全文获取类型
收费全文 | 101161篇 |
免费 | 6645篇 |
国内免费 | 771篇 |
专业分类
耳鼻咽喉 | 1141篇 |
儿科学 | 3022篇 |
妇产科学 | 2540篇 |
基础医学 | 13674篇 |
口腔科学 | 2506篇 |
临床医学 | 8454篇 |
内科学 | 21958篇 |
皮肤病学 | 2138篇 |
神经病学 | 9487篇 |
特种医学 | 3869篇 |
外国民族医学 | 23篇 |
外科学 | 14086篇 |
综合类 | 1703篇 |
一般理论 | 55篇 |
预防医学 | 6266篇 |
眼科学 | 1587篇 |
药学 | 8207篇 |
3篇 | |
中国医学 | 531篇 |
肿瘤学 | 7327篇 |
出版年
2023年 | 464篇 |
2022年 | 960篇 |
2021年 | 2094篇 |
2020年 | 1339篇 |
2019年 | 1865篇 |
2018年 | 2283篇 |
2017年 | 1771篇 |
2016年 | 1816篇 |
2015年 | 2148篇 |
2014年 | 2831篇 |
2013年 | 4046篇 |
2012年 | 5480篇 |
2011年 | 5679篇 |
2010年 | 3605篇 |
2009年 | 3138篇 |
2008年 | 4850篇 |
2007年 | 5035篇 |
2006年 | 4752篇 |
2005年 | 4504篇 |
2004年 | 4726篇 |
2003年 | 4565篇 |
2002年 | 4596篇 |
2001年 | 3750篇 |
2000年 | 3712篇 |
1999年 | 2996篇 |
1998年 | 1152篇 |
1997年 | 897篇 |
1996年 | 827篇 |
1995年 | 791篇 |
1994年 | 704篇 |
1993年 | 679篇 |
1992年 | 1826篇 |
1991年 | 1791篇 |
1990年 | 1525篇 |
1989年 | 1472篇 |
1988年 | 1338篇 |
1987年 | 1191篇 |
1986年 | 1196篇 |
1985年 | 1055篇 |
1984年 | 782篇 |
1983年 | 715篇 |
1982年 | 454篇 |
1981年 | 389篇 |
1979年 | 579篇 |
1978年 | 429篇 |
1975年 | 438篇 |
1974年 | 498篇 |
1973年 | 470篇 |
1972年 | 428篇 |
1971年 | 400篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
11.
12.
F. Giovanardi F. Nudo Q. Lai M. Garofalo A. Consolo E. Choppin De Janvry G.A. Arroyo Murillo P. Ursi D. Stabile F. Melandro P.B. Berloco R. Pretagostini L. Poli 《Transplantation proceedings》2019,51(1):128-131
Background
Arterial vascular anomalies in patients undergoing kidney transplantation (KT) are correlated with a higher incidence of early surgical complications, potentially causing graft loss. Arterial reconstruction allows patients to overcome these surgical challenges, thus minimizing the risk of poor outcomes. The aim of the present study is to retrospectively investigate the safety and effectiveness of the multiple arterial reconstruction technique with a Teflon patch in case of an unavailable aortic patch: to do so, surgical complications, graft function, and patient survival were evaluated.Methods
During the period January 2009 to August 2016, 202 adult deceased-donor KTs were performed at our center. Group A (n = 27; reconstruction of multiple arteries) and Group B (n = 175; control group) were compared.Results
No differences were observed between the 2 groups in terms of early postoperative course, with no vascular complication observed in Group A. No vascular patch infections were reported, nor longer cold ischemia time rates. Similarly, long-term survival rates were similar between the 2 groups.Conclusions
The Teflon-patch arterial reconstruction technique appears to be safe and effective, with an acceptable balance of benefits and potential risks of using a prosthetic material. Studies based on larger series are needed to further validate this approach. 相似文献13.
14.
David M. Presby Michael C. Rudolph Vanessa D. Sherk Matthew R. Jackman Rebecca M. Foright Kenneth L. Jones Julie A. Houck Ginger C. Johnson Janine A. Higgins P. Darrell Neufer Robert H. Eckel Paul S. MacLean 《Diabetes》2021,70(4):867
Moderate weight loss improves numerous risk factors for cardiometabolic disease; however, long-term weight loss maintenance (WLM) is often thwarted by metabolic adaptations that suppress energy expenditure and facilitate weight regain. Skeletal muscle has a prominent role in energy homeostasis; therefore, we investigated the effect of WLM and weight regain on skeletal muscle in rodents. In skeletal muscle of obesity-prone rats, WLM reduced fat oxidative capacity and downregulated genes involved in fat metabolism. Interestingly, even after weight was regained, genes involved in fat metabolism were also reduced. We then subjected mice with skeletal muscle lipoprotein lipase overexpression (mCK-hLPL), which augments fat metabolism, to WLM and weight regain and found that mCK-hLPL attenuates weight regain by potentiating energy expenditure. Irrespective of genotype, weight regain suppressed dietary fat oxidation and downregulated genes involved in fat metabolism in skeletal muscle. However, mCK-hLPL mice oxidized more fat throughout weight regain and had greater expression of genes involved in fat metabolism and lower expression of genes involved in carbohydrate metabolism during WLM and regain. In summary, these results suggest that skeletal muscle fat oxidation is reduced during WLM and regain, and therapies that improve skeletal muscle fat metabolism may attenuate rapid weight regain. 相似文献
15.
16.
17.
18.
19.