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51.
Stefano Pini Valéria de Queiroz Daniel Pagnin Lukas Pezawas Jules Angst Giovanni B Cassano Hans-Ulrich Wittchen 《European neuropsychopharmacology》2005,15(4):425-434
A literature search, supplemented by an expert survey and selected reanalyses of existing data from epidemiological studies was performed to determine the prevalence and associated burden of bipolar I and II disorder in EU countries. Only studies using established diagnostic instruments based on DSM-III-R or DSM-IV, or ICD-10 criteria were considered. Fourteen studies from a total of 10 countries were identified. The majority of studies reported 12-month estimates of approximately 1% (range 0.5-1.1%), with little evidence of a gender difference. The cumulative lifetime incidence (two prospective-longitudinal studies) is slightly higher (1.5-2%); and when the wider range of bipolar spectrum disorders is considered estimates increased to approximately 6%. Few studies have reported separate estimates for bipolar I and II disorders. Age of first onset of bipolar disorder is most frequently reported in late adolescence and early adulthood. A high degree of concurrent and sequential comorbidity with other mental disorders and physical illnesses is common. Most studies suggest equally high or even higher levels of impairments and disabilities of bipolar disorders as compared to major depression and schizophrenia. Few data are available on treatment and health care utilization. 相似文献
52.
53.
Bisphenol A release from orthodontic adhesives measured in vitro and in vivo with gas chromatography
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55.
Wearable monitors for patients following discharge from an intensive care unit: practical lessons learnt from an observational study
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![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
56.
Leonardo Silva de Araujo Fernanda Carvalho de Queiroz Mello Nidai de Bárbara Moreira da Silva Janaina Aparecida Medeiros Leung Silvia Maria Almeida Machado Isabela Gama Sardella Renata de Moraes Maciel Maria Helena Féres Saad 《Clinical and Vaccine Immunology : CVI》2014,21(4):552-560
The PstS1 antigen is highly immunogenic, principally when combined with CFP10 during both latent and active TB infection. In the present study, a selected pstS1 gene fragment was cloned, fused with CFP10, and expressed in Escherichia coli. The product [PstS-1(285-374):CFP10] was compared to the recombinant fused RD1 (region of deletion 1) protein (ESAT-6:CFP10) in detecting Mycobacterium tuberculosis infection in 108 recent contacts of pulmonary tuberculosis (TB) cases, considering a positive tuberculin skin test (TST) to be the baseline. The release of gamma interferon (IFN-γ) in 22-h whole-blood and 5-day lymphocyte stimulation assays primed with each antigen was determined. All contacts were clinically followed for up to 1 year, and 87% of the tuberculin skin test-positive (TSTpositive) patients accepted preventative treatment. Concerning the IFN-γ response to PstS-1(285-374):CFP10 in the 22-h and 5-day assays, a slight increase in contact-TSTpositive detection was observed (23/54 and 26/54) compared to the level seen with the RD1 protein (18/54 and 24/54) whereas in the TSTnegative group, similarly lower numbers (≤5/48) of responders were achieved for both antigens, except for RD1 in the 5-day assay (8/48). By combining the IFN-γ responders to both antigens in the 5-day assays, slightly higher increases in positivity were found in the TSTpositive (32/54) and TSTnegative (10/48) groups. Two of 12 untreated TSTpositive contacts progressed to active TB and were concordantly positive in all assays, except for one contact who lacked positivity in the RD1 5-day assay. We demonstrated for the first time that PstS-1(285-374):CFP10 slightly increased contact positivity and detection of active disease progression, suggesting its potential application as a TB infection marker. 相似文献
57.
Exploring the association between genetic and environmental factors and molar incisor hypomineralization: evidence from a twin study
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![点击此处可从《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Rafael José Pio Barbosa Teixeira Natália Silva Andrade Lisanca Carvalho Cavalcante Queiroz Fausto Medeiros Mendes Marcoeli Silva Moura Lúcia de Fátima Almeida de Deus Moura Marina Deus Moura Lima 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2018,28(2):198-206
58.
