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61.
The purpose of this in vitro study was to evaluate two commonly used gutta-percha solvents for their effectiveness in dissolving several types of root canal sealers. Seven different sealers (AH26, AH Plus, Diaket, Roekoseal, Sankin Apatite Root Sealer, Sealapex, and Sultan U/P) were used in this study. After mixing according to the manufacturers' directions, each material was syringed into 30 glass capillary tubes, and a total of 210 tubes were placed in a humidifier at 37 degrees C for one week to allow the materials to set completely. Each group of 30 tubes, obturated with one type of sealer, was then randomly divided into three subgroups, including 10 tubes each. Chloroform was used in the first ten tubes from each sealer group. Halothane was used for the second group. In the last group, the sealer was removed with files, without using any solvent. The time necessary to pass a file through to the end of the tube was recorded for each sample in seconds. Results were analyzed using one-way analysis of variance. Sealapex did not set at all unless in contact with air. Roekoseal did not adhere to the glass capillary tubes, and was therefore easily removed from the tube in all samples. AH26 and AH Plus root canal sealers tightly adhered to the tube walls, so none of the techniques were effective in removing them from the tubes within 30 min. Diaket root canal sealer was easily removed using solvents (P < 0.05). There was no advantage in using solvents to remove Sankin Apatite Root Sealer (P > 0.05). Solvents were found to be very effective in dissolving the Sultan U/P root canal sealer (P < 0.05). 相似文献
62.
Comparison of secondary implantation of flexible open-loop anterior chamber and scleral-fixated posterior chamber intraocular lenses 总被引:7,自引:0,他引:7
Evereklioglu C Er H Bekir NA Borazan M Zorlu F 《Journal of cataract and refractive surgery》2003,29(2):301-308
PURPOSE: To analyze and compare the outcomes and complication rates of secondary implantation of flexible, open-loop, anterior chamber intraocular lenses (AC IOLs) and single-piece, scleral-fixated, posterior chamber IOLs (PC IOLs). SETTING: Departments of Ophthalmology, Gaziantep University Medical Faculty, Research Hospital, Gaziantep, and In?nü University Medical Faculty, Research Hospital, Malatya, Turkey. METHODS: This study comprised 124 eyes of 113 aphakic patients (61 men, 52 women) with insufficient capsule support who had secondary IOL implantation from January 1997 to June 2001. In Group 1 (n = 73 eyes), a flexible, open-loop AC IOL was implanted and in Group 2 (n = 51 eyes), a single-piece, scleral-fixated PC IOL. The mean follow-up was 34 months (range 6 to 53 months) and took place at several different clinical settings. The mean interval between the initial cataract operation and secondary IOL implantation was 63 months (range 6 months to 12 years). The postoperative outcomes, safety, efficacy, and complication rates were analyzed, and the preoperative and postoperative best spectacle-corrected visual acuities (BSCVAs) were compared. RESULTS: The postoperative mean BSCVA was 20/34.8 +/- 45.2 (SD) in Group 1 and 20/32.1 +/- 33.7 in Group 2; the difference was not significant (P =.718). A BSCVA of 20/40 or better was achieved in 62 eyes (84.9%) in Group 1 and 45 eyes (88.2%) in Group 2. A BSCVA of 20/25 or better was achieved in 40 eyes (54.8%) and 33 eyes (64.7%), respectively. The difference between the 2 groups was not significant (P =.472). Complications occurred in 25 eyes (34.2%) in Group 1 and 13 eyes (25.5%) in Group 2 (P >.05). The most frequent complications in Group 1 were early transient corneal edema, intraocular pressure elevation, cystoid macular edema, hyphema, secondary glaucoma, and iris capture or pupil decentration and in Group 2, suture erosion, a tilted or decentered IOL, fibrin reaction, and vitreous prolapse into the anterior chamber. CONCLUSIONS: The AC IOLs and PC IOLs were safe and effective for secondary implantation to correct aphakia. Secondary implantation of the scleral-fixated PC IOL seemed to provide a more favorable outcome and a lower complication rate than the open-loop AC IOL in complicated cataract cases with inadequate capsule and zonular support. As scleral-fixated PC IOL implantation is technically more difficult than AC IOL implantation, the decisive factor in choosing a secondary IOL is surgical experience. Long-term comparison of both techniques is required. 相似文献
63.
