全文获取类型
收费全文 | 3512篇 |
免费 | 211篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 37篇 |
儿科学 | 77篇 |
妇产科学 | 170篇 |
基础医学 | 451篇 |
口腔科学 | 114篇 |
临床医学 | 266篇 |
内科学 | 813篇 |
皮肤病学 | 52篇 |
神经病学 | 165篇 |
特种医学 | 99篇 |
外国民族医学 | 1篇 |
外科学 | 576篇 |
综合类 | 74篇 |
预防医学 | 266篇 |
眼科学 | 185篇 |
药学 | 240篇 |
中国医学 | 11篇 |
肿瘤学 | 150篇 |
出版年
2023年 | 23篇 |
2022年 | 69篇 |
2021年 | 160篇 |
2020年 | 67篇 |
2019年 | 106篇 |
2018年 | 118篇 |
2017年 | 99篇 |
2016年 | 93篇 |
2015年 | 95篇 |
2014年 | 160篇 |
2013年 | 181篇 |
2012年 | 223篇 |
2011年 | 252篇 |
2010年 | 140篇 |
2009年 | 132篇 |
2008年 | 181篇 |
2007年 | 172篇 |
2006年 | 157篇 |
2005年 | 166篇 |
2004年 | 138篇 |
2003年 | 116篇 |
2002年 | 97篇 |
2001年 | 65篇 |
2000年 | 68篇 |
1999年 | 55篇 |
1998年 | 21篇 |
1997年 | 16篇 |
1996年 | 21篇 |
1995年 | 15篇 |
1994年 | 17篇 |
1993年 | 14篇 |
1992年 | 54篇 |
1991年 | 50篇 |
1990年 | 47篇 |
1989年 | 49篇 |
1988年 | 28篇 |
1987年 | 29篇 |
1986年 | 33篇 |
1985年 | 30篇 |
1984年 | 24篇 |
1983年 | 14篇 |
1982年 | 12篇 |
1981年 | 9篇 |
1979年 | 20篇 |
1978年 | 11篇 |
1976年 | 10篇 |
1974年 | 10篇 |
1973年 | 11篇 |
1971年 | 10篇 |
1970年 | 9篇 |
排序方式: 共有3747条查询结果,搜索用时 46 毫秒
61.
Abdel Raouf Abou El Azm Lobna Abou-Ali Abdel Rahman Kobtan Nagwa Mansour Salwa Tawfik 《Archives of virology》2013,158(3):543-547
Hepatitis C and brucellosis are infectious diseases that occur worldwide, and both are endemic in Egypt. Co-infection with both agents is possible, and this can involve the liver in various ways. In this study, we investigated serum tissue inhibitor metalloproteinase-1 (TIMP-1), viral load, and liver functions in patients co-infected with hepatitis C virus (HCV) before and after brucellosis treatment. Over 3 years, 241 consecutive HCV patients (before interferon therapy was received) with recurrent fever who had occupational contact with animals were tested for brucellosis co-infection by a standard tube agglutination test. In patients with dual infection, viraemia (RT-PCR), TIMP-1 measured by ELISA, and liver functions were assessed and re-evaluated 2 months after brucellosis treatment. The number of patients with HCV/brucellosis co-infection was 32 out of 241 (13.3%). TIMP-1, viraemia, AST, ALT and bilirubin showed significant decrease (improvement) after brucellosis treatment (p < 0.001) but an insignificant difference (p > 0.05) with regard to serum albumin and prothrombin concentration. The study revealed that brucellosis is an important infection in HCV-infected patients and can aggravate the course of disease, suggesting that early treatment and prevention are important. 相似文献
62.
63.
Shahrokh Rahmani Amin Jarrahi Mansour Alizadeh 《Journal of medical engineering & technology》2017,41(8):630-643
One of the important parts of the cardiac system is aorta which is the fundamental channel and supply of oxygenated blood in the body. Diseases of the aorta represent critical cardiovascular bleakness and mortality around the world. This study aims at investigation of hemodynamic parameters in a two-dimensional axisymmetric model of three-layer grafted aorta using fluid–structure interaction (FSI). It assumes that a damaged part of aorta, which may happen as a result of some diseases like aneurysm, dissection and post-stenotic dilatation, is replaced with a biomaterial graft. Four types of grafts materials so-called Polyurethane, Silicone rubber, Polytetrafluoroethylene (PTFE) and Dacron are considered in the present study. The assumption of linear elastic and isotropic material is set for the both aorta's wall and aforementioned grafts. Blood is considered as an incompressible and Newtonian fluid. The results indicate higher displacement in Polyurethane and silicone rubber in comparison with other two. Furthermore, results reveal that blood flow velocity has slightly higher values in PTFE and Dacron grafted models compared to Polyurethane and Silicone rubber ones. Even though there are some differences in hemodynamic patterns in these grafted models, they are not considerable as much as von Mises stresses across the graft-aorta intersections are. This study shows that the types of material grafts play an important role in the amount of stresses particularly at intersections of aorta and graft. 相似文献
64.