Nagaraja Moorthy DM Rajiv Ananthakrishna DM Dattatreya P. V. Rao DM Satvic C. Manjunath DM Manjunath C. Nanjappa DM 《Echocardiography (Mount Kisco, N.Y.)》2018,35(3):388-390
Intermittent dysfunction of mechanical mitral valve prosthesis is an uncommon condition. It carries serious clinical implications if unrecognized. Here, we present a case of a 28‐year‐old female with a history of rheumatic multivalvular disease, for which she had undergone double valve replacement and tricuspid annuloplasty. Six months later, she presented with heart failure. Clinical examination revealed intermittent loss of closing clicks followed by a pansystolic murmur at the apex, suggestive of mitral prosthetic valve dysfunction. We highlight the echocardiographic findings of paroxysmal mitral valvular regurgitation secondary to prosthetic valve malfunction secondary to prosthetic valve thrombosis. 相似文献
59.
Ana Dorcas de Melo Inagaki Cristina Gardonyi Carvalheiro Rosana Cipolotti Ricardo Queiroz Gurgel Dayse Alves Rocha Kariny Souza Pinheiro Raquel Melo Araújo Dorothy Ribeiro Resende Lima Jacques Leon Winandy Marisa Márcia Mussi‐Pinhata 《Tropical medicine & international health : TM & IH》2012,17(11):1349-1355
Objectives To estimate, by neonatal screening, the birth prevalence of congenital toxoplasmosis among live‐born infants in Sergipe state, Brazil, and to investigate the clinical features of affected infants. Methods Dried blood spot specimens obtained from 15 204 neonates were assayed for the presence of anti‐T. gondii IgM antibodies. Duplicate retesting was done in infants with positive and borderline results. Confirmatory testing in peripheral blood samples consisted of testing for anti‐T. gondii IgG and IgM in infants and mothers. Those with possible congenital toxoplasmosis were evaluated and followed up to a median age of 20 months. Congenital infection was confirmed in the presence of persisting anti‐T. gondii IgG antibodies beyond 12 months of age. All infants with confirmed infection were treated with pyrimethamine, sulfadiazine and folinic acid for 1 year. Results Fifty‐three infants had detectable IgM in dried blood spot specimens. Confirmatory testing was reactive in 39/50, of which, 38 completed follow‐up. Six of 15 204 newborns were diagnosed with congenital toxoplasmosis, resulting in an estimated birth prevalence of four per 10 000 [CI 95% 1.4–8.0]. Four infants (67%) showed signs of congenital toxoplasmosis in their first year of life; three (75%) had retinochoroidal scars, and one had cerebral calcifications. Two infants remained asymptomatic until 20 months of age. Conclusions The birth prevalence of congenital toxoplasmosis is high in the Brazilian state of Sergipe, with most of the infants showing ocular lesions. Preventive measures are strongly warranted. 相似文献
60.
Danielly Cunha Araújo Ferreira PhD Student Raquel Assed Bezerra da Silva PhD Kranya Victoria Díaz‐Serrano PhD Alexandra Mussolino de Queiroz PhD Carolina Paes Torres Mantovani PhD Andiara De Rossi PhD 《Special care in dentistry》2016,36(1):53-56
The aim of this study is to describe the use of an intraoral assistive technology for a patient with idiopathic generalized muscular dystonia, presenting temporomandibular disorder and severe anterior tooth mobility and diastema. A multidisciplinary team developed an intraoral device to provide typing and painting functions, and promote relaxation of masticatory muscles without compromising the teeth and supporting tissue structures. The occlusal splint associated with the device promoted muscle relaxation and relief of the signs and symptoms of temporomandibular dysfunction, in this case with generalized muscle dystonia, allowing typing and painting with her mouth without causing tooth mobility or occlusal alteration. This intraoral device has low cost, easy adaptation and was efficient in TMD symptoms. Furthermore, the patient returned to her rehabilitation allowing performance of her duties without compromising dental structures, facilitating the social and the digital inclusion. 相似文献