Pneumocystis carinii pneumonia in a Yorkshire terrier dog.

A 14-month-old male Yorkshire terrier was presented to the Autonomous University of Barcelona Veterinary Teaching Hospital because of a history of chronic non-productive cough and acute dyspnea. A follow-up radiograph revealed a diffuse, bilaterally interstitial-alveolar lung disease with presence of air bronchograms. The dog died 5 h after admission with severe dyspnea. Histological sections of the necropsy specimens revealed the presence of characteristic Pneumocystis carinii cysts within alveolar spaces. A diagnosis of P. carinii pneumonia (PCP) was made on the basis of these results. To our knowledge, PCP has not been described in a Yorkshire terrier dog.     

Antidepressant drugs given repeatedly increase the behavioural effects of methoxamine

In this study we investigated the effect of imipramine, citalopram and mianserin on behavioural effects of methoxamine, an α₁-adrenoceptor agonist, in the rat. Methoxamine (25 and 50 m?g) given into the brain lateral ventricle, increases the exploratory activity assessed in the open field test (time of walking, ambulatory activity, rearing ⁺ peeping). The studied antidepressants, administered repeatedly (10 mg/kg p.o., twice daily, 14 days) but not in single doses, enhance the above effects of methoxamine. The results provide further arguments for the hypothesis that antidepressant drugs administered repeatedly induce a functional α₁-adrenoceptor up-regulation.     

Jenctlonal Epidermolysis Bullosa, Pyloric Atresia, and Genitourinary Disease

The occasional concurrence of junctional epidermolysis bullosa and pyloric atresia has been documented in the literature. Several infants reported as having this combined disorder were also noted to have significant genitourinary disease. We treated a 4 1/2-year-old boy with mild cutaneous manifestations of junctional epidermolysis bullosa, corrected pyloric atresia, and significant renal disease secondary to recurrent obstruction of the ureterovesical junction.     

Elastofibroma dorsi as a cause of shoulder pain or snapping scapula.

Elastofibroma dorsi is a benign soft tissue tumor, not well-known because of its low incidence, located in the chest wall in the subscapular area. In 10 patients with elastofibroma dorsi, the clinical symptoms were snapping scapula or shoulder pain. In three of the patients, the previous diagnosis was shoulder impingement, and the patients were treated without success. The clinical diagnosis was confirmed by magnetic resonance imaging. Surgical treatment resolved the symptoms in all patients. This tumor should be considered in the differential diagnosis of snapping scapula or shoulder impingement.