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31.
32.
Muhammad Mutasim Billah Tufail Asad Shamim Asghar Ali Muhammad Ibrahim Danial Mehdi Waseem Nawaz 《AIMS Public Health》2022,9(2):440
The health care delivery system in Pakistan is in a process of rapid growth, and it consists of public and private sectors. The provincial government is preliminarily responsible for providing health care facilities within its province except in federally administered areas. In Pakistan, there are three tiers of governmental healthcare delivery systems, which comprise government, semi-government, and parastatal organizations. The purpose of this study is to understand the rapid increase in influx of patients in major city hospitals of the Punjab province. The reasons for patient flow towards the major city areas can vary, but our point of focus is mainly on those patients who are prescribed to get a computed tomography (CT) scan done for better diagnosis and early treatment, including but not limited to roadside accident cases. The study targets the define, measure, analyze, improve and control (DMAIC) problem solving approach to assess the potential cause of CT patient flow and the challenges that the health department is facing to cater to such a patient niche and process while minimizing the congestion in city government hospitals. The approach in this study summarizes with numerous quality tools like Voice of Customer (VOC) which is customer feedback, Customer Output Process Input and Supplier (COPIS) processes use for high-level process map to know what your customer value, Approver Resource Member Interested (ARMI) chart which is use to analyze the stakeholders on management of the project, evaluation with the help of fishbone diagram and house of quality, and for process improvement methodology we use the team brainstorming technique and the kaizen 5-why technique. The technique came up with an idea of a public-private partnership (PPP) project—partnership between public agency and private firm, as the health care industry in Punjab province is going through budgetary issues. In a PPP project, the Government will allocate the space to a private firm to build the facility on their own and provide quality service for CT scan diagnosis to the public of Punjab. The study identified the top 10 critical factors that the patients have expected from the government to be provided on priority. The Kaizen process improvement methodology has been adopted to provide the possible solution of government budgetary issues. The set of tools in this study can be adopted by other PPP projects to enhance the project performance. 相似文献
33.
Zhang Xu Jung-Hyun Choi David L. Dai Jun Luo Reese Jalal Ladak Qian Li Yimeng Wang Christine Zhang Shane Wiebe Alex C. H. Liu Xiaozhuo Ran Jiaqi Yang Parisa Naeli Aitor Garzia Lele Zhou Niaz Mahmood Qiyun Deng Mohamed Elaish Rongtuan Lin Lara K. Mahal Tom C. Hobman Jerry Pelletier Tommy Alain Silvia M. Vidal Thomas Duchaine Mohammad T. Mazhab-Jafari Xiaojuan Mao Seyed Mehdi Jafarnejad Nahum Sonenberg 《Proceedings of the National Academy of Sciences of the United States of America》2022,119(32)
34.
Five‐year change in refraction and its ocular components in the 40‐ to 64‐year‐old population of the Shahroud eye cohort study
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35.
Khoobi M Emami S Dehghan G Foroumadi A Ramazani A Shafiee A 《Archiv der Pharmazie》2011,344(9):588-594
Coumarin and benzothiazole scaffolds can be found in a number of natural or synthetic antioxidants. In an effort to develop a novel radical scavenger and potential antioxidant, a series of coumarin derivatives containing 2‐methylbenzothiazoline motif and related compounds was synthesized and evaluated for their DPPH (1,1‐diphenyl‐2‐picrylhydrazyl) and ABTS?+ (2,2′‐azinobis(3‐ethylbenzothiazoline‐6‐sulfonic acid) radicals scavenging activities. Among them, 7‐hydroxy‐3‐(2‐methyl‐2,3‐dihydrobenzo[d]thiazol‐2‐yl)‐2H‐chromen‐2‐one ( 3e ) has shown a significant free radical scavenging activity. From the structure–activity point of view, it was found that phenolic coumarin ring and benzothiazoline moiety in target compounds may contribute to the scavenging activity against free radicals. 相似文献
36.
Maryam Noroozian Sina Ghasemi Seyed-Mohammad-Reza Hosseini Amirhossein Modabbernia Mohammad-Reza Khodaie-Ardakani Omid Mirshafiee Mehdi Farokhnia Masih Tajdini Farzin Rezaei Bahman Salehi Mandana Ashrafi Habibeh Yekehtaz Mina Tabrizi Shahin Akhondzadeh 《Psychopharmacology》2013,228(4):595-602
Rational
A growing body of evidence illustrates that 5-HT3 receptor antagonist drugs may be of benefit in the treatment of negative symptoms in schizophrenia.Objective
The objective of this study was to assess the efficacy and tolerability of tropisetron add-on to risperidone on negative symptoms in patients with chronic stable schizophrenia.Methods
In a double-blind, placebo-controlled 8-week trial, 40 patients with chronic schizophrenia who were stabilized on risperidone were randomized into tropisetron or placebo add-on groups. Psychotic symptoms were measured using the Positive and Negative Syndrome Scale (PANSS) every 2 weeks. Furthermore, extrapyramidal and depressive symptoms as well as side effects were assessed. The primary outcome measure was the difference in change from baseline of negative subscale scores between the two groups at week 8.Results
Tropisetron resulted in greater improvement of the total PANSS scores [F(1.860,70.699)?=?37.366, p?<?0.001] as well as negative scores [F(2.439,92.675)?=?16.623, p?<?0.001] and general psychopathology [F(1.767,67.158)?=?4.602, p?=?0.017], but not positive subscale scores [F(1.348, 51.218)?=?0.048, p?=?0.893] compared to placebo. In a multiple regression analysis controlling for positive, extrapyramidal, and depressive symptoms, treatment group (standardized β?=??0.640) significantly predicted changes in primary negative symptoms. The side effect profile did not differ significantly between the two groups.Conclusion
Tropisetron add-on to risperidone improves the primary negative symptoms of patients with chronic stable schizophrenia. 相似文献37.
Meijie Tian Adam T. Cheuk Jun S. Wei Abdalla Abdelmaksoud Hsien-Chao Chou David Milewski Michael C. Kelly Young K. Song Christopher M. Dower Nan Li Haiying Qin Yong Yean Kim Jerry T. Wu Xinyu Wen Mehdi Benzaoui Katherine E. Masih Xiaolin Wu Zhongmei Zhang Sherif Badr Naomi Taylor Brad St. Croix Mitchell Ho Javed Khan 《The Journal of clinical investigation》2022,132(16)
38.
Mahdi Asghari Ozma Amin Abbasi Sousan Akrami Masoud Lahouty Nayyer Shahbazi Khudaverdi Ganbarov Pasquale Pagliano Sahar Sabahi ükran Kse Mehdi Yousefi Sounkalo Dao Mohammad Asgharzadeh Hedayat Hosseini Hossein Samadi Kafil 《Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive》2022,30(2):180
39.
40.
Mehdi Debaibi Asma Sghair Moez Sahnoun Rami Zouari Rime Essid Majdi Kchaou Amen Dhaoui Adnen Chouchen 《Clinical Case Reports》2022,10(5)
Primary retroperitoneal cavernous hemangioma is an extremely rare disease in clinical practice. It is classified as a vascular tumor. Only three cases have been reported in the literature. The diagnosis is uncommon due to the lack of specific radiological features. It becomes symptomatic as a consequence of its enormous size or complications like rupture or compression. We herein report a unique case of primary retroperitoneal cavernous hemangioma treated with conventional surgery in a 35‐year‐old male patient admitted to our department for chronic abdominal pain. Retroperitoneal cavernous hemangioma is an extremely rare vascular tumor in adulthood. Confirmation is made by histopathological examination after total surgical resection. 相似文献