全文获取类型
收费全文 | 201071篇 |
免费 | 3288篇 |
国内免费 | 54篇 |
专业分类
耳鼻咽喉 | 1409篇 |
儿科学 | 7584篇 |
妇产科学 | 3819篇 |
基础医学 | 19829篇 |
口腔科学 | 2017篇 |
临床医学 | 15548篇 |
内科学 | 35323篇 |
皮肤病学 | 1056篇 |
神经病学 | 18944篇 |
特种医学 | 9837篇 |
外国民族医学 | 2篇 |
外科学 | 31632篇 |
综合类 | 2791篇 |
一般理论 | 18篇 |
预防医学 | 21431篇 |
眼科学 | 3089篇 |
药学 | 11082篇 |
1篇 | |
中国医学 | 660篇 |
肿瘤学 | 18341篇 |
出版年
2023年 | 216篇 |
2022年 | 367篇 |
2021年 | 815篇 |
2020年 | 526篇 |
2019年 | 820篇 |
2018年 | 22733篇 |
2017年 | 17934篇 |
2016年 | 20052篇 |
2015年 | 1597篇 |
2014年 | 1794篇 |
2013年 | 2100篇 |
2012年 | 8775篇 |
2011年 | 22930篇 |
2010年 | 19733篇 |
2009年 | 12374篇 |
2008年 | 20827篇 |
2007年 | 23126篇 |
2006年 | 1891篇 |
2005年 | 3444篇 |
2004年 | 4499篇 |
2003年 | 5353篇 |
2002年 | 3440篇 |
2001年 | 737篇 |
2000年 | 827篇 |
1999年 | 530篇 |
1998年 | 392篇 |
1997年 | 362篇 |
1996年 | 243篇 |
1995年 | 257篇 |
1994年 | 225篇 |
1993年 | 184篇 |
1992年 | 356篇 |
1991年 | 355篇 |
1990年 | 391篇 |
1989年 | 354篇 |
1988年 | 260篇 |
1987年 | 243篇 |
1986年 | 227篇 |
1985年 | 244篇 |
1984年 | 185篇 |
1983年 | 150篇 |
1982年 | 137篇 |
1981年 | 99篇 |
1980年 | 123篇 |
1979年 | 200篇 |
1978年 | 159篇 |
1977年 | 110篇 |
1974年 | 152篇 |
1973年 | 109篇 |
1970年 | 118篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
11.
Valerie Iles 《Health care analysis》2016,24(2):105-118
This paper takes a somewhat slant perspective on flourishing and care in the context of suffering, death and dying, arguing that care in this context consists principally of ‘acts of work and courage that enable flourishing’. Starting with the perception that individuals, society and health care professionals have become dulled to death and the process of dying in Western advanced health systems, it suggests that for flourishing to occur, both of these aspects of life need to be faced more directly. The last days of life need to be ‘undulled’. Reflections upon the experiences of the author as carer and daughter in the face of her mother’s experience of death are used as basis for making suggestions about how care systems and professionals might better assist people in dealing with ‘the most grown up thing’ humans ever do, which is to die. 相似文献
12.
13.
14.
Henry Havel Gregory Finch Pamela Strode Marc Wolfgang Stephen Zale Iulian Bobe Hagop Youssoufian Matthew Peterson Maggie Liu 《The AAPS journal》2016,18(6):1373-1378
Advancing nanomedicines from concept to clinic requires integration of new science with traditional pharmaceutical development. The medical and commercial success of nanomedicines is greatly facilitated when those charged with developing nanomedicines are cognizant of the unique opportunities and technical challenges that these products present. These individuals must also be knowledgeable about the processes of clinical and product development, including regulatory considerations, to maximize the odds for successful product registration. This article outlines these topics with a goal to accelerate the combination of academic innovation with collaborative industrial scientists who understand pharmaceutical development and regulatory approval requirements—only together can they realize the full potential of nanomedicines for patients. 相似文献
15.
16.
