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91.
Regina Celia Fiorati Valeria Meirelles Carril Elui 《Revista latino-americana de enfermagem》2015,23(2):329-336
OBJECTIVE:
to analyze the socio-familial and community inclusion and social participation of people with disabilities, as well as their inclusion in occupations in daily life.METHOD:
qualitative study with data collected through open interviews concerning the participants'' life histories and systematic observation. The sample was composed of ten individuals with acquired or congenital disabilities living in the region covered by a Family Health Center. The social conception of disability was the theoretical framework used. Data were analyzed according to an interpretative reconstructive approach based on Habermas'' Theory of Communicative Action.RESULTS:
the results show that the socio-familial and community inclusion of the study participants is conditioned to the social determinants of health and present high levels of social inequality expressed by difficult access to PHC and rehabilitation services, work and income, education, culture, transportation and social participation.CONCLUSION:
there is a need to develop community-centered care programs in cooperation with PHC services aiming to cope with poverty and improve social inclusion. 相似文献92.
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Antonia Valeria Borraccino Francesca Celiberto Maria Pricci Bruna Girardi rea Iannone Maria Rendina Enzo Ierardi Alfredo Di Leo Giuseppe Losurdo 《World journal of gastroenterology : WJG》2022,28(45):6356-6362
When several Helicobacter pylori eradication treatments fail, guidelines recommend a cultured guided approach; however, culture is not widely available. Therefore, a rifabutin based regimen could be the best solution. Rifabutin indeed shows a low rate of antibiotic resistance. Rifabutin is generally used in combination with amoxicillin in a triple therapy, with eradication rates about 80% in third-line regimens. The ideal duration of this therapy should range between 10 and 12 d. Combinations with antibiotics other than amoxicillin have demonstrated even better results, such as vonoprazan, which is a type of novel acid suppressor drug. Finally, a new formulation of triple therapy in a single capsule is under investigation, which is a field that deserves further investigation. Some notes of caution about rifabutin should be mentioned. This drug is used to treat tuberculosis or atypical mycobacteria; therefore, before starting a rifabutin-based eradication regimen, Mycobacterium tuberculosis infection should be thoroughly tested, since its use could promote the development of antibiotic resistance, thus affecting its effectiveness against Koch’s bacillus. Additionally, some serious side effects must be evaluated before starting any rifabutin-based therapy. Adverse effects include fever, nausea, vomiting and bone marrow suppression. For this reason, full blood count surveillance is required. 相似文献
95.
Pasquale Vergara MD PhD Carlo Pignalberi MD Ennio C. Pisanò MD Giampiero Maglia MD Paolo Della Bella MD Gabriele Zanotto MD Saverio Iacopino MD Francesco Solimene MD Valeria Calvi MD Massimiliano Marini MD Massimo Giammaria MD Mauro Biffi MD Giovanni Rovaris MD Fabrizio Caravati MD Fabio Quartieri MD Antonio Curnis MD Antonio Rapacciuolo MD PhD Gaetano Senatore MD Stefano Pedretti MD Davide Saporito MD Antonio Dello Russo MD Vincenzo E. Santobuono MD PhD Patrizia Pepi MD Antonio Duca MD Matteo Baroni MD Giulio Falasconi MD Daniele Giacopelli MSc Alessio Gargaro MSc Antonio D'Onofrio MD 《Journal of cardiovascular electrophysiology》2021,32(9):2528-2535
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Role of gamma-glutamyl transferase activity in patients with chronic hepatitis C virus infection 总被引:2,自引:0,他引:2
Silva IS Ferraz ML Perez RM Lanzoni VP Figueiredo VM Silva AE 《Journal of gastroenterology and hepatology》2004,19(3):314-318
BACKGROUND: Increased serum gamma-glutamyl transferase (GGT) levels are frequently observed in chronic hepatitis C virus (HCV) infection. However, the significance of this finding remains unclear. The purpose of the present paper was to assess the relationship between GGT levels and clinical, biochemical and histological features in chronic HCV-infected carriers. METHODS: Patients with a liver biopsy presenting anti-HCV and HCV-RNA were evaluated. Age, gender, risk factors of transmission, serum alanine aminotransferase (ALT), GGT and alkaline phosphatase (ALP) levels and histological features were assessed in all. Data were analyzed statistically by the chi2 test and multivariate logistic regression analysis. RESULTS: Among 201 patients studied, elevated GGT levels and bile duct damage were observed in 48% and 35% of them, respectively. No association was seen between GGT level and bile duct damage or between GGT level and hepatic steatosis. Initially, age >40 years (P=0.007), elevated ALT (P=0.01), grading of inflammatory activity (P=0.004) and staging of fibrosis (P<0.001) were found to be associated with elevated GGT levels. After multivariate regression analysis, histology grading 3 and 4 inflammation activity (P=0.01) and staging 3 and 4 fibrosis (P=0.01) remained independently associated with elevated GGT level. CONCLUSIONS: A significant number of patients with chronic HCV infection had elevated serum GGT levels. Furthermore, this enzyme seemed to be useful as an indirect marker of more advanced liver disease in chronic hepatitis C. 相似文献
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Ana Paula H. Yokoyama Silvano Wendel Carolina Bonet-Bub Roberta M. Fachini Ana Paula F. Dametto Fernando Blumm Valeria F. Dutra Gabriela T. P. Candelaria Araci M. Sakashita Rafael Rahal Guaragna Machado Rita Fontão-Wendel Nelson Hamerschlak Ruth Achkar Murillo Santucci Cesar Assunção Patrícia Scuracchio Victor Nudelman Laerte Pastore João R. R. Pinho Mirian Dal Ben Roberto Kalil Filho Alexandre R. Marra Mariane T. Amano Esper G. Kallás Alfredo Salim Helito Carlos Roberto Ribeiro de Carvalho Danielle Bastos Araujo Edison Luiz Durigon Anamaria A. Camargo Luiz V. Rizzo Luiz F. L. Reis Jose M. Kutner 《Transfusion》2021,61(8):2295-2306