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排序方式: 共有2139条查询结果,搜索用时 15 毫秒
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Transoral laser microsurgery for oropharyngeal squamous cell carcinoma: A paradigm shift in therapeutic approach
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Mark D. Wilkie MRCS DO‐HNS Navdeep S. Upile MRCS DO‐HNS Andrew S. Lau MRCS DO‐HNS Stephen P. Williams MRCS Jon Sheard FRCPath Tim R. Helliwell FRCPath Max Robinson FRCPath Jennifer Rodrigues FRCA Krishna Beemireddy FRCA Huw Lewis–Jones FRCR Rebecca Hanlon FRCR David Husband FRCR Aditya Shenoy FRCR Nicholas J. Roland FRCS Shaun R. Jackson FRCS Fazilet Bekiroglu FRCS Sankalap Tandon FRCS Jeffrey Lancaster FRCS Terence M. Jones FRCS 《Head & neck》2016,38(8):1263-1270
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Albo ME Richter HE Brubaker L Norton P Kraus SR Zimmern PE Chai TC Zyczynski H Diokno AC Tennstedt S Nager C Lloyd LK FitzGerald M Lemack GE Johnson HW Leng W Mallett V Stoddard AM Menefee S Varner RE Kenton K Moalli P Sirls L Dandreo KJ Kusek JW Nyberg LM Steers W;Urinary Incontinence Treatment Network 《The New England journal of medicine》2007,356(21):2143-2155
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Matchock RL Mordkoff JT 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2007,178(2):228-239
The aim of the present study was to examine visual attention, especially the executive control functions that deal with conflict,
when participants were in a low arousal state shortly after a nighttime awakening. Fifteen participants spent four consecutive
nights at a laboratory and performed a flankers task using two levels of target-distractor spacing (0.75° and 1.50°) and three
trial types (compatible, incompatible, and neutral). The first night was a habituation night. For the next three nights, participants
went to sleep at 2300 hours and were then awakened at either 2400 hours (1-h sleep bout), 0300 hours (4-h sleep bout), or
0600 hours (7-h sleep bout) and were administered a flankers task and a self-report questionnaire that measured arousal level.
These testing times were counter-balanced across participants, and a 2100 hours (pre-sleep) flankers task was also randomly
assigned to be completed on one of the testing nights. Response time on neutral-flanker trials was increased if participants
were awakened from a sleep bout and was slowest at 0300 hours, appearing to parallel circadian body temperature. In contrast,
failures of selective attention, as indexed by the difference between compatible and incompatible trials, increased linearly
as a function of the length of the sleep bout. Compared to the 2100 hours pre-sleep condition, self-reported energy was lower
and Tiredness was higher after awakening from a sleep bout. Taken together, the current data suggest a dissociation between
the processes that perform a non-conflict task and the executive control of attention. Specifically, longer sleep bouts seem
to be associated with greater difficulty in inhibiting task-irrelevant information, perhaps due to a sleep inertia effect
affecting the anterior cingulate cortex. 相似文献
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Weingarten TN Watson JC Hooten WM Wollan PC Melton LJ Locketz AJ Wong GY Yawn BP 《Pain》2007,132(1-2):189-194
The Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS), an assessment tool to determine if pain is predominantly neuropathic, has not been validated in a community setting. Previously identified residents of Olmsted County, Minnesota, with chronic pain were recruited using a stratified randomization process to increase the frequency of neuropathic pain in the study sample. Subjects completed the S-LANSS in mailed and telephone formats, and underwent clinical assessment to determine if a component of their pain was neuropathic. Sensitivity and specificity of the S-LANSS as compared to the clinical assessment were determined. Two hundred and five subjects participated in the study. Eighty-three subjects (40%) had a positive S-LANSS score in the mailed, as did 59 of 173 (34%) in the telephone format, with little inter-subject difference in scores (p=0.57). Clinical assessment identified a component of neuropathic pain in 37% of the sample (75/205). Compared to clinical assessment, sensitivity and specificity in the mailed S-LANSS were 57% (95% CI, 46-69%) and 69% (95% CI, 61-77%), respectively, and in the telephone S-LANSS were 52% (95% CI, 39-64%) and 78% (95% CI, 68-85%), respectively. The sensitivity and specificity of the S-LANSS in both formats were lower than the initial S-LANSS validation study. Differences in survey format and subject population could account for these differences, suggesting that the S-LANSS is best suited as a screening tool and its use to determine the prevalence of neuropathic pain in population studies should be viewed cautiously. 相似文献
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Jacqueline Soraru Nicole Isbel Germaine Wong Patrick Toby Coates Murty Mantha Abu Abraham Rajiv Juneja Danny Hsu Fiona Brown Bhadran Bose David Mudge Robert Carroll Joshua Kausman Peter Hughes Thomas Barbour Anne Durkan Peter Mount Darren Lee Nicholas Larkins Dwarakanathan Ranganathan Wai H. Lim 《Nephrology (Carlton, Vic.)》2020,25(9):683-690
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