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“Real‐World” Comparison of Prasugrel With Ticagrelor in Patients With Acute Coronary Syndrome Treated With Percutaneous Coronary Intervention in the United States 下载免费PDF全文
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Laura Ashley PhD Claire Surr PhD Rachael Kelley RMN PhD Mollie Price PhD Alys Wyn Griffiths PhD Nicole R. Fowler MHSA PhD Dana E. Giza MD Richard D. Neal MBChB FRCGP PhD Charlene Martin PhD Jane B. Hopkinson RGN PhD Anita O’Donovan PhD William Dale MD PhD Bogda Koczwara BMBS MBioethics Katie Spencer MB BChir FRCR PhD Lynda Wyld MBChB FRCS PhD 《CA: a cancer journal for clinicians》2023,73(3):320-338
As many countries experience population aging, patients with cancer are becoming older and have more preexisting comorbidities, which include prevalent, age-related, chronic conditions such as dementia. People living with dementia (PLWD) are vulnerable to health disparities, and dementia has high potential to complicate and adversely affect care and outcomes across the cancer trajectory. This report offers an overview of dementia and its prevalence among patients with cancer and a summary of the research literature examining cancer care for PLWD. The reviewed research indicates that PLWD are more likely to have cancer diagnosed at an advanced stage, receive no or less extensive cancer treatment, and have poorer survival after a cancer diagnosis. These cancer disparities do not necessarily signify inappropriately later diagnosis or lower treatment of people with dementia as a group, and they are arguably less feasible and appropriate targets for care optimization. The reviewed research indicates that PLWD also have an increased risk of cancer-related emergency presentations, lower quality processes of cancer-related decision making, accessibility-related barriers to cancer investigations and treatment, higher experienced treatment burden and higher caregiver burden for families, and undertreated cancer-related pain. The authors propose that optimal cancer care for PLWD should focus on proactively minimizing these risk areas and thus must be highly person-centered, with holistic decision making, individualized reasonable adjustments to practice, and strong inclusion and support of family carers. Comprehensive recommendations are made for clinical practice and future research to help clinicians and providers deliver best and equitable cancer care for PLWD and their families. 相似文献
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Robert J. Grant MD Mary Ann Gregor MHSA Paul W. Beck MD Ronald F. Maio DO MS 《Academic emergency medicine》2000,7(8):892-897
OBJECTIVE: To determine the accuracy of police reports (PRs), ambulance reports (ARs), and emergency department records (EDRs) in describing motor vehicle crash (MVC) characteristics when compared with an investigation performed by an experienced crash investigator trained in impact biomechanics. METHODS: This was a cross-sectional, observational study. Ninety-one patients transported by ambulance to a university emergency department (ED) directly from the scene of an MVC from August 1997 to April 1998 were enrolled. Potential patients were identified from the ED log and consent was obtained to investigate the crash vehicle. Data describing MVC characteristics were abstracted from the PR, AR, and medical record. Variables of interest included restraint use (RU), air bag deployment (AD), and type of impact (TI). Agreements between the variables and the independent crash investigation were compared using kappa. Interrater reliability was determined using kappa by comparing a random sample of 20 abstracted reports for each data source with the originally abstracted data. RESULTS: Agreement using kappa between the crash investigation and each data source was 0.588 (95% CI = 0.508 to 0.667) for the PR, 0.330 (95% CI = 0.252 to 0.407) for the AR, and 0.492 (95% CI = 0.413 to 0.572) for the EDR. Variable agreement was 0.239 (95% CI = 0.164 to 0.314) for RU, 0.350 (95% CI = 0.268 to 0.432) for AD, and 0.631 (95% = 0.563 to 0.698) for TI. Interrater reliability was excellent (kappa > 0.8) for all data sources. CONCLUSIONS: The strength of the agreement between the independent crash investigation and the data sources that were measured by kappa was fair to moderate, indicating inaccuracies. This presents ramifications for researchers and necessitates consideration of the validity and accuracy of crash characteristics contained in these data sources. 相似文献
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Current status of home blood pressure monitoring in Asia: Statement from the HOPE Asia Network 下载免费PDF全文
Yook‐Chin Chia MBBS FRCP Peera Buranakitjaroen MD MSc DPhil Chen‐Huan Chen MD Romeo Divinagracia MD MHSA Satoshi Hoshide MD PhD Sungha Park MD PhD Jinho Shin MD Saulat Siddique MBBS MRCP FRCP Jorge Sison MD Arieska Ann Soenarta MD Guru Prasad Sogunuru MD DM Jam Chin Tay MBBS FAMS Yuda Turana MD PhD Ji‐Guang Wang MD PhD Lawrence Wong MD Yuqing Zhang MD Kazuomi Kario MD PhD On behalf of the HOPE Asia Network 《Journal of clinical hypertension (Greenwich, Conn.)》2017,19(11):1192-1201
Hypertension represents a major burden in Asia, with a high prevalence rate but poor level of awareness and control reported in many countries in the region. Home blood pressure monitoring has been validated as an accurate and reliable measure of blood pressure that can help guide hypertension treatment as well as identify masked and white‐coat hypertension. Despite its benefits, there has been limited research into home blood pressure monitoring in Asia. The authors reviewed the current evidence on home blood pressure monitoring in Asia, including but not limited to published literature, data presented at congresses, and national hypertension management guidelines to determine the current utilization of home blood pressure monitoring in clinical practice in the region. Public policies to enable greater access to home blood pressure monitoring and its use in clinical care would add considerably to improving hypertension outcomes in Asia. 相似文献
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Racial and Ethnic Differences in Initiation and Discontinuation of Antidementia Drugs by Medicare Beneficiaries 下载免费PDF全文
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Letters to the Editor 总被引:1,自引:0,他引:1
Keith E. Heller DDS DrPH ; Stephen A. Eklund DDS MHSA ; Brian A. Burt BDS MPH PhD 《Journal of public health dentistry》1998,58(3):199-199
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