全文获取类型
收费全文 | 8493篇 |
免费 | 435篇 |
国内免费 | 36篇 |
专业分类
耳鼻咽喉 | 62篇 |
儿科学 | 140篇 |
妇产科学 | 113篇 |
基础医学 | 1160篇 |
口腔科学 | 965篇 |
临床医学 | 766篇 |
内科学 | 1745篇 |
皮肤病学 | 163篇 |
神经病学 | 733篇 |
特种医学 | 269篇 |
外科学 | 1222篇 |
综合类 | 27篇 |
一般理论 | 1篇 |
预防医学 | 512篇 |
眼科学 | 205篇 |
药学 | 523篇 |
中国医学 | 56篇 |
肿瘤学 | 302篇 |
出版年
2024年 | 8篇 |
2023年 | 64篇 |
2022年 | 136篇 |
2021年 | 289篇 |
2020年 | 173篇 |
2019年 | 226篇 |
2018年 | 287篇 |
2017年 | 186篇 |
2016年 | 219篇 |
2015年 | 299篇 |
2014年 | 391篇 |
2013年 | 435篇 |
2012年 | 753篇 |
2011年 | 819篇 |
2010年 | 478篇 |
2009年 | 385篇 |
2008年 | 600篇 |
2007年 | 642篇 |
2006年 | 603篇 |
2005年 | 478篇 |
2004年 | 453篇 |
2003年 | 364篇 |
2002年 | 307篇 |
2001年 | 32篇 |
2000年 | 23篇 |
1999年 | 37篇 |
1998年 | 40篇 |
1997年 | 33篇 |
1996年 | 24篇 |
1995年 | 17篇 |
1994年 | 18篇 |
1993年 | 17篇 |
1992年 | 10篇 |
1991年 | 9篇 |
1990年 | 9篇 |
1989年 | 16篇 |
1988年 | 8篇 |
1987年 | 5篇 |
1986年 | 14篇 |
1985年 | 8篇 |
1984年 | 11篇 |
1983年 | 3篇 |
1982年 | 8篇 |
1981年 | 6篇 |
1980年 | 5篇 |
1979年 | 2篇 |
1977年 | 2篇 |
1976年 | 3篇 |
1973年 | 3篇 |
1965年 | 3篇 |
排序方式: 共有8964条查询结果,搜索用时 15 毫秒
81.
82.
83.
84.
85.
86.
Sonia Silvestrin Clécio Homrich da Silva Vânia Naomi Hirakata André A.S. Goldani Patrícia P. Silveira Marcelo Z. Goldani 《Jornal de pediatria》2013,89(4):339-345
ObjectiveTo assess the association between maternal education level and birth weight, considering the circumstances in which the excess use of technology in healthcare, as well as the scarcity of these resources, may result in similar outcomes.MethodsA meta-analysis of cohort and cross-sectional studies was performed; the studies were selected by systematic review in the MEDLINE database using the following Key**words socioeconomic factors, infant, low birth weight, cohort studies, cross-sectional studies. The summary measures of effect were obtained by random effect model, and its results were obtained through forest plot graphs. The publication bias was assessed by Egger's test, and the Newcastle-Ottawa scale was used to assess study quality.ResultsThe initial search found 729 articles. Of these, 594 were excluded after reading the title and abstract; 21, after consensus meetings among the three reviewers; 102, after reading the full text; and three for not having the proper outcome. Of the nine final articles, 88.8% had quality ≥ six stars (Newcastle-Ottawa Scale), showing good quality studies. The heterogeneity of the articles was considered moderate. High maternal education showed a 33% protective effect against low birth weight, whereas medium degree of education showed no significant protection when compared to low maternal education.ConclusionsThe hypothesis of similarity between the extreme degrees of social distribution, translated by maternal education level in relation to the proportion of low birth weight, was not confirmed. 相似文献
87.
88.
89.
90.
Yasmin R. Mohseni Adeel Saleem Sim L. Tung Caroline Dudreuilh Cameron Lang Qi Peng Alessia Volpe George Adigbli Amy Cross Joanna Hester Farzin Farzaneh Cristiano Scotta Robert I. Lechler Fadi Issa Gilbert O. Fruhwirth Giovanna Lombardi 《European journal of immunology》2021,51(10):2522-2530
Clinical trials of Treg therapy in transplantation are currently entering phases IIa and IIb, with the majority of these employing polyclonal Treg populations that harbor a broad specificity. Enhancing Treg specificity is possible with the use of chimeric antigen receptors (CARs), which can be customized to respond to a specific human leukocyte antigen (HLA). In this study, we build on our previous work in the development of HLA-A2 CAR-Tregs by further equipping cells with the constitutive expression of interleukin 10 (IL-10) and an imaging reporter as additional payloads. Cells were engineered to express combinations of these domains and assessed for phenotype and function. Cells expressing the full construct maintained a stable phenotype after transduction, were specifically activated by HLA-A2, and suppressed alloresponses potently. The addition of IL-10 provided an additional advantage to suppressive capacity. This study therefore provides an important proof-of-principle for this cell engineering approach for next-generation Treg therapy in transplantation. 相似文献