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991.
M. Patrick Lowe Saurabh Kumar Peter R. Johnson Scott A. Kamelle Donald H. Chamberlain Todd D. Tillmanns 《Journal of robotic surgery》2010,4(2):109-115
The primary aim of this article is to report the outcomes of octogenarians and nonagenarians who have undergone robotic surgery
for endometrial cancer. A multi-institutional research consortium was created to evaluate the utility of robotics for gynecologic
surgery (benign and malignant). IRB approval was obtained at each institution. A multi-institutional HIPPA compliant database
was then created and analyzed for all patients that underwent robotic-assisted surgery with staging for endometrial cancer
between the April 2003 and January 2009. In total, 395 patients were identified. A subset of patients between the ages of
80 and 95 years were then identified and analyzed for demographic data and perioperative outcomes. Twenty-seven patients in
this age group were identified who underwent robotic-assisted hysterectomy and staging. The median age was 84, and median
body mass index was 28. Comorbidities such as diabetes mellitus and hypertension were identified in 22 and 74% of patients,
respectively. Over one-half (56%) of the patients reported a prior abdominal surgery. Final pathological analysis demonstrated
that 88% of all patients had either Stage I or II disease. The median operative time was 192 min. The median estimated blood
loss was 50 cc, and the median lymph node count was 16. The median hospital stay was 1.0 day. The overall intraoperative and
postoperative complication rate was 7.4 and 33%, respectively. No patient received a blood transfusion. There was one conversion
to laparotomy (3.7%). A comparison of the outcomes of the elderly cohort to those of all patients in the database (control
group) revealed that there was no statistically significant difference between the groups in terms of operative time, blood
loss, hospital stay, nodal yield, or conversion rate. Intraoperative complications were statistically similar between the
groups; however, postoperative complications were significantly higher in the elderly cohort. We conclude that robotic surgery
is safe, feasible, and expands surgical options for octogenarians and nonagenarians diagnosed with endometrial cancer. Age
should not be considered a contraindication for robotic surgical management of patients with endometrial cancer. 相似文献
992.
Kate M Dunn 《BMC musculoskeletal disorders》2010,11(1):23
Background
Epidemiological studies have identified important causal and prognostic factors for back pain, but these frequently only identify a proportion of the variance, and new factors add little to these models. Recently, interest has increased in studying diseases over the life course, stimulated by the 1997 book by Kuh and Ben-Shlomo, a move accompanied by important conceptual and methodological developments. This has resulted in improvements in the understanding of other conditions like cardiovascular and respiratory disease. This paper aims to examine how conceptual frameworks from life course epidemiology could enhance back pain research. 相似文献993.
994.
Nawar M. Shara Elizabeth A. Carter Soleman Abu-Bader Antonio Deshields Ali Fokar Barbara V. Howard 《Current cardiovascular risk reports》2010,4(3):181-185
Cardiovascular disease (CVD) risk factor profiles of Arab Americans may differ from those of the majority ethnic groups in
the United States on which clinical practice guidelines are based. Reasons for these differences include genetic homogeneity
and both cultural and lifestyle factors that influence CVD risk. Therefore, appropriate therapeutic targets for effective
CVD prevention in Arab Americans need to be designed. However, research on Arab American health is sparse. For the cross-sectional
survey described in this article, a convenience sample of Arab Americans living in Washington, DC; Virginia; and Maryland
was recruited. Arab Americans in our sample had a higher prevalence of high cholesterol and lower prevalence of diabetes and
hypertension than the general population of the United States. High levels of smoking and a lack of physical activity were
also reported. Most participants (71%) reported a score of 15 and below on the Center for Epidemiologic Studies Depression
Scale, indicating no signs of clinical depression. Predictors of depression were compared in those born inside and outside
the United States. With the results from this survey, we have designed a cross-sectional study to begin in early 2010 to determine
the prevalence of CVD risk factors in Arab Americans which can be compared with the overall population of the United States. 相似文献
995.
Mora Murri Eduardo García-Fuentes José Manuel García-Almeida Lourdes Garrido-Sánchez María Dolores Mayas Rosa Bernal Francisco J. Tinahones 《Obesity surgery》2010,20(3):363-368
Background
The prevalence of morbid obesity has seen an increase in developed countries over recent years. Bariatric surgery is almost the only effective strategy for treating super morbidly obese patients. The objective of the study was to evaluate the effects of bariatric surgery on the evolution of the main variables related to diabetes and obesity, especially insulin resistance, parameters of oxidative stress, and inflammatory markers in the early stage after surgery. 相似文献996.
Hatice Bilge Nurdan Ozbek Murat Okutan Aydın Cakir Hilal Acar 《Japanese journal of radiology》2010,28(2):110-116
Purpose
High-energy photons are most commonly used in radiotherapy to treat cancer. Wedge filters are required to obtain homogeneous dose distribution in the patient. Different wedge filter types create different surface doses. In this study, the effect of the virtual and physical wedge filters on the surface and build-up region doses was examined for 6- and 18-MV high-energy photon beams. 相似文献997.
998.
Yasushi Rino Munetaka Masuda Norio Yukawa Hitoshi Murakami Ken Takata Tsutomu Hayashi Shin-ichi Suzuki Kei-ichiro Kasama Toshio Imada 《Esophagus》2010,7(1):71-74
In this report, we describe our traction suture technique of the pericardium for suspension of the heart without hemodynamic
instability to obtain excellent exposure in the abdominal-transhiatal approach (TH). Our technique is an application of deep
pericardium stitches for off-pump coronary artery bypass surgery. In detail, the left hepatic lobe is detached at its triangular
ligament from the diaphragm and is deflected to the right. Then, the tendinous portion of the diaphragm arching over the esophagus
is incised upward in the midline until the pericardium is exposed. Pericardial fatty tissue was dissected. Three U-shaped
sutures reinforced with a felt pledget are placed on the posterior aspect of the pericardium and diaphragm. A 15 Fr. flexible
catheter is placed over both ends of the suture to avoid damage of the adjacent organs. Finally, the sutures are fixed to
the drape of anterior wall of the patient to maintain good exposure. 相似文献
999.
Benjamin L. Predmore David J. Lefer 《Journal of cardiovascular translational research》2010,3(5):487-498
The physiological role of the gaseous signaling molecule hydrogen sulfide (H2S) was first realized in the mid-1990s with the work of Abe and Kimura. Since then, it has become evident that this endogenous
gas is extremely important in the homeostasis of the cardiovascular system and the pathogenesis of cardiovascular disease.
Several biotechnology companies have developed and are developing H2S-based therapeutic compounds, and there are ongoing clinical trials investigating the therapeutic potential of H2S. Several organic and chemical compounds that are known H2S donors have the potential to be developed into effective H2S-based therapeutic agents. This review will provide a historical and current perspective on the role(s) of H2S in the cardiovascular system and the current state of development and future outlook of H2S-based therapies for cardiovascular disease. 相似文献
1000.
Shelly Choo Guy Marti Manuel Nastai Jessie Mallalieu Michele A. Shermak 《Obesity surgery》2010,20(10):1422-1428