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E. Hosseinpour A. Shahverdi K. Parivar M. A. Sedighi Gilani M. H. Nasr‐Esfahani R. Salman Yazdi M. Sharbatoghli M. Tavalaee M. Chehrazi 《Andrologia》2014,46(4):423-429
Assessment of sperm ubiquitination and DNA fragmentation as sperm functional markers are proposed to complement routine semen analysis. This study focuses on the evaluation of these markers in infertile men with varicocele or exposed to occupational background. The results were compared with normozoospermic men. Semen parameters in both groups were lower than those in the control group. Ubiquitination median, as a marker for functionality of the ubiquitin–proteasome system, was also lower in both groups. The ubiquitination median showed a significant positive correlation with motility in both groups, while it showed only a negative correlation with sperm morphology in the varicocele group. DNA fragmentation showed a significant correlation with semen parameters, in total varicocele and also total exposure groups. In conclusion, significant difference of sperm ubiquitination between normal and study groups further validates that sperm ubiquitination as a potential molecular marker for sperm evaluation in addition to routine semen analysis in clinical laboratories. 相似文献
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Vahid Reza Dabbagh Kakhki Reza Bagheri Shahrzad Tehranian Pardis Shojaei Hassan Gholami Ramin Sadeghi David N. Krag 《Surgery today》2014,44(4):607-619
The use of sentinel node surgery for esophageal carcinoma is still under investigation. We evaluated the data available in the literature on this topic, and herein present the results in a systematic review format. PUBMED, SCOPUS, the ISI web of knowledge and the information from the annual meetings of the Japan Esophageal Society were searched using the search terms: “(esophagus OR esophageal) AND sentinel”. The outcomes of interest were the detection rate and sensitivity. Overall, 18 studies were included. The pooled detection rate was 89.2 % [82.6–93.5]. Patients with T1 and two tumors had a 17 % higher detection rate compared to those with T3 and four tumors. The pooled sensitivity was 84 % [78–88 %]. The sensitivity was higher for adenocarcinoma compared to squamous cell carcinoma (SCC) (91 vs. 81 %). In the SCC patients, there was a trend toward decreased sensitivity associated with an increasing tumor depth (T1:88 %, T2:76 %, T3:50 %). Our analysis indicated that sentinel node biopsy is useful in adenocarcinoma patients. For SCC patients, including only cN0 patients (preferably T1 and 2) would increase the detection rate and sensitivity. Due to the limited number of high-quality studies, drawing any more definite conclusions is impossible. Large cohort studies with a standardized and consistent design will be needed in the future. 相似文献
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Seyedeh-Nafiseh Hassani Mehdi Totonchi Ali Sharifi-Zarchi Sepideh Mollamohammadi Mohammad Pakzad Sharif Moradi Azam Samadian Najmehsadat Masoudi Shahab Mirshahvaladi Ali Farrokhi Boris Greber Marcos J. Araúzo-Bravo Davood Sabour Mehdi Sadeghi Ghasem Hosseini Salekdeh Hamid Gourabi Hans R. Schöler Hossein Baharvand 《Stem cell reviews》2014,10(1):16-30
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Improvement in perioperative care in pediatric cardiac surgery by shifting the primary focus of treatment from cardiac output to perfusion pressure: Are beta stimulants still needed? 下载免费PDF全文
Amir‐Reza Hosseinpour MD FRCS‐CTh Mathieu van Steenberghe MD MSc Marc‐André Bernath MD Stefano Di Bernardo MD Marie‐Hélène Pérez MD David Longchamp MD Mirko Dolci MD Yann Boegli MD Nicole Sekarski MD Javier Orrit MD Michel Hurni MD René Prêtre MD Jacques Cotting MD 《Congenital heart disease》2017,12(5):570-577
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Prognostic value of positive T wave in lead aVR in patients with non‐ST segment myocardial infarction 下载免费PDF全文
Ahmad Separham MD Bahram Sohrabi MD Arezou Tajlil MD Leili Pourafkari MD FACC Robabeh Sadeghi MD Samad Ghaffari MD Nader D. Nader MD PhD FACC FCCP 《Annals of noninvasive electrocardiology》2018,23(5)