全文获取类型
收费全文 | 2354803篇 |
免费 | 169811篇 |
国内免费 | 4724篇 |
专业分类
耳鼻咽喉 | 31736篇 |
儿科学 | 73493篇 |
妇产科学 | 63264篇 |
基础医学 | 334957篇 |
口腔科学 | 70207篇 |
临床医学 | 210840篇 |
内科学 | 457945篇 |
皮肤病学 | 52195篇 |
神经病学 | 183125篇 |
特种医学 | 89458篇 |
外国民族医学 | 319篇 |
外科学 | 362253篇 |
综合类 | 52744篇 |
现状与发展 | 4篇 |
一般理论 | 751篇 |
预防医学 | 171384篇 |
眼科学 | 56098篇 |
药学 | 175545篇 |
10篇 | |
中国医学 | 5906篇 |
肿瘤学 | 137104篇 |
出版年
2019年 | 17778篇 |
2018年 | 26016篇 |
2017年 | 19926篇 |
2016年 | 22026篇 |
2015年 | 25107篇 |
2014年 | 34565篇 |
2013年 | 50517篇 |
2012年 | 69789篇 |
2011年 | 73403篇 |
2010年 | 43486篇 |
2009年 | 40935篇 |
2008年 | 69133篇 |
2007年 | 73236篇 |
2006年 | 74134篇 |
2005年 | 70802篇 |
2004年 | 68473篇 |
2003年 | 65203篇 |
2002年 | 63112篇 |
2001年 | 125534篇 |
2000年 | 128678篇 |
1999年 | 106680篇 |
1998年 | 27322篇 |
1997年 | 23906篇 |
1996年 | 23985篇 |
1995年 | 22924篇 |
1994年 | 21034篇 |
1993年 | 19469篇 |
1992年 | 80982篇 |
1991年 | 77984篇 |
1990年 | 75138篇 |
1989年 | 72558篇 |
1988年 | 66028篇 |
1987年 | 64421篇 |
1986年 | 60641篇 |
1985年 | 57627篇 |
1984年 | 42072篇 |
1983年 | 35842篇 |
1982年 | 19741篇 |
1979年 | 37363篇 |
1978年 | 25642篇 |
1977年 | 21862篇 |
1976年 | 20000篇 |
1975年 | 21345篇 |
1974年 | 25868篇 |
1973年 | 24788篇 |
1972年 | 23160篇 |
1971年 | 21588篇 |
1970年 | 20264篇 |
1969年 | 18945篇 |
1968年 | 17555篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
71.
P E Santos E Piontelli Y R Shea M L Galluzzo S M Holland M E Zelazko S D Rosenzweig 《Medical mycology》2006,44(8):749-753
Infections due to Penicillium species other than P.marneffei are rare. We identified a boy with X-linked chronic granulomatous disease (X-CGD) with a pulmonary nodule and adjacent rib osteomyelitis caused by Penicillium piceum. The only sign of infection was an elevated sedimentation rate. P. piceum was isolated by fine needle aspirate and from excised infected tissues. Surgical removal and one year of voriconazole treatment were very well tolerated and led to complete recovery. Microbiological, microscopic and molecular studies support the fungal diagnosis. P. piceum should be considered as a relevant pathogen in immunocompromised patients. 相似文献
72.
73.
74.
75.
76.
A. Cagnin M. Kassiou S. R. Meikle R. B. Banati 《Acta neurologica Scandinavica》2006,114(S185):107-114
77.
H J Kim C H Kang Y T Kim S-W Sung J H Kim S M Lee C-G Yoo C-T Lee Y W Kim S K Han Y-S Shim J-J Yim 《The European respiratory journal》2006,28(3):576-580
Although surgical lung resection could improve prognosis in some patients with multidrug-resistant tuberculosis (MDR-TB), there are no reports on the optimal candidates for this surgery. The aim of the present study was to elucidate the prognostic factors for surgery in patients with MDR-TB. Patients who underwent lung resection for the treatment of MDR-TB between March 1993 and December 2004 were included in the present study. Treatment failure was defined as greater than or equal to two of the five cultures recorded in the final 12 months of treatment being positive, any one of the final three cultures being positive, or the patient having died during treatment. The variables that affected treatment outcomes were identified through univariate and multivariate logistic regression analysis. In total, 79 patients with MDR-TB were included in the present study. The treatment outcomes of 22 (27.8%) patients were classified as failure. A body mass index <18.5 kg x m(-2), primary resistance, resistance to ofloxacin and the presence of a cavitary lesion beyond the range of the surgical resection were associated with treatment failure. Low body mass index, primary resistance, resistance to ofloxacin and cavitary lesions beyond the range of resection are possible poor prognostic factors for surgical lung resection in multidrug-resistant tuberculosis patients. 相似文献
78.
79.
Katharine R. Owen Mollie Donohoe Sian Ellard Andrew T. Hattersley 《Diabetic medicine》2003,20(10):823-827
Background Familial partial lipodystrophy (FPLD) is a monogenic form of diabetes characterised by a dominantly inherited disorder of adipose tissue associated with the loss of subcutaneous fat from the limbs and trunk, with excess fat deposited around the face and neck. The lipodystrophy causes severe insulin resistance, resulting in acanthosis nigricans, diabetes, dyslipidaemia, and increased risk of cardiovascular disease. Preliminary results from animals and man suggest that increasing subcutaneous fat by treatment with thiazolidinediones should improve insulin resistance and the associated features of this syndrome. Case report We report a 24-year-old patient with FPLD caused by a mutation in the LMNA gene (R482W) treated with 12 months of rosiglitazone. Subcutaneous fat increased following rosiglitazone treatment as demonstrated by a 29% generalised increase in skin-fold thickness. Leptin levels increased from 5.8 to 11.2 ng/ml. Compared with treatment on Metformin, there was an increase in insulin sensitivity (HOMA S% 17.2–31.6) but no change in glycaemic control. The lipid profile worsened during the follow-up period. Conclusion This initial case suggests that, for modification of cardiovascular risk factors, there are no clear advantages in treating patients with FPLD with rosiglitazone despite increases in subcutaneous adipose tissue. Larger series will be needed to identify moderate beneficial effects and treatment may be more effective in patients with generalised forms of lipodystrophy. 相似文献
80.