全文获取类型
收费全文 | 4081篇 |
免费 | 230篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 23篇 |
儿科学 | 101篇 |
妇产科学 | 62篇 |
基础医学 | 595篇 |
口腔科学 | 99篇 |
临床医学 | 311篇 |
内科学 | 986篇 |
皮肤病学 | 100篇 |
神经病学 | 250篇 |
特种医学 | 144篇 |
外科学 | 581篇 |
综合类 | 17篇 |
预防医学 | 191篇 |
眼科学 | 79篇 |
药学 | 405篇 |
中国医学 | 49篇 |
肿瘤学 | 342篇 |
出版年
2023年 | 30篇 |
2022年 | 60篇 |
2021年 | 71篇 |
2020年 | 53篇 |
2019年 | 62篇 |
2018年 | 83篇 |
2017年 | 67篇 |
2016年 | 66篇 |
2015年 | 90篇 |
2014年 | 99篇 |
2013年 | 154篇 |
2012年 | 261篇 |
2011年 | 289篇 |
2010年 | 138篇 |
2009年 | 123篇 |
2008年 | 229篇 |
2007年 | 253篇 |
2006年 | 251篇 |
2005年 | 265篇 |
2004年 | 268篇 |
2003年 | 217篇 |
2002年 | 238篇 |
2001年 | 84篇 |
2000年 | 88篇 |
1999年 | 71篇 |
1998年 | 61篇 |
1997年 | 38篇 |
1996年 | 34篇 |
1995年 | 30篇 |
1994年 | 47篇 |
1993年 | 29篇 |
1992年 | 37篇 |
1991年 | 46篇 |
1990年 | 37篇 |
1989年 | 29篇 |
1988年 | 38篇 |
1987年 | 39篇 |
1986年 | 38篇 |
1985年 | 27篇 |
1984年 | 37篇 |
1983年 | 18篇 |
1982年 | 16篇 |
1981年 | 11篇 |
1980年 | 13篇 |
1979年 | 20篇 |
1978年 | 14篇 |
1974年 | 7篇 |
1973年 | 8篇 |
1970年 | 7篇 |
1967年 | 9篇 |
排序方式: 共有4335条查询结果,搜索用时 15 毫秒
81.
Stephanie T.Kuwahara Shuwan Liu Andrew Chareunsouk Maxwell Serowoky Francesca V.Mariani 《骨研究(英文版)》2022,(1):20-30
Uncovering the molecular pathways that drive skeletal repair has been an ongoing challenge. Initial efforts have relied on in vitro assays to identify the key signaling pathways that drive cartilage and bone differentiation. While these assays can provide some clues, assessing specific pathways in animal models is critical. Furthermore, definitive proof that a pathway is required for skeletal repair is best provided using genetic tests. Stimulating the Hh(Hedgehog) pathway can promote cartilage ... 相似文献
82.
The speed of sound (SOS) is available as an index of elasticity. Using a combination of magnetic resonance imaging (MRI) and ultrasound, one can measure the SOS. In this study, we verified the accuracy of SOS measurements by using a combination of MRI and ultrasound. The accuracy of the thickness measurements was confirmed by comparison of the results obtained with use of MRI with those of a non-contact laser, and the accuracy of the calculated SOS values was confirmed by comparison of the results of the combined method and ultrasound measurements with the transmission method ex vivo. There was no significant difference between thickness measurements by MRI and those with the non-contact laser, and there was a significant linear correlation between SOS measurement results by use of the combined method and those by use of the transmission method. We also showed that the SOS values obtained agreed with those of previously published studies. 相似文献
83.
Martin Zydek Matthew Petitt June Fang-Hoover Barbara Adler Lawrence M. Kauvar Lenore Pereira Takako Tabata 《Viruses》2014,6(3):1346-1364
Human cytomegalovirus (HCMV) is the major viral cause of congenital infection and birth defects. Primary maternal infection often results in virus transmission, and symptomatic babies can have permanent neurological deficiencies and deafness. Congenital infection can also lead to intrauterine growth restriction, a defect in placental transport. HCMV replicates in primary cytotrophoblasts (CTBs), the specialized cells of the placenta, and inhibits differentiation/invasion. Human trophoblast progenitor cells (TBPCs) give rise to the mature cell types of the chorionic villi, CTBs and multi-nucleated syncytiotrophoblasts (STBs). Here we report that TBPCs are fully permissive for pathogenic and attenuated HCMV strains. Studies with a mutant virus lacking a functional pentamer complex (gH/gL/pUL128-131A) showed that virion entry into TBPCs is independent of the pentamer. In addition, infection is blocked by a potent human neutralizing monoclonal antibody (mAb), TRL345, reactive with glycoprotein B (gB), but not mAbs to the pentamer proteins pUL130/pUL131A. Functional studies revealed that neutralization of infection preserved the capacity of TBPCs to differentiate and assemble into trophospheres composed of CTBs and STBs in vitro. Our results indicate that mAbs to gB protect trophoblast progenitors of the placenta and could be included in antibody treatments developed to suppress congenital infection and prevent disease. 相似文献
84.
85.
86.
87.
88.
89.
Tadashi Nomura MD PhD Mika Nakasone MD Takako Okamoto MD Hirotaka Ejiri MD PhD Sayuri Osawa MD Kazunobu Hashikawa MD PhD Hiroto Terashi MD PhD 《Pediatric dermatology》2020,37(4):776-779
Infantile hemangioma (IH) is a benign vascular tumor that gradually involutes over several years. Rapidly involuting congenital hemangioma (RICH) is the relatively rare congenital vascular tumor that is fully grown at birth and does not undergo postnatal growth and involutes during the first year. However, after involution of both IH and RICH, some have severe sequelae, such as redundant skin or conspicuous scarring, requiring additional treatment. We present the case of a 6-year-old girl with a concave deformity due to subcutaneous atrophy, skin darkening, and altered skin texture of her left zygomatic region following involution of a hemangioma. We successfully treated this patient by transferring a dermal fat graft. This technique can be beneficial for atrophic sequelae after regression of a hemangioma and is easy to perform and cosmetically effective. 相似文献