65.
Spontaneous coronary artery dissection is a rare cause of myocardial ischemia. Coronary artery pseudoaneurysm may occur after percutaneous coronary interventions and rarely spontaneously. We present a patient who had spontaneous coronary artery dissection with formation of a pseudoaneurysm diagnosed by intravascular ultrasound. 相似文献
66.
67.
Stephan B Danik Moussa Mansour Jagmeet Singh Vivek Y Reddy Patrick T Ellinor David Milan E Kevin Heist Andre d'Avila Jeremy N Ruskin Theofanie Mela 《Heart rhythm》2007,4(4):439-442
BACKGROUND: The rapid evolution of implantable cardioverter-defibrillator (ICD) leads has resulted in thinner active fixation leads. While these advances have made the leads more versatile, new configurations may be associated with unforeseen complications. OBJECTIVE: The purpose of this study was to determine the incidence of perforation and dislodgement of defibrillator leads in a single center in the year 2005. METHODS: All patients who underwent percutaneous ICD implantation at the Massachusetts General Hospital using an endocardial right ventricular lead were included in this study. The specific leads analyzed were the Riata (1580/1581 and 1590/1591, St. Jude Medical, St Paul, Minnesota, USA;) and Sprint Fidelis (6949-65, Medtronic, Minneapolis, Minnesota, USA.). Information was collected retrospectively. RESULTS: A total of 130 Riata leads and 111 Sprint Fidelis leads were implanted at the Massachusetts General Hospital during this time period. A total of five lead perforations occurred in patients implanted with the Riata lead as compared with none with the Sprint Fidelis lead (3.8% vs. 0%, respectively; P <.05). Two of the five patients with perforation required pericardiocentesis for tamponade. Clinical symptoms of perforation developed 1-10 days after implant. Moreover, there were five additional lead revisions in the Riata group, which were likely due to dislodgement and/or microperforation, as compared with none in the Sprint Fidelis group (7.7% vs. 0%, respectively; P <.005). CONCLUSIONS: In 2005, at one institution, there were significantly more cardiac perforations and lead revisions with the Riata lead as compared with the Sprint Fidelis right ventricular defibrillator lead. Further data are required to determine whether certain lead characteristics are responsible for this observation. 相似文献
68.
69.
E. Kevin Heist Jianping Chevalier Godtfred Holmvang Jagmeet P. Singh Patrick T. Ellinor David J. Milan Andre D’Avila Theofanie Mela Jeremy N. Ruskin Moussa Mansour 《Journal of interventional cardiac electrophysiology》2006,17(1):21-27
Objective Integration of 3-D electroanatomic mapping with Computed Tomographic (CT) and Magnetic Resonance (MR) imaging is gaining acceptance
to facilitate catheter ablation of atrial fibrillation. This is critically dependent on accurate integration of electroanatomic
maps with CT or MR images. We sought to examine the effect of patient- and technique-related factors on integration accuracy
of electroanatomic mapping with CT and MR imaging of the left atrium.
Materials and methods Sixty-one patients undergoing catheter-based atrial fibrillation (AF) ablation procedures were included. All patients underwent
cardiac CT (n = 11) or MR (n = 50) imaging, and image integration with real-time electroanatomic mapping of the aorta and left atrium (LA). CARTO-Merge
software (Biosense-Webster) was used to calculate the overall average accuracy of integration of electroanatomic points with
the CT and MR-derived reconstructions of the LA and aorta.
Results There was a significant correlation between LA size assessed by electroanatomic mapping (112 ± 31 ml) and average integration
error (1.9 ± 0.6 mm) (r = 0.46, p = 0.0003). There was also greater integration error for patients with LA volume ≥ 110 ml (n = 31) versus < 110 ml (n = 30) (p = 0.004). In contrast, there was no significant association between average integration error and paroxysmal versus persistent
AF, left ventricular ejection fraction, days from imaging to electroanatomic mapping, or images derived from CT versus MR.
Conclusions Patients with larger LA volume may be prone to greater error during integration of electroanatomic mapping with CT and MR
imaging. Strategies to reduce integration error may therefore be especially useful in patients with large LA volume. 相似文献
70.