全文获取类型
收费全文 | 244篇 |
免费 | 13篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 9篇 |
基础医学 | 21篇 |
口腔科学 | 1篇 |
临床医学 | 31篇 |
内科学 | 61篇 |
皮肤病学 | 1篇 |
神经病学 | 13篇 |
特种医学 | 53篇 |
外科学 | 18篇 |
综合类 | 6篇 |
预防医学 | 12篇 |
眼科学 | 3篇 |
药学 | 33篇 |
肿瘤学 | 7篇 |
出版年
2022年 | 1篇 |
2020年 | 1篇 |
2019年 | 2篇 |
2018年 | 9篇 |
2017年 | 3篇 |
2016年 | 4篇 |
2015年 | 1篇 |
2014年 | 2篇 |
2013年 | 10篇 |
2012年 | 3篇 |
2011年 | 2篇 |
2010年 | 6篇 |
2009年 | 4篇 |
2008年 | 8篇 |
2007年 | 5篇 |
2006年 | 11篇 |
2005年 | 3篇 |
2004年 | 4篇 |
2003年 | 6篇 |
2002年 | 5篇 |
2001年 | 1篇 |
2000年 | 3篇 |
1999年 | 6篇 |
1998年 | 17篇 |
1997年 | 14篇 |
1996年 | 22篇 |
1995年 | 9篇 |
1994年 | 10篇 |
1993年 | 13篇 |
1992年 | 5篇 |
1991年 | 4篇 |
1990年 | 8篇 |
1989年 | 14篇 |
1988年 | 17篇 |
1987年 | 9篇 |
1986年 | 2篇 |
1985年 | 5篇 |
1984年 | 3篇 |
1983年 | 3篇 |
1982年 | 6篇 |
1981年 | 2篇 |
1980年 | 1篇 |
1977年 | 2篇 |
1975年 | 3篇 |
1926年 | 1篇 |
排序方式: 共有270条查询结果,搜索用时 296 毫秒
41.
This text approaches the necessary dialogue among different knowledge and considers the advances within Nursing in the search for consistence and clarity within the Nursing discipline. Towards this end, the text is based upon transdisciplinarity, intersectorality, complexity, and the interaction of different pairs in health and other areas, as well as the sustainance of scientific and technological space within Nursing. It argues perspectives that open possibilities for scientific and technological knowledge construction within a more responsible and mutual social commitment. The purpose of the paperis to amplify the aptitude for contextualization and globalize different knowledge, as well as transcend differences and peculiarities within the perspective of more qualitative policies which may overcome disciplinary barriers. 相似文献
42.
43.
44.
45.
人参皂甙诱导的造血细胞内信号传递途径的研究 总被引:13,自引:1,他引:12
目的探讨人参皂甙(GS)刺激造血祖细胞增殖有关的细胞内信号传递途径。方法采用Northern印迹杂交法、电泳带移动阻滞实验、抗体胶结合移动实验和紫外放射交联实验。结果NorthernBlot显示经GS诱导的人巨核细胞株CHRF288、Meg01和MO7e细胞的GATA2mRNA水平增高,分别是未经处理细胞的1.84,2.43和1.52倍。但GATA1mRNA表达水平低,且GS处理前后也无明显变化。电泳带移动阻滞实验提示GS诱导的细胞核内GATA转录调控蛋白与特定的DNA序列结合的活性增高。抗体胶结合移动实验证实与DNA结合的主要成分为GATA2蛋白,紫外放射交联实验确定该复合物的相对分子质量约为50×103,符合GATA2转录调控蛋白。结论GS诱导细胞内的信号传递途径与转录因子GATA2有关,GATA2有介导GS刺激造血细胞增殖的作用。 相似文献
46.
47.
Bense S Janusch B Schlindwein P Bauermann T Vucurevic G Brandt T Stoeter P Dieterich M 《Human brain mapping》2006,27(4):296-305
Looking at a moving pattern induces optokinetic nystagmus (OKN) and activates an assembly of cortical areas in the visual cortex, including lateral occipitotemporal (motion-sensitive area MT/V5) and adjacent occipitoparietal areas as well as ocular motor areas such as the prefrontal cortex, frontal, supplementary, and parietal eye fields. The aim of this functional MRI (fMRI) study was to investigate (1) whether stimulus direction-dependent effects can be found, especially in the cortical eye fields, and (2) whether there is a hemispheric dominance of ocular motor areas. In a group of 15 healthy subjects, OKN in rightward and leftward directions was visually elicited and statistically compared with the control condition (stationary target) and with each other. Direction-dependent differences were not found in the cortical eye fields, but an asymmetry of activation occurred in paramedian visual cortex areas, and there were stronger activations in the hemisphere contralateral to the slow OKN phase (pursuit). This can be explained by a shift of the mean eye position of gaze (beating field) in the direction of the fast nystagmus phases of approximately 2.6 degrees, causing asymmetrical visual cortex stimulation. The absence of a significant difference in the activation pattern of the cortical eye fields supports the view that the processing of eye movements in both horizontal directions is mediated in the same cortical ocular motor areas. Furthermore, no hemispheric dominance for OKN processing was found in right-handed volunteers. 相似文献
48.
C. K. Spies M. F. Langer F. Unglaub M. Mühldorfer-Fodor L. P. Müller C. Ahrens S. F. Schlindwein 《Der Unfallchirurg》2016,119(8):673-689
A precise medical history and specific symptom-oriented clinical tests of the wrist joint should always precede any radiological, computed tomography (CT) or magnetic resonance imaging (MRI) diagnostics. In many cases, specific clinical tests of the wrist joint allow at least a preliminary diagnosis, which can be supported by standard radiography using correct projections. A systematic approach is recommended covering the radiocarpal, midcarpal, ulnocarpal and distal radioulnar joints. Exact identification of the palpable anatomic landmarks is mandatory for correct application and interpretation of the various clinical tests. The results of the clinical tests in combination with radiological imaging can often detect precisely ruptures of distinct wrist joint ligaments and localized arthritis. 相似文献
49.
50.
Antimicrobial peptides: a potential role in ocular therapy 总被引:1,自引:0,他引:1
Yulina Aliwarga MSc MAppSc Emma BH Hume PhD Jenny Lan PhD Mark DP Willcox PhD 《Clinical & experimental ophthalmology》2001,29(3):157-160
Bacterial pathogens are often involved in contact lens‐related adverse responses. This study aimed to find antimicrobial peptides and proteins that effectively eradicate or inhibit ocular bacteria. The antimicrobials were screened against Gram‐ negative and Gram‐positive bacteria originating from ocular sources. The viability of these ocular bacteria was measured after exposure to the peptides and proteins. Two conditions were used to grow bacteria, low nutrient phosphate‐buffered saline and high nutrient tryptone soya broth. Samples were taken at different times up to 48 h. In low nutrient conditions, protamine was found to be the most effective against all strains. Melittin was very effective against all strains except Serratia and one Pseudomonas isolate which were partially affected. In high nutrient condition, only melittin was effective in killing Staphylococcus aureus. Protamine and the combination of protamine and melittin had the greatest effect in eradicating the bacteria tested in low nutrient condition. Protamine alone and its combination with melittin may have potential therapeutic agents for ocular infections in an era of emerging antibiotic resistance. 相似文献