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排序方式: 共有8333条查询结果,搜索用时 15 毫秒
961.
The 1-g 14C-D-xylose breath test in gallstone patients with and without duodenal diverticula 总被引:1,自引:0,他引:1
To assess whether gallstone patients with duodenal diverticula have bacterial overgrowth in the proximal small bowel, the results of the 1-g 14C-D-xylose breath test were compared in 24 patients with duodenal diverticula and in 24 without diverticula. All patients had been treated with endoscopic papillotomy (EPT) for stones in the common bile duct before the study, and cholecystectomy had previously been performed in 20 patients. No significant differences between the groups were found concerning age, sex, and body weight. Cumulative 14CO2 expired in 3 h in percentage of administered dose of 14C-D-xylose was 8.55% (7.58-9.57%) and 7.38% (6.32-8.96%) in patients with and without diverticula, respectively (p = 0.06), indicating a higher bacterial activity in the small bowel in patients with duodenal diverticula than in those without diverticula. The results appeared to be influenced by cholecystectomy. 相似文献
962.
Jan Carstens Henning Gr?nb?k Helle K Larsen Erling B Pedersen Hendrik Vilstrup 《BMC gastroenterology》2007,7(1):1
Background
Sodium retention and ascites are serious clinical problems in cirrhosis. Urodilatin (URO) is a peptide with paracrine effects in decreasing sodium reabsorption in the distal nephron. Our aim was to investigate the renal potency of synthetic URO on urine sodium excretion in cirrhosis patients with sodium retention and ascites. 相似文献963.
Relationship of overweight to hiatus hernia and reflux oesophagitis 总被引:14,自引:0,他引:14
G Stene-Larsen R Weberg I Fr?yshov Larsen O Bj?rtuft B Hoel A Berstad 《Scandinavian journal of gastroenterology》1988,23(4):427-432
In a prospective study in 1224 patients referred for upper alimentary endoscopy, reflux oesophagitis was found in 195 (16%) of the patients and hiatus hernia in 249 (20%). In patients with reflux oesophagitis a coexisting hiatus hernia was found in 68%. The weight-for-height index (W/H1.8), which expresses the degree of overweight, was significantly higher both in patients with hiatus hernia and in the patients with reflux oesophagitis, indicating an overweight of approximately 5% in both groups. The overweight was most pronounced in oesophagitis grades 1 and 2, whereas in patients with severe oesophagitis (grade 3) body weight was normal, possibly owing to weight loss caused by dysphagia and excessive regurgitation. The results support the view that adiposity is associated with both sliding hiatus hernia and reflux oesophagitis and that hiatus hernia plays a role in the development of reflux oesophagitis. 相似文献
964.
Amir M Khan Kevin P Lally Gary L Larsen Giuseppe N Colasurdo 《Pediatric pulmonology》2002,33(2):111-116
Meconium aspiration syndrome (MAS) is a cause of significant morbidity and mortality in the perinatal period. Despite the clinical relevance of MAS, its pathogenesis is poorly understood. Epithelial cell-derived prostanoids are involved in the regulation of several cellular functions within the lung, including the control of tone and reactivity of airway and vascular smooth muscle. In this study, we evaluated whether exposure to meconium affects the metabolic function of human airway epithelial cells. Monolayers of A549 cells, a transformed human epithelial cell line, were incubated with various concentrations of meconium. Control cells were incubated with serum-free medium in a similar manner. The supernatant fluid was removed at various time points and assayed for thromboxane A(2) (TXA(2)) production. The latter was accomplished by measuring its immediate and stable metabolite thromboxane B(2), using an enzyme-linked immunosorbent assay (ELISA). In selected experiments, the modulatory effects of indomethacin (10(-6) M), dexamethasone (10(-6) M), and L-nitroarginine methyl ester (L-NAME, 10(-6) M) on TXA(2) production were evaluated. Results were expressed in terms of pg/mg protein (mean +/- SE). We found that exposure to meconium produced a significant release of TXA(2) from A549 cells. Indomethacin, dexamethasone, and in part, L-NAME inhibited meconium-induced release of TXA(2). Our findings demonstrate that meconium enhances the production of thromboxanes from A549 cells, suggesting that airway epithelial cells and their metabolic products may play an important role in the pathogenesis of MAS. 相似文献
965.
Dørup J Schacht Hansen M Riisgaard Ribe L Larsen K 《Medical informatics and the Internet in medicine》2002,27(4):281-289
Static web pages may be easy to setup using text processors or user-friendly web editing software. However, some basic knowledge of the implementation (HTML) is usually needed for final editing and maintenance. As a result many static web pages are left without appropriate updating. With a database driven, dynamic approach web contents may change through user interaction, the pages are usually easier to maintain, and design elements are separated from contents. Database driven solutions (or content management systems) for larger organizations may be purchased at many different levels of complexity. For smaller systems, such as separate courses or projects, they may, however, be developed locally. The present study compares four alternative technologies for database driven web pages. Each technology offers advantages and disadvantages and many issues need to be considered when selecting platform. The present study demonstrates that database driven web pages may be effectively deployed using free Open Source software. Details may be found at www.intermed.dk/datadriven. 相似文献
966.
967.
Lack of ability to synthesize tissue factor by endothelial cells in intact human saphenous veins 总被引:1,自引:0,他引:1
It is well established that cultured endothelial cells are induced to generate tissue factor activity when incubated with either endotoxin or thrombin. In this study a perfusion system was used on 3-4 cm long human saphenous veins. The veins were perfused with thrombin (2.5 U/ml), endotoxin (30 ng/ml) or just medium for 3 h at 37 degrees C. After the perfusion, the veins were treated with collagenase, and EC were collected and subjected to tissue factor activity measurements. Some perfused veins were examined for tissue factor activity on the vessel wall by allowing factor VII and factor X to interact with the lumen of the intact vessels, followed by quantitation of generated factor Xa in a chromogenic assay. No formation of tissue factor activity could be found after perfusion in either collagenase-dissolved endothelial cells or in the coupled chromogenic assay for tissue factor activity performed in the lumen of the vessel. Our data strongly suggest that endothelial cells in intact endothelium may behave quite differently from isolated endothelial cells stimulated in cell cultures. 相似文献
968.
TeriSue Smith-Jackson Mary V. Brown Matthew Flint Merilee Larsen 《Journal of diabetes and its complications》2018,32(11):1051-1055
Aims
This study examined delayed type one diabetes (T1D) diagnosis, along with the associated severity markers, in the United States. Qualitative reflection was explored to add depth of understanding.Methods
975 parents of a minor child with T1D were recruited through snowball, social media requests to complete a 55-question online survey on the experience of diagnosis.Results
34% of children with T1D had a delayed diagnosis. When compared to those without a delayed diagnosis, these children were more likely to have an Emergency Room diagnosis (39.8% vs. 24.6%), be transported by ambulance or life flight (30.7% vs. 15.3%), be hospitalized (93.7% vs. 83.9%), spend time in an Intensive Care Unit (42.2% vs. 21.3%), and be in diabetic ketoacidosis (DKA) (42.2% vs. 21.3%). Younger children were at increased risk, with higher rates of DKA and fewer days of symptoms. Many parents experienced frustration receiving a prompt diagnosis for their child, including an inability to schedule a physician appointment, proper glucose testing, and concerns being dismissed by professionals.Conclusion
More physician and parent education is needed. Doctors should conduct glucose screenings when diabetes symptoms are present. Parents need education to recognize excessive thirst and frequent urination as reasons to seek medical treatment. 相似文献969.