全文获取类型
收费全文 | 8718篇 |
免费 | 495篇 |
国内免费 | 77篇 |
专业分类
耳鼻咽喉 | 62篇 |
儿科学 | 258篇 |
妇产科学 | 182篇 |
基础医学 | 961篇 |
口腔科学 | 243篇 |
临床医学 | 640篇 |
内科学 | 2285篇 |
皮肤病学 | 189篇 |
神经病学 | 618篇 |
特种医学 | 441篇 |
外科学 | 1365篇 |
综合类 | 26篇 |
一般理论 | 1篇 |
预防医学 | 386篇 |
眼科学 | 70篇 |
药学 | 507篇 |
中国医学 | 16篇 |
肿瘤学 | 1040篇 |
出版年
2024年 | 13篇 |
2023年 | 117篇 |
2022年 | 179篇 |
2021年 | 369篇 |
2020年 | 212篇 |
2019年 | 300篇 |
2018年 | 353篇 |
2017年 | 240篇 |
2016年 | 280篇 |
2015年 | 294篇 |
2014年 | 426篇 |
2013年 | 475篇 |
2012年 | 700篇 |
2011年 | 707篇 |
2010年 | 390篇 |
2009年 | 333篇 |
2008年 | 560篇 |
2007年 | 537篇 |
2006年 | 486篇 |
2005年 | 536篇 |
2004年 | 454篇 |
2003年 | 417篇 |
2002年 | 345篇 |
2001年 | 43篇 |
2000年 | 34篇 |
1999年 | 44篇 |
1998年 | 75篇 |
1997年 | 58篇 |
1996年 | 50篇 |
1995年 | 39篇 |
1994年 | 35篇 |
1993年 | 28篇 |
1992年 | 14篇 |
1991年 | 15篇 |
1990年 | 16篇 |
1989年 | 15篇 |
1988年 | 15篇 |
1987年 | 8篇 |
1986年 | 16篇 |
1985年 | 6篇 |
1984年 | 7篇 |
1983年 | 7篇 |
1982年 | 7篇 |
1981年 | 6篇 |
1980年 | 7篇 |
1977年 | 3篇 |
1975年 | 2篇 |
1971年 | 2篇 |
1965年 | 2篇 |
1904年 | 2篇 |
排序方式: 共有9290条查询结果,搜索用时 15 毫秒
31.
32.
33.
Ester Illiano Francesco Trama Vito Mancini Antonio Ruffo Giuseppe Romeo Filippo Riccardo Consuelo Fabi Giuseppe Carrieri Felice Crocetto Fabrizio Iacono Elisabetta Costantini 《Translational andrology and urology》2021,10(2):555
BackgroundPeyonie’s disease (PD) mostly affects males in the fifth decade of life, with a prevalence in the general population ranging between 0.5% and 20.3%. The pathology of PD is characterized by fibrosis of the tunic albuginea of the cavernous bodies of the penis, with the presence of pain in the erection and penile deformity. This is associated with decreased sexual function for both participants. The objective of the study was to investigate the influence of PD pathology on both male patients’ and their female partners’ sexual spheres, and analyze changes in sexual function and perception following penile correction surgery.MethodsProspective study, we included male patients with PD and their female partner sexually active. Patients underwent corporoplasty with multiple plications. The male and female sexuality was evaluated before surgery and three months after male treatment by the Female sexual Function Index (FSFI); International Index of Erectile Function (IIEF); Visual Analogical Scale (VAS).ResultsFrom January 2018 to November 2019 we included 35 couple. The female subjects before partner’s surgery presented dyspareunia, loss of sexual desire, inability to achieve orgasm, and sexual dissatisfaction. At three months after surgical treatment there was an improvement of sexual function in both male patients and female partners (desire P<0.0001, arousal P<0.0001, lubrification P<0.0001, orgasm P<0.0001, satisfaction P<0.0001, pain P<0.0001). As regarding male patients the pain decreased significantly (VAS score from 6 to 2.5), while there was no statistically significant improvement in erectile function (P=0.05).ConclusionsOur findings suggest that a viable approach to treatment of PD patients that involves their partners could lead to better functional and psychological results. 相似文献
34.
Riccardo Memeo Maria Conticchio Emmanuel Deshayes Silvio Nadalin Astrid Herrero Boris Guiu Fabrizio Panaro 《肝胆外科与营养》2021,10(3):350
Liver resection still represent the treatment of choice for liver malignancies, but in some cases inadequate future remnant liver (FRL) can lead to post hepatectomy liver failure (PHLF) that still represents the most common cause of death after hepatectomy. Several strategies in recent era have been developed in order to generate a compensatory hypertrophy of the FRL, reducing the risk of post hepatectomy liver failure. Portal vein embolization, portal vein ligation, and ALLPS are the most popular techniques historically adopted up to now. The liver venous deprivation and the radio-embolization are the most recent promising techniques. Despite even more precise tools to calculate the relationship among volume and function, such as scintigraphy with 99mTc-mebrofenin (HBS), no consensus is still available to define which of the above mentioned augmentation strategy is more adequate in terms of kind of surgery, complexity of the pathology and quality of liver parenchyma. The aim of this article is to analyse these different strategies to achieve sufficient FRL. 相似文献
35.