M. Alexandra Friedman Charlotte M. Niznik Janelle R. Bolden Lynn M. Yee 《Journal of community health》2016,41(2):354-358
While peer support has been investigated in multiple clinical contexts, its application to the postpartum setting is unknown. The aim was to assess acceptability of a postpartum peer support program for women with diabetes. Observational survey-based needs assessment of forty low-income women with diabetes, receiving care at a major medical institution. Mean age and gravidity were 30.7 years and 3.15 ± 1.67 respectively. 45 % expressed interest in a “buddy.” There was no significant difference between groups desiring and not desiring this program. A majority of respondents desired telephone, text messaging, and in-person contacts (79.2, 72.1, 83.8 %), with 72.5 % of patients desiring diabetes-related activities during clinic waiting time. Many women desire a postpartum diabetes reciprocal peer program for support outside of clinician visits. Patients are receptive to educational services during their wait and outside of clinic time, a potentially valuable opportunity to share important health information. 相似文献
17.
18.
Molly Orcutt Wendy C. King Melissa A. Kalarchian Michael J. Devlin Marsha D. Marcus Luis Garcia Kristine J. Steffen James E. Mitchell 《Surgery for obesity and related diseases》2019,15(2):295-303
Background
A history of childhood maltreatment and psychopathology are common in adults with obesity.Objectives
To report childhood maltreatment and to evaluate associations between severity and type of childhood maltreatment and lifetime history of psychopathology among adults with severe obesity awaiting bariatric surgery.Setting
Four clinical centers of the Longitudinal Assessment of Bariatric Surgery Research Consortium.Methods
The Childhood Trauma Questionnaire, which assesses presence/severity (i.e., none, mild, moderate, severe) of physical abuse, mental abuse, physical neglect, mental neglect, and sexual abuse, was completed by 302 female and 66 male bariatric surgery patients. Presurgery lifetime history of psychopathology and suicidal ideation/behavior were assessed with the Structured Clinical Interview for DSM-IV and the Suicidal Behavioral Questionnaire-Revised, respectively. Presurgery lifetime history of antidepressant use was self-reported.Results
Two thirds (66.6%) of females and 47.0% of males reported at least 1 form of childhood trauma; 42.4% and 24.2%, respectively, at greater than or equal to moderate severity. Among women, presence/greater severity of childhood mental or physical abuse or neglect was associated with a higher risk of history of psychopathology (i.e., major depressive disorder, posttraumatic stress disorder, other anxiety disorder, alcohol use disorder, binge eating disorder), suicidal ideation/behavior and antidepressant use (P for all ≤ .02). These associations were independent of age, race, education, body mass index, and childhood sexual abuse. Childhood sexual abuse was independently associated with a history of suicidal ideation/behavior and antidepressant use only (P for both ≤ .05). Statistical power was limited to evaluate these associations among men.Conclusion
Among women with obesity, presence/severity of childhood trauma was positively associated with relatively common psychiatric disorders. 相似文献19.
Konrad Matyja Anna Małachowska-Jutsz Anna K. Mazur Kazimierz Grabas 《Ecotoxicology (London, England)》2016,25(5):924-939
Dehydrogenase activity is frequently used to assess the general condition of microorganisms in soil and activated sludge. Many studies have investigated the inhibition of dehydrogenase activity by various compounds, including heavy metal ions. However, the time after which the measurements are carried out is often chosen arbitrarily. Thus, it can be difficult to estimate how the toxic effects of compounds vary during the reaction and when the maximum of the effect would be reached. Hence, the aim of this study was to create simple and useful mathematical model describing changes in dehydrogenase activity during exposure to substances that inactivate enzymes. Our model is based on the Lagergrens pseudo-first-order equation, the rate of chemical reactions, enzyme activity, and inactivation and was created to describe short-term changes in dehydrogenase activity. The main assumption of our model is that toxic substances cause irreversible inactivation of enzyme units. The model is able to predict the maximum direct toxic effect (MDTE) and the time to reach this maximum (TMDTE). In order to validate our model, we present two examples: inactivation of dehydrogenase in microorganisms in soil and activated sludge. The model was applied successfully for cadmium and copper ions. Our results indicate that the predicted MDTE and TMDTE are more appropriate than EC50 and IC50 for toxicity assessments, except for long exposure times. 相似文献
20.