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排序方式: 共有7139条查询结果,搜索用时 31 毫秒
51.
KLEPP K-I.; ULVIK R.J.; MATTHIESEN S.B.; HANNAN P.; JACOBS D.R. JR.; AARO L.E. 《European journal of public health》1993,3(1):38-42
The general public of the City of Bergen, Norway was Invitedto participate in a cholesterol screening programme in October1988. Participants received the results of the cholesterol screeningand nutritional information from trained health personnel. Ashort questionnaire was mailed to all 354 participants 12weeks after the initial cholesterol screening. In March 1990,all participants were invited to have their cholesterol levelsre-examined. Psychosocial factors believed to be predictiveof future serum cholesterol changes were assessed at baselinealong with demographic variables. The majority of participants(61%) reduced their cholesterol level from October 1988 to March1990, and the average reduction in cholesterol level for thetotal population was 4.0%. Baseline cholesterol levels, beingconfident of one's own ability to change one's diet (self-efficacy),seeing heart disease risk reduction as very important, and maritalstatus were factors that significantly predicted successfulcholesterol reduction 18 months later. 相似文献
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53.
Postoperative radiation therapy in the management of lung cancer 总被引:1,自引:0,他引:1
Postoperative radiation therapy for lung cancer is still controversial. In a 9-year period, 69 patients with non-oat-cell carcinoma of the lung (16% stage I, 26% stage II, and 58% stage III) received such therapy. The radiation dose was less than 5,000 cGy in 42 patients, 5,000-5,900 cGy in 16, and 6,000 cGy or more in 11; follow-up ranged from 24 to 64 months. Actuarial survival at 2 and 4 years was 50% and 16%, respectively, for squamous cell carcinoma, and 40% and 26% for adenocarcinoma. The 5-year survival for stages I, II, and III cancer was 29%, 17%, and 19%, respectively. Histologic findings and type of surgery did not affect survival, but the radiation dose apparently did. The 3-year survival for patients who received less than 6,000 cGy was 35%, compared with 73% for patients who received higher doses. In eight patients, treatment failed within the irradiated volume: all had received doses of less than 6,000 cGy, and the volume in three was judged to be inadequate. 相似文献
54.
Phil Tibbo C J de Gara Treena M Blake Carolyn Steinberg Brian Stonehocker 《Revue canadienne de psychiatrie》2002,47(6):562-567
OBJECTIVE: To examine the perceptions of intimidation in the psychiatric educational environment in Edmonton, Alberta. METHODS: We distributed a 7-point modified Likert scale questionnaire that included questions with respect to intimidation perceptions and experience in psychiatry during a 1-week period to all student interns on psychiatry rotations, residents, and teaching faculty in the 5 teaching hospitals in Edmonton. RESULTS: A total of 92 individuals responded, with response rates of 81% for faculty, 82% for residents, and 84% for students. Response rates did not differ among sites. While there were differences between site and group with respect to comparing the perceived intimidation in psychiatry with other specialties, respondents did not view psychiatry as worse than other specialties. Although, overall, women perceived intimidation as more prevalent at their sites than did men, the overall means reflect sites that are relatively free from intimidation. Faculty and student interns within sites, except for the university hospital, tended to disagree on management's approach to perceived intimidation. All groups, however, reported little personal experience and felt their sites had little tolerance for intimidators. CONCLUSIONS: Reported perceptions and personal experiences of intimidation within the psychiatric learning environment in Edmonton are low. 相似文献
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56.
A key DNA-protein interaction determines the function of the 5'URR enhancer in human papillomavirus type 11. 总被引:3,自引:0,他引:3
The 5' end of the upstream regulatory region (URR) of human papillomavirus type 11 (HPV-11) has enhancer function and binds cellular proteins. We have determined that one particular motif, a CCNGTNAC pair, is both necessary and sufficient for enhancer activity. This enhancement of expression can be competed in vivo by concatenated double-stranded oligonucleotides, indicating that protein-DNA binding is a requisite for enhancer activity. A 41-kDa protein, present in all epithelial cells assayed, binds to this enhancer motif. The 5'URR fragment functions as an enhancer both in primary keratinocytes from a variety of body sites and in fibroblasts. We conclude that tissue specificity is not a feature of this enhancer, and that the 41-kDa binding protein is ubiquitous. These data provide evidence that the 5'URR enhancer activity is dependent on only a few sequences and perhaps only one protein. 相似文献
57.
Evaluation of maternal plasma creatine kinase activity as a marker of abnormal early pregnancy 总被引:1,自引:0,他引:1
Zorn JR; Cherruau B; Abi-Rached F; Dehee A; Danoy X; Le Blond J; Ekindjian O 《Human reproduction (Oxford, England)》1997,12(11):2534-2537
We have tested the value of maternal plasma creatine kinase activity for
diagnosing ectopic pregnancies obtained after in-vitro fertilization and
embryo transfer. Plasma creatine kinase was assayed in 57 patients: 20
normal, 23 miscarriages and 14 ectopic pregnancies, for a total of 240
samples. All values were in the lower part of the normal range except only
one in a miscarrying patient. A statistically significant difference was
observed for a cut-off value of 45 IU/l between normal and ectopic
pregnancies. However, for this cut-off point, the measurement of plasma
creatine kinase activity had a sensitivity of 0.50 and a specificity of
0.76 for the diagnosis of ectopic pregnancy. The positive predictive value
was 0.69. Creatine kinase activity measurements are thus of no practical
value in this particular population, in which an early and specific marker
of ectopic implantation would be of paramount interest. The association of
human chorionic gonadotrophin (HCG) determinations and ultrasound scanning
of the pelvis still remain the best paraclinical support for an early
diagnosis of ectopic implantation.
相似文献
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60.
MARTIN J. BOHN JR JOYCE L. CARBONELL EDWIN I. MEGARGEE 《Criminal behaviour and mental health : CBMH》1995,5(1):14-33
This study investigated the applicability and utility of Megargee and Bohn's MMPI-based offender classification system in correctional mental health units (MHUs). Previous studies found that 11 MHU samples (n = 1723) had substantially more offenders classified in the more pathological MMPI types than did 21 samples (n = 5881) drawn from general male populations in US prisons. In this study of 63 severely disturbed felons, 43% belonged to the most pathological type (‘group How’). Comparing MHU patients with general offenders from the same IvfIvIPI types on staff ratings and case history variables, we found that the MHU patients were significantly poorer in adjustment. Within the MHU sample, there was no difference in case history variables or adjustment ratings between those in the most and least severe MMPI types. These findings differed from those of studies using less severely disturbed, more heterogeneous, MHU populations. It was concluded that, in settings in which the entire population is flagrantly disturbed, the MMPI-based system is more useful in screening potential admissions than it is in making meaningful distinctions among those already admitted. 相似文献