全文获取类型
收费全文 | 661869篇 |
免费 | 308094篇 |
国内免费 | 61885篇 |
专业分类
耳鼻咽喉 | 5698篇 |
儿科学 | 9549篇 |
妇产科学 | 7013篇 |
基础医学 | 135229篇 |
口腔科学 | 9474篇 |
临床医学 | 117731篇 |
内科学 | 149685篇 |
皮肤病学 | 9317篇 |
神经病学 | 40823篇 |
特种医学 | 23537篇 |
外国民族医学 | 264篇 |
外科学 | 78863篇 |
综合类 | 128680篇 |
现状与发展 | 109篇 |
一般理论 | 36篇 |
预防医学 | 70437篇 |
眼科学 | 27106篇 |
药学 | 100593篇 |
487篇 | |
中国医学 | 69439篇 |
肿瘤学 | 47778篇 |
出版年
2023年 | 8195篇 |
2022年 | 19205篇 |
2021年 | 23637篇 |
2020年 | 21520篇 |
2019年 | 25230篇 |
2018年 | 26189篇 |
2017年 | 26397篇 |
2016年 | 23944篇 |
2015年 | 30566篇 |
2014年 | 34735篇 |
2013年 | 32769篇 |
2012年 | 43541篇 |
2011年 | 48797篇 |
2010年 | 39416篇 |
2009年 | 42811篇 |
2008年 | 35038篇 |
2007年 | 32092篇 |
2006年 | 30766篇 |
2005年 | 30047篇 |
2004年 | 24059篇 |
2003年 | 22631篇 |
2002年 | 20525篇 |
2001年 | 20909篇 |
2000年 | 16535篇 |
1999年 | 21979篇 |
1998年 | 19824篇 |
1997年 | 19391篇 |
1996年 | 19122篇 |
1995年 | 18963篇 |
1994年 | 18116篇 |
1993年 | 15633篇 |
1992年 | 15512篇 |
1991年 | 14403篇 |
1990年 | 13110篇 |
1989年 | 12634篇 |
1988年 | 11870篇 |
1987年 | 11172篇 |
1986年 | 10437篇 |
1985年 | 9222篇 |
1984年 | 6946篇 |
1983年 | 6858篇 |
1982年 | 7760篇 |
1981年 | 7278篇 |
1980年 | 6897篇 |
1979年 | 6788篇 |
1978年 | 5880篇 |
1977年 | 6161篇 |
1976年 | 5770篇 |
1975年 | 5510篇 |
1974年 | 5072篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
51.
52.
53.
Background
HSVtk/ganciclovir (GCV) gene therapy has been extensively studied in tumors and relies largely on the gene expression of HSVtk. Most studies, however, have failed to demonstrate any significant benefit of a controlled gene expression strategy in cancer treatment. The Tet-On system is commonly used to regulate gene expression following Dox induction. We have evaluated the antitumor effect of HSVtk/ganciclovir gene therapy under Tet-On regulation by means of adeno-associated virus-2 (AAV-2)-mediated HSVtk gene transfer with direct intratumoral injections in mice bearing breast cancer tumors. 相似文献54.
经皮激光椎间盘减压术治疗椎间盘源性腰痛 总被引:1,自引:0,他引:1
目的探讨经皮激光椎间盘减压术(percutaneous laser disc decompression,PLDD)治疗椎间盘源性腰痛的疗效。方法2002年6月~2004年12月我院对36例椎间盘源性腰痛,采用英国DIOMED公司半导体激光仪,激光功率15W,每个激光脉冲持续1s,间隔1s,照射能量800~1200J。VAS评分评价治疗效果。结果手术时间15~60min,平均30min。32例出现“疼痛复制效应”。36例随访6~36个月,平均11个月,32例有效(术后VAS评分改善≥3分18例,≥分14例),4例无效,有效率88.9%(32/36)。结论PLDD治疗椎间盘源性腰痛安全、有效、微创。 相似文献
55.
56.
Vincent Chung Liang Liu Zhaoxiang Bian Zhongzhen Zhao Wai Leuk Fong Wan Fung Kum Jing Gao Min Li 《Movement disorders》2006,21(10):1709-1715
The objective of this study is to assess the efficacy and safety of herbal medicines (HMs), as a monotherapy or adjunct therapy, compared to placebo or conventional approaches in the treatment of idiopathic Parkinson's disease (PD). We conducted a systematic review of randomized controlled trials from both conventional and alternative medicine sources. Outcome measures were overall improvement, quality of life, reduction of levodopa dose, and adverse events. Nine studies were included, each testing a different HM. Six of the trials had limited internal validity due to major flaws in design, including the lack of proper randomization; insufficient blinding; unclear inclusive criteria in terms of diagnostic criteria, baseline staging, and duration of disease; lack of proper sample size calculation; and insufficient data analysis. Imbalances in gender and ethnicity among the patients in the included trials were observed. No major adverse events emerged, and no specific pattern was detected from the trials describing such data. In addition to major methodological defects, heterogeneity in (1) HM tested, (2) control treatment, and (3) outcome measure hindered in-depth data analysis and synthesis. Current evidence is insufficient to evaluate the efficacy and safety of various HMs. Further studies with improved trial design and reporting, with assessment on cost-effectiveness, quality of life, and qualitative data are warranted. 相似文献
57.
李联崑 《中国实用妇科与产科杂志》2006,22(8):582-583
放射治疗在杀死肿瘤细胞的同时,对肿瘤周围器官的细胞和组织也有杀伤作用,从而引起近期放疗反应和远期并发症。 相似文献
58.
慢性萎缩性胃炎是以胃黏膜上皮和腺体萎缩、黏膜变薄为特征的慢性疾病。属中医胃脘痛、胃痞等范畴。其病因病机较为复杂,多与饮食不调、情志不畅有关,尤其是饮酒、过食刺激之品,致使脾胃受损,阳气郁遏不振,纳运失司,化源不足,气血阴液亏乏;或中焦运化无力,湿邪滞塞,郁而化热;或 相似文献
59.
PURPOSE: The aim of this study was to determine the reproducibility of measurements made using the Sonogage Corneo-Gage Plus 2 (Cleveland, Ohio) ultrasound pachymeter of total corneal and corneal epithelial thickness in 5 different regions of the cornea. METHODS: Twenty-seven subjects at the New England College of Optometry (NECO) and 20 subjects at the Southern College of Optometry (SCO) were enrolled in this study. Measurements were taken of the central cornea as well as the nasal and temporal regions of the midperipheral and peripheral regions of the right cornea of each subject. Identical measurements were again taken in these subjects 1 week later at approximately the same time of day. Within-subject variations were then assessed using paired t tests. RESULTS: The only significant measurement differences that were found between visits were for full corneal thickness at both the nasal and temporal midperipheral locations. The mean differences for these locations were 13.5 microm and 13.7 microm, respectively. CONCLUSIONS: Epithelial corneal thickness and central and peripheral total corneal thickness measurements using the Corneo-Gage Plus 2 pachymeter were reproducible; however, midperipheral total corneal thickness measurements showed poor reproducibility. 相似文献
60.