Pierangelo Geppetti Riccardo Patacchini Roberto Cecconi Manuela Tramontana Stefania Meini Andrea Romania Marco Nardi Carlo Alberto Maggi 《Naunyn-Schmiedeberg's archives of pharmacology》1990,341(4):301-307
Summary Capsaicin-sensitive sensory neurons of the rabbit iris, by releasing tachykinins, exert a major role in the control of pupil motility in response to various noxious stimuli. However, the contribution of sensory innervation to the regulation of iris smooth muscle tone in other mammals species is not known. We have studied the effects produced by electrical field stimulation, capsaicin, substance P, neurokinin A, calcitonin gene-related peptide (CGRP), and bradykinin in the isolated iris sphincter muscle of the pig.Capsaicin (10 M): a) contracted the isolated sphincter muscle and; b) released immunoreactivity for substance P (SP-LI) and CGRP (CGRP-LI) from this preparation. These two effects were no longer observed at the second exposure to the drug. Electrical field stimulation (10 Hz, 60 V, 0.5 ms for 5 s) produced a biphasic contractile response. The rapid component was inhibited by atropine (1 M), while the delayed response was blocked by previous exposure to capsaicin (10 M).Substance P and neurokinin A consistently produced contraction of the pig iris sphincter muscle, substance P being more potent than neurokinin A. CGRP induced a contractile response in more than 50% of the preparations. The tachykinin antagonist [D-Argl, D-Trp7,9, Leu11-substance P (3 M) blocked: a) the effect of substance P (1 nM); b) the delayed response to electrical field stimulation and; c) reduced by more than 50% response to capsaicin. Bradykinin (10 M) failed to release either SP-LI or CGRP-LI. The contractile response evoked by bradykinin was unaffected by in vitro pretreatment with capsaicin (10 M).The existence in the pig iris of capsaicin-sensitive sensory fibres releasing neuropeptides and thus regulating sphincter muscle tone is proposed.
Send offprint requests to Dr. P. Geppetti at the above address 相似文献
36.
Riccardo Patacchini Carlo Alberto Maggi Alberto Meli 《Naunyn-Schmiedeberg's archives of pharmacology》1990,342(1):72-77
Summary 1. The effects of some naturally occurring pungent substances, piperine, mustard oil, eugenol and curcumin, were compared to those of capsaicin in the rat isolated urinary bladder. 2. All test compounds dose-dependently contracted the rat bladder and produced desensitization toward capsaicin (1 mol/l). Development of cross-tachyphylaxis among the natural pungent substances on one hand and capsaicin on the other, suggested a common site of action on visceral primary afferents. 3. Contractile responses to piperine, mustard oil and eugenol were partially tetrodotoxin and ruthenium red-sensitive, suggesting that activation of sensory terminals by these agents takes place indirectly, as well as by a direct action on sensory receptors. 4. The presence of the secondary acylamide linkage (present in the backbone of capsaicin, but not in that of test compounds) does not appear to be essential to produce desensitization of sensory nerve terminals.
Send offprint requests to R. Patacchini at the above address 相似文献
37.
Chlorhexidine susceptibility and Eagle effect in planktonic cells and biofilm of nosocomial isolates
Marchi Ana Paula Farrel Côrtes Marina Vásconez Noguera Saidy Rossi Flavia Levin Anna Sara Figueiredo Costa Silvia Perdigão Neto Lauro Vieira 《European journal of clinical microbiology & infectious diseases》2023,42(6):787-792
European Journal of Clinical Microbiology & Infectious Diseases - The aim of this study is to evaluate the chlorhexidine gluconate (CHG) susceptibility in both planktonic cells and biofilm of... 相似文献
38.
39.
Salvatore Restivo MD Riccardo Speciale MD Rosalia Gargano MD Riccardo Di Leo MD Francesco Farinella MD Salvatore Gallina MD 《Operative Techniques in Otolaryngology》2003,14(2):153-156
During the last 20 years, various conservative surgical techniques have been proposed to treat larynx cancer. On the basis of our various experiences and of the ultrastructural data on the tissues treated with radiowaves, we decided to also use radiosurgery in operations under direct microlaryngoscopy. We select 18 patients suffering from epidermoid carcinoma. These patients had been referred to our ENT clinic at the Polichnico of Palermo between 1999 and 2001. The authors describe the surgical procedures used and emphasize the advantages of radiosurgery in the treatment of larynx cancer. 相似文献
40.