全文获取类型
收费全文 | 803篇 |
免费 | 26篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 12篇 |
妇产科学 | 33篇 |
基础医学 | 122篇 |
口腔科学 | 24篇 |
临床医学 | 62篇 |
内科学 | 206篇 |
皮肤病学 | 9篇 |
神经病学 | 78篇 |
特种医学 | 10篇 |
外科学 | 49篇 |
综合类 | 17篇 |
预防医学 | 83篇 |
眼科学 | 11篇 |
药学 | 65篇 |
中国医学 | 23篇 |
肿瘤学 | 22篇 |
出版年
2023年 | 3篇 |
2022年 | 16篇 |
2021年 | 30篇 |
2020年 | 11篇 |
2019年 | 33篇 |
2018年 | 17篇 |
2017年 | 10篇 |
2016年 | 15篇 |
2015年 | 15篇 |
2014年 | 26篇 |
2013年 | 45篇 |
2012年 | 71篇 |
2011年 | 74篇 |
2010年 | 43篇 |
2009年 | 40篇 |
2008年 | 53篇 |
2007年 | 49篇 |
2006年 | 54篇 |
2005年 | 60篇 |
2004年 | 49篇 |
2003年 | 42篇 |
2002年 | 27篇 |
2000年 | 1篇 |
1999年 | 5篇 |
1998年 | 1篇 |
1997年 | 4篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1994年 | 3篇 |
1993年 | 3篇 |
1992年 | 3篇 |
1990年 | 2篇 |
1989年 | 3篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1986年 | 2篇 |
1985年 | 2篇 |
1983年 | 3篇 |
1982年 | 2篇 |
1981年 | 3篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1976年 | 1篇 |
1974年 | 1篇 |
1967年 | 1篇 |
排序方式: 共有832条查询结果,搜索用时 3 毫秒
71.
72.
Jose Perea Edurne Alvaro Yolanda Rodríguez Cristina Gravalos Eva Sánchez-Tomé Barbara Rivera Francisco Colina Pablo Carbonell Rogelio González-Sarmiento Manuel Hidalgo Miguel Urioste 《World journal of gastroenterology : WJG》2010,16(29):3697-3703
AIM:To characterize clinicopathological and familial features of early-onset colorectal cancer(CRC) and compare features of tumors with and without microsatellite instability(MSI).METHODS:Forty-five patients with CRC aged 45 or younger were included in the study.Clinical information,a three-generation family history,and tumor samples were obtained.MSI status was analyzed and mismatch repair genes were examined in the MSI families.Tumors were included in a tissue microarray and an immunohistochemical study w... 相似文献
73.
Tropical alphaviruses have special tropism for bone and joint tissue. Patients can develop chronic rheumatic disorders similar to rheumatoid arthritis and ankylosing spondylitis. The prototype is Chikungunya virus, although other lesser known viruses in our environment such as Sindbis, Ross River, Mayaro, O’nyong nyong and Barmah Forest viruses have the potential to be sped through vectors and cause chronic rheumatic disease.International population movements have increased the numbers of patients diagnosed with these tropical viruses in areas in which they are not endemic. Since they can leave persistent symptoms and affect the quality of life of the patients, it is important that we be aware of them. Changes in ecosystems have favored the expansion of competent mosquitoes, making fears of local transmission in southern Europe a reality.The objective of this review is to provide a clinical approach to the different arthritogenic tropical alphaviruses, especially those in which chronic rheumatic disease is more frequent. 相似文献
74.
Rosario Fernández-Plata Rogelio Pérez-Padilla Rodrigo Del Río-Hidalgo Cecilia García-Sancho Laura Gochicoa-Rangel Christian Rodríguez-Hernández Luis Torre-Bouscoulet David Martínez-Briseño 《Archivos de bronconeumología》2019,55(10):513-518
IntroductionPeople with Down syndrome (DS) have high respiratory morbidity, evaluating their respiratory health with standardized, objective tests is desirable. Thus, the objective of this study was to evaluate the technical quality of Pulmonary Function Tests (PFTs) to determine which ones are most suitable for this population.MethodsParticipants included children, teenagers and adults with DS, 5 years of age or older (n = 302). The technical quality of the impulse oscillometry system (IOS), forced spirometry, lung-diffusing capacity for carbon monoxide (DLCO), and 6-min walk test (6MWT) were analyzed by age group. Capnography and pulse oximetry were included in the study. Technical quality was determined on the basis of current international PFTs standards.ResultsFifty-one percent of participants were males. A total of 184 participants (71%) who completed the IOS fulfilled the quality criteria, while 210 (70%) completed the 6MWT. Performance on forced spirometry and DLCO was poor. All pulse oximetries and 96% percent heart rates obtained had good quality, but exhaled carbon dioxide (PetCO2) and respiratory rate (RR) showed deficient repeatability.ConclusionsIOS appears to be the most reliable instrument for evaluating lung mechanics in individuals with DS. 相似文献
75.
76.
Comerford KB Almario RU Kim K Karakas SE 《Metabolism: clinical and experimental》2012,61(9):1256-1260
Insulin resistance is common in women with polycystic ovary syndrome (PCOS). Muscle is the major tissue utilizing glucose while excess adipose tissue relates to insulin resistance. Thus, body composition is likely to be an important regulator of insulin sensitivity. Thirty-nine PCOS patients (age: 29.9 ± 1.0 years; BMI: 33.8 ± 1.2 kg/m2) participated in a cross sectional study. Body composition was measured by dual energy x-ray absorptiometry (DEXA). Insulin resistance and secretion were assessed using oral glucose tolerance test (OGTT) and frequently sampled intravenous glucose tolerance test (FS-IVGTT). In contrast with the conventional expectations, lean mass correlated directly (P < .05) with the insulin resistance measure HOMA (r = 0.440); and inversely with the insulin sensitivity index QUICKI (r = ?0.522) independent of fat mass. In 11 pairs of subjects matched for fat mass (35.6 ± 2.2 and 35.6 ± 2.4 kg) but with discordant lean mass (52.8 ± 1.8 vs 44.4 ± 1.6 kg), those with higher lean mass had a higher glucose response during OGTT (AUCGlucose; P = .034). In contrast, 17 pairs matched for lean mass (48.7 ± 1.7 and 48.9 ± 1.6 kg) but discordant for fat mass (43.3 ± 2.6 vs 30.3 ± 8.9 kg) showed no differences in insulin resistance parameters. These novel findings indicate that lean mass relates directly to insulin resistance in PCOS. 相似文献
77.
Acute kidney injury (AKI) is an ominous event in the natural history of cirrhosis. The differential diagnosis of this entity is hampered by the absence of specific biomarkers of tubular damage in cirrhosis. 相似文献
78.
Fernandez Maritza Murillo Javier Ríos-Vásquez Luz Amalia Ocampo-Cardona Rogelio Cedeño David L. Jones Marjorie A. Velez Iván D. Robledo Sara M. 《Parasitology research》2018,117(1):273-286
Parasitology Research - The physicochemical properties of four N-halomethylated and one non-halomethylated ammonium salts, with proven in vitro antileishmanial activity, were determined according... 相似文献
79.
Armendariz-Borunda J Lyra-Gonzalez I Medina-Preciado D Gonzalez-García I Martinez-Fong D Miranda RA Magaña-Castro R Peña-Santoyo P Garcia-Rocha S Bautista CA Godoy J Flores-Montana J Floresvillar-Mosqueda J Armendariz-Vazquez O Lucano-Landeros MS Vazquez-Del Mercado M Sanchez-Parada MG 《Annals of plastic surgery》2012,68(1):22-28
80.