Ertas M Baykan B Orhan EK Zarifoglu M Karli N Saip S Onal AE Siva A 《The journal of headache and pain》2012,13(2):147-157
Several studies have shown that the prevalence of migraine and tension-type headache (TTH) varied between different geographical
regions. Therefore, there is a need of a nationwide prevalence study for headache in our country, located between Asia and
Europe. This nationwide study was designed to estimate the 1-year prevalence of migraine and TTH and analyse the clinical
features, the impact as well as the demographic and socio-economic characteristics of the participant households in Turkey.
We planned to investigate 6,000 representative households in 21 cities of Turkey; and a total of 5,323 households (response
rate of 89%) aged between 18 and 65 years were examined for headache by 33 trained physicians at home on the basis of the
diagnostic criteria of the second edition of the International Classification of Headache Disorders (ICHD-II). The electronically
registered questionnaire was based on the headache features, the associated symptoms, demographic and socio-economic situation
and history. Of 5,323 participants (48.8% women; mean age 35.9 ± 12 years) 44.6% reported recurrent headaches during the last
1 year and 871 were diagnosed with migraine at a prevalence rate of 16.4% (8.5% in men and 24.6% in women), whereas only 270
were diagnosed with TTH at a prevalence rate of 5.1% (5.7% in men and 4.5% in women). The 1-year prevalence of probable migraine
was 12.4% and probable TTH was 9.5% additionally. The rate of migraine with aura among migraineurs was 21.5%. The prevalence
of migraine was highest among 35–40-year-old women while there were no differences in age groups among men and in TTH overall.
More than 2/3 of migraineurs had ever consulted a physician whereas only 1/3 of patients with TTH had ever consulted a physician.
For women, the migraine prevalence was higher among the ones with a lower income, while among men, it did not show any change
by income. Migraine prevalence was lower in those with a lower educational status compared to those with a high educational
status. Chronic daily headache was present in 3.3% and the prevalence of medication overuse headache was 2.1% in our population.
There was an important impact of migraine with a monthly frequency of 5.9 ± 6, and an attack duration of 35.1 ± 72 h, but
only 4.9% were on prophylactic treatment. The one-year prevalence of migraine estimated as 16.4% was similar or even higher
than world-wide reported migraine prevalence figures and identical to a previous nation-wide study conducted in 1998, whereas
the TTH prevalence was much lower using the same methodology with the ICHD-II criteria. 相似文献
64.
Atakan Sezer Ahmet Rahmi Hatipoglu Ufuk Usta Gülay Altun Necdet Sut 《Current therapeutic research》2010,71(2):118-128
Background: Hydatid disease is a worldwide health problem. Treatment is surgical or percutaneous, using scolicidal agents. Caustic sclerosing cholangitis might develop after the contact of scolicidal agents with the biliary ducts. Melatonin, an antioxidant, anti-inflammatory, and anticarcinogenic agent, might be used in the treatment of caustic sclerosing cholangitis due to its possible preventive effects on fibrosis and cell damage.Objective: The aim of the study was to investigate the effects of melatonin on an experimentally developed caustic sclerosing cholangitis with scolicidal solution (formalin) in a rat model.Methods: Forty female Sprague-Dawley rats aged 11 to 13 weeks and weighing 250 ± 30 g were randomly assigned to 1 of 4 groups of 10: formalin 5% at 0.5 mL/d + melatonin placebo; formalin placebo + intraperitoneal melatonin 10 mg/kg/d; formalin 5% at 0.5 mL/d + melatonin 10 mg/kg/d; and formalin placebo and melatonin placebo (control). Hepatobiliary function was assessed using dynamic scintigraphy with technetium-99m-mebrofenin on study day 60. The histology of the liver and biliary duct specimens was examined on study day 60. In each group, histopathologic alterations were scored as absent, slight, mild, or severe.Results: Mean severity scores for parenchymal necrosis in the liver (P < 0.01), portal fibrosis (P < 0.01), biliary duct proliferation (P < 0.001), cholangitis/ pericholangitis (P < 0.01), hyperemia in the biliary ducts (P < 0.01), and fibrosis (P < 0.01) were significantly lower in rats treated with formalin + melatonin compared with those treated with formalin alone. No significant differences were observed between the 3 treatment groups with respect to t½, a parameter used to assess the secretion function of the hepatocytes. However, the t½ was significantly longer in the treatment groups compared with controls (P < 0.001).Conclusion: In this experimental study in a rat model of caustic sclerosing cholangitis, the histopathologic and scintigraphic findings suggested that melatonin is effective in attenuating the damage caused by scolicidal agents on the liver and biliary ducts. 相似文献
65.
