contributes to some YMSM remaining outside of the protective systems of family, school, and work, and is associated with risky contexts where they are less likely to encounter prosocial peers and adults. Further, it is associated with risk behavior. Although gay-identified youth are generally found to have poor outcomes when compared with the general population of adolescents, in the present report, YMSM who identified as heterosexual were at particular risk. Attachment theory can guide interventions by informing how individuals experience relationships and manage developmental transitions. 相似文献
108.
Vincent DeAngelis 《American journal of orthodontics and dentofacial orthopedics》2003,124(4):19A-20A, author reply 20A
109.
Ultrasound of soft tissue abnormalities of the extremities 总被引:2,自引:0,他引:2
L M Vincent 《Radiologic clinics of North America》1988,26(1):131-144
Ultrasound may be the preferred initial diagnostic modality for the painful swollen extremity, the palpable extremity mass, and the injured extremity. The role of ultrasound in extremity soft tissue abnormalities, including muscle hemorrhage and injury, inflammatory processes, and soft tissue neoplasms, is the subject of this review. 相似文献
110.