Two dose Augmentin treatment of acute gonorrhoea in men.

We studied 192 men with acute gonococcal urethritis, 97 of whom received two oral doses of Augmentin (amoxycillin 3 g and clavulanic acid 250 mg) separated by a four hour interval; the remaining 95 received 2 g kanamycin in a single intramuscular injection. Of the patients treated with Augmentin, 93 (95.9%) were cured, which was significantly more than the 83 (87.4%) patients treated with kanamycin. Augmentin was equally effective in the treatment of penicillinase producing Neisseria gonorrhoeae (PPNG) and non-PPNG infections, the cure rates for which were 96.6% and 95.6% respectively.     

护士品质的伦理诠释

结合临床工作体会，从伦理学的角度探讨护士的品质，结合科尔伯格的道德发展阶段论，认为在护理工作中护士应紧跟护理学发展的需要，适应新时期的工作要求，具备良好的素质，培养自己多方面的工作能力，使护理工作更加人性化、规范化。     

The mechanism of diarrhoea resulting from pelvic and abdominal radiotherapy; a prospective study using selenium-75 labelled conjugated bile acid and cobalt-58 labelled cyanocobalamin

An attempt was made to elucidate the mechanism of diarrhoea resulting from pelvic and abdominal radiotherapy in a prospective study of 10 patients undergoing treatment for curable pelvic malignant tumours using the synthetic trihydroxy 75Se-labelled conjugated bile acid, SeHcat and 58Co-labelled cyanocobalamin (58Co Vit B12). Evidence of malabsorption of vitamin B12 measured as a significant fall in whole body percentage retention of 58Co Vit B12 from baseline levels was found in all nine patients who developed diarrhoea during radiotherapy. Only four out of these nine patients also had malabsorption of the trihydroxy conjugated bile acid, cholic acid, measured as a significant fall in SeHcat whole body percentage retention and these patients had the most severe diarrhoea. The findings are discussed in the light of what is known about the pathophysiology of diarrhoea during pelvic and abdominal radiotherapy and lend support to previous work which implicated increased bowel motility in the pathogenesis of radiation-induced diarrhoea. The hypothesis that local neuroendocrine mechanisms in the gut may be involved is put forward, with possible implications for treatment.     

Cytomegalovirus Mononucleosis in Chinese Infants

Two Chinese infants had cytomegalovirus inclusion disease presenting as persistent pneumonia and thrombocytopenic purpura, respectively. Both had lymphadenopathy, hepatosplenomegaly, pneumonia, and more than 14% atypical lymphocytes in the peripheral blood at some stage of the disease. The Paul-Bunnell reactions were serially negative. A clinical picture simulating infectious mononucleosis, including the presence of a high percentage of atypical lymphocytes in the peripheral blood, but serially negative Paul-Bunnell reactions, may be one of the many manifestations of cytomegalovirus inclusion disease in infancy and childhood.     

Esophagocolic anastomotic stricture repaired twelve years after original interposition.

Successful resection of a long, tight, unyielding cervical esophagocolic anastomosis with mobilization of the colon interposition transplant through a sternal splitting incision 12 years after the primary surgery is reported. The colon transplant with its vascular bundle was dissected with less difficulty than expected and 5 cm of increased length was obtained to make a new neck anastomosis without tension.