Fazil Necdet Ardiç MD ?ebnem Aktan MD Cüneyt Orhan Kara MD Berna ?anli MD 《American journal of otolaryngology》1998,19(6):365
Purpose: To investigate the activities of inner ear melanin in patients with pigment variations and disorders. Our purpose was to find evidence on the effects of melanin-containing cells by measuring the high-frequency threshold and the latency of stapes reflex in patients with vitiligo.Patients and Methods: Twenty-nine patients with active vitiligo and 41 healthy subjects were included in this study. Pure tone thresholds were determined at frequencies between 250 and 16,000 Hz. Ipsilateral and contralateral stapes reflexes were measured at 1,000, 2,000, and 4,000 Hz. After we compared the results in the control and vitiligo groups by using the Mann-Whitney U test for each frequency, we compared women and men separately to eliminate gender differences.Results: Pure tone thresholds of the vitiligo group were significantly lower than the control group at 4,000, 6,000, 8,000 and 10,000 Hz (P < .05). The statistically different thresholds were 8,000 and 10,000 Hz in women, compared with 4,000, 6,000, 8,000, 10,000, 12,500, and 16,000 Hz in men (P < 0.05). Reflex latencies for the two groups were not statistically different.Conclusion: Vitiligo, which is a type of pigment disorder, seems to be an effective factor in hearing loss, and men are more susceptible to it than women. The mechanism for this condition might be the absence of the preventive function of melanin-containing cells in the inner ear. 相似文献
66.
67.
68.
Cemil Caliskan Necdet Guler Can Karaca Ozer Makay Ozgur Firat Mustafa A. Korkut 《The Indian journal of surgery》2010,72(3):243-248
Background and aims
Colorectal carcinoma (CRC) is the most frequent malignancy of the gastrointestinal tract. Prognostic researches are carried out for choosing the optimum therapy, evaluating therapy results and comparing multicentre results for better qualification in the therapy of the disease. 相似文献69.
70.
Hasan Pekdemir Dilek Cicek Ahmet Camsari M. Necdet Akkus V. Gokhan Cin Oben Doven H. Tuncay Parmaksiz M. Tuna Katircibasi I. Turkay Ozcan 《Annals of noninvasive electrocardiology》2004,9(1):24-33
Background: Coronary slow flow (CSF) is characterized by delayed opacification of coronary arteries in the absence of epicardial occlusive disease. In this study, we aimed to determine endothelin‐1 (ET‐1), nitric oxide (NOx) levels and time domain heart rate variability (HRV) parameters in patients with CSF and relationship among these parameters. Methods: Thirty‐three patients with CSF detected in the coronary angiography (17 females; mean age 55 ± 7) and 19 patients with normal coronary flow (10 females; mean age 54 ± 11) as a control group were enrolled in the study. Patients were divided into two groups according to exercise testing as if positive (group A, n = 8) or negative (group B, n = 25). Results: Plasma ET‐1 levels were higher in the group A patients (28.7 ± 17.4 pg/ml) than that of group B (15.9 ± 10.6 pg/ml) and control group (6.0 ± 5.7 pg/ml); and higher in group B patients than that of control group (P < 0.05). Although groups A and B did not differ according to plasma NOx levels (23.4 ± 13.5 μmol/L vs. 32.8 ± 22.7 μmol/L, P > 0.05), NOx levels in group A were lower than the control group (23.4 ± 13.5 μmol/L versus 42.5 ± 15.9 μmol/L, P < 0.05). Time domain HRV parameters were decreased in all patient groups. This was more prominent in group A. Additionally, HRV parameters were negatively correlated with ET‐1 and TIMI frame counts. TIMI frame count was also significantly correlated with ET‐1 and NOx levels (r = 0.61, P < 0.0001, r =?0.30, P < 0.05). Upon intravascular ultrasonography investigation, the common finding was longitudinally extended massive calcification throughout the epicardial arteries. Mean intimal thickness was 0.50 ± 0.13 mm (group A; 0.58 ± 0.11 mm, group B 0.47 ± 0.12 mm, P = 0.029). Conclusions: The present study demonstrated that in patients with CSF, both increased plasma ET‐1, decreased plasma NOx and diffuse atherosclerosis may cause the decrease in HRV by effecting myocardial blood flow. 相似文献