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排序方式: 共有3929条查询结果,搜索用时 15 毫秒
141.
Cristián Biscayart María Eugenia Pérez Carrega Sandra Sagradini Ángela Gentile Daniel Stecher Tomás Orduna Silvia Bentancourt Salvador García Jiménez Luis Pedro Flynn Gabriel Pirán Arce María Andrea Uboldi Laura Bugna María Alejandra Morales Clara Digilio Cintia Fabbri Delia Enría Máximo Diosque Carla Vizzotti 《Vaccine》2014
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145.
Jiapiao Zhuang Gerard Tromp Helena Kuivaniemi Salvador Castells Darwin J. Prockop 《American journal of medical genetics. Part A》1996,61(2):111-116
A substitution of arginine for glycine at amino acid position 154 of the α1(I) collagen chain was found in a father and his three children. The phenotype of the patients includes manifestations of types I and III/IV osteogenesis imperfecta, but appears to be milder than that of the previously described two unrelated patients that had the identical mutation in the α1(I) collagen chain. The variability in the phenotype raises the possibility of epistatic loci or environmental effects on expression of the disorder. © 1996 Wiley-Liss, Inc. 相似文献
146.
Liliana Muschietti Virginia Martino Graciela Ferraro Jorge Coussio Laura Segura Carmen Carta Salvador Caigueral Toms Adzet 《Phytotherapy research : PTR》1996,10(1):84-86
Extracts (aqueous, methanol and dichloromethane) from Ambrosia tenuifolia, Aristolochia triangularis, Baccharis tucumanensis, Campyloneuron phyllitidis and Eupatorium christieanum were screened for antiinflammatory activity. On the croton oil induced mouse ear oedema test, the highest activities were exhibited by dichloromethane extracts assayed, especially those of Baccharis tucumanensis and Campyloneuron phyllitidis. On the carrageenan mouse paw oedema test, Baccharis tucumanensis and Campyloneuron phyllitidis showed the highest activity. 相似文献
147.
Victor Rimbau Esther Risco Salvador Canigueral Josep Iglesias 《Phytotherapy research : PTR》1996,10(5):421-423
Aqueous, ethanol and chloroform extracts from five plants were administered either topically (oedema induced by arachidonic acid in mouse ear) or i.p. (subplantar oedema induced by carrageenan in rats). Our results show that Anacyclus pyrethrum, Armeria alliacea, Asphodelus ramosus, Capparis spinosa and Rhaponticum acaule possess antiinflammatory activity, since at least one extract of each plant was active in one of the experimental models. The three extracts from Anacyclus pyrethrum showed significant activity in both experimental models, but the highest antiinflammatory activity was exhibited by the polar extracts of Armeria alliacea . The ethanol extract of the latter produced 100% inhibition of the inflammation induced by carrageenan and this inhibition was highly significant ( p <0.001) with reference to values found in both active (indomethacin 3 mg/kg) and vehicle administered control groups. 相似文献
148.
Otilia Perichart-Perera Jennifer Mier-Cabrera Claudia Montserrat Flores-Robles Nayeli Martínez-Cruz Lidia Arce-Snchez Itzel Nallely Alvarado-Maldonado Araceli Montoya-Estrada Jos Romo-Yaez Ameyalli Mariana Rodríguez-Cano Guadalupe Estrada-Gutierrez Salvador Espino y Sosa Mario Guzmn-Huerta Rodrigo Ayala-Yaez Enrique Reyes-Muoz 《Nutrients》2022,14(1)
The aim of this study was to examine the efficacy of intensive medical nutrition therapy (MNT) plus metformin in preventing gestational diabetes mellitus (GDM) among high-risk Mexican women. An open-label randomized clinical trial was conducted. Inclusion criteria were pregnant women with three or more GDM risk factors: Latino ethnic group, maternal age >35 years, body mass index >25 kg/m2, insulin resistance, and a history of previous GDM, prediabetes, a macrosomic neonate, polycystic ovarian syndrome, or a first-degree relative with type 2 diabetes. Women before 15 weeks of gestation were assigned to group 1 (n = 45): intensive MNT-plus metformin (850 mg twice/day) or group 2 (n = 45): intensive MNT without metformin. Intensive MNT included individual dietary counseling, with ≤50% of total energy from high carbohydrates. The primary outcome was the GDM incidence according to the International Association of Diabetes Pregnancy Study Groups criteria. There were no significant differences in baseline characteristics and adverse perinatal outcomes between the groups. The GDM incidence was n = 11 (24.4%) in the MNT plus metformin group versus n = 7 (15.5%) in the MNT without metformin group: p = 0.42 (RR: 1.57 [95% CI: 0.67–3.68]). There is no benefit in adding metformin to intensive MNT to prevent GDM among high-risk Mexican women. Clinical trials registration: . NCT01675310相似文献
149.
Irene Lorite-Fuentes Trinidad Montero-Vilchez Salvador Arias-Santiago Alejandro Molina-Leyva 《Nutrients》2022,14(3)
There is scarce scientific information regarding the potential benefits of healthy lifestyles in patients with hidradenitis suppurativa (HS). The objective of this study is to explore the potential association between the adherence to a Mediterranean diet (MD), physical activity and HS severity. A cross-sectional study that included patients with HS was conducted. Disease severity was evaluated by the International Hidradenitis Suppurativa Severity Score System (IHS4) and self-reported disease activity using a Numeric Rating Scale (NRS, 0–10). The adherence to a MD was assessed by the PREvención con DIeta MEDiterránea (PREDIMED) questionnaire and the level of physical activity by the International Physical Activity questionnaire. A total of 221 patients with HS were included in our study. The adherence to a MD was average for a Spanish population. A higher adherence to a MD was associated with lower disease activity, lower self-reported Hurley and lower IHS4. The use of extra virgin olive oil as the main culinary lipid was the dietary habit that implied a lower degree of disease activity (p < 0.05). Regarding physical activity, both the self-reported severity and IHS4 presented an inverse association with the intensity of physical activity. The adherence to a MD and the intensity of physical activity were positively associated. The Mediterranean dietary pattern may have an impact on HS. Greater adherence to a MD is related to lower HS severity and more physical activity also correlates to lower disease severity. The MD could be an appropriate dietary pattern for patients with HS due to its anti-inflammatory properties, and combining this with increased levels of physical activity could have additional benefits. 相似文献
150.
Yan Sun PhD Sameer C. Dhamne MS Alejandro Carretero-Guillén PhD Ricardo Salvador PhD Marti C. Goldenberg BS Brianna R. Godlewski BS Alvaro Pascual-Leone MD PhD Joseph R. Madsen MD Scellig S. D. Stone MD PhD Giulio Ruffini PhD Javier Márquez-Ruiz PhD Alexander Rotenberg MD PhD 《Annals of neurology》2020,88(3):489-502