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11.
Jens Toft Birger Hesse Alan Rabøl Steen Carstensen Samir Ali 《European journal of nuclear medicine and molecular imaging》1997,24(4):409-414
Reference data files support the evaluation of myocardial perfusion single-photon emission tomography (SPET). The aim of this study was to create a large reference data base for technetium-99m sestamibi SPET, age and gender matched to the general patient population. One hundred and twenty-eight healthy volunteers (76 males and 52 females) with a likelihood of coronary artery disease of less than 5% underwent rest and maximal exercise99mTc-sestamibi SPET with a 2-day protocol and 180° elliptical rotation. The normalized activity values of99mTc-sestamibi in the inferior wall differed significantly between men and women. Age variations were found for men in the anterior wall. Normalized activity values in all four walls were strikingly similar during rest and stress. Our results suggest that the use of reference files in99mTc-sestamibi SPET requires a gender- and, for males, possibly an age-matched reference population. Different reference files at rest and during stress might not be necessary. 相似文献
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Fattouch S Acheche H M'hirsi S Mellouli L Bejar S Marrakchi M Marzouki N 《Journal of virological methods》2005,127(2):126-132
Genetic diversity was characterized in 20 isolates of Grapevine fanleaf virus (GFLV) recovered from naturally infected grapevine plants (Vitis vinifera) in the North of Tunisia. Viral RNAs were isolated by oligoprobe capture, and a 605 bp fragment containing a part of the viral coat protein gene was amplified by RT-PCR. Sequence variation among isolates was characterized by restriction fragment length polymorphism (RFLP) analysis and confirmed by sequencing. The GFLV infections are found as a complex mixture of closely related genomes. In further studies, RFLP analyses of virus isolates using AluI showed that GFLV populations in Tunisian vineyards consist of two restrictotypes corresponding to distinct sub-populations Sp1 and Sp2. The relative field distribution of these sub-populations showed that Sp2 was more abundant. Individual genomes were recovered by cloning the RT-PCR products. The sequences were found to vary from each other by as much as 11%. Cloning from mixed infections showed that Sp2 are also predominant. 相似文献
15.
Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction 总被引:23,自引:0,他引:23 下载免费PDF全文
16.
Saeed Bohlega Asmahan Al Shubili Abdulrahman Edris Abdulrahman Alreshaid Thamer AlKhairallah M Walid AlSous Samir Farah Khaled K Abu-Amero 《BMC medical genetics》2007,8(1):67
Background
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is increasingly recognized as an inherited arterial disease leading to a step-wise decline and eventually to dementia. CADASIL is caused by mutations in NOTCH3 epidermal growth factor-like repeat that maps to chromosome 19. CADASIL cases have been identified in most countries of Western and Central Europe, the Americas, Japan, Australia, the Caribbean, South America, Tanzania, Turkey, South Africa and Southeast Asia, but not in Arabs. 相似文献17.
Ring-stage parasitized erythrocytes (RPEs) were demonstrated to interact with effector cells of the innate immune system. With receptor blockade studies and CD36-null macrophages, human and murine macrophages were shown to phagocytose RPEs through the pattern recognition receptor CD36. These in vitro data implicate scavenger receptors in the clearance of RPEs. 相似文献
18.
Philippe A. Puech Loïc Boussel Samir Belfkih Laurent Lemaitre Philippe Douek Régis Beuscart 《Journal of digital imaging》2007,20(2):122-130
DicomWorks is freeware software for reading and working on medical images [digital imaging and communication in medicine (DICOM)].
It was jointly developed by two research laboratories, with the feedback of more than 35,000 registered users throughout the
world who provided information to guide its development. We detail their occupations (50% radiologists, 20% engineers, 9%
medical physicists, 7% cardiologists, 6% neurologists, and 8% others), geographic origins, and main interests in the software.
The viewer’s interface is similar to that of a picture archiving and communication system viewing station. It provides basic
but efficient tools for opening DICOM images and reviewing and exporting them to teaching files or digital presentations.
E-mail, FTP, or DICOM protocols are supported for transmitting images through a local network or the Internet. Thanks to its
wide compatibility, a localized (15 languages) and user-friendly interface, and its opened architecture, DicomWorks helps
quick development of non proprietary, low-cost image review or teleradiology solutions in developed and emerging countries. 相似文献
19.
The significant advances in our understanding of color vision has been due to the convergence of information from behavioral
and molecular genetic analyses. The molecular biology of the visual pigments; molecular genetic basis of variation in normal
and abnormal color vision, and regulation of the genes at the LWS-MWS pigment gene locus are discussed. 相似文献
20.
Elena Formisano Andrea Pasta Anna Laura Cremonini Ilaria Di Lorenzo Samir Giuseppe Sukkar Livia Pisciotta 《Nutrients》2021,13(4)
Background: Dyslipidemia is one of the major causes of atherosclerotic cardiovascular disease (ASCVD) and a Mediterranean Diet (MD) is recommended for its prevention. The objectives of this study were to evaluate adherence to an MD at baseline and follow-up, in a cohort of dyslipidemic patients, and to evaluate how different food intakes can influence lipid profile, especially how different sources of saturated fatty acids impact lipid phenotype. Methods: A retrospective analysis was conducted on 106 dyslipidemic patients. Clinical characteristics, lipid profile, and food habits data were collected at baseline and after three months of follow-up with counseling. Adherence to an MD was evaluated with a validated food-frequency questionnaire (MEDI-LITE score). Results: The cross-sectional analysis showed that higher consumption of dairy products correlated independently with higher levels of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) and with lower triglycerides (TG) levels. Instead, lower HDL-C and TG levels and higher TC levels were independently associated with higher consumption of meat products. Adherence to an MD significantly improved after the follow-up period, from a mean value of 10 ± 3 (median 10, IQR 8–12) to 13 ± 2 (median 14, IQR 12–15), p < 0.0001. Conclusions: Dyslipidemic patients benefit from counseling for improving their adherence to an MD. The high intake of dairy products was associated with less atherogenic hyperlipidemia, which was characterized by higher levels of TC and HDL-C as compared withs the intake of an excessive amount of meat products, which was associated with higher levels of TC and TG and lower levels of HDL-C. 相似文献