视力低下局限性脉络膜血管瘤的临床治疗

目的:描述第三级转诊中心15a期间局限性脉络膜血管瘤(CCH)患者光动力疗法的临床经验。方法:对1992/2007年第三级转诊中心确诊(基本数据和摄影记录为主要确诊依据)为局限性脉络膜血管瘤患者进行记录。结果:患者11例(69%)视力改善(>2行),1例(5%)患者视力保持稳定,4例(25%)患者恶化。6/7患者采用放疗的方法和3/4采用瞳孔温热疗法治疗均获得了良好的效果。86%的患者发病6mo内进行治疗和50%的患者发病6mo后进行治疗视力有明显的改善。只有一个患者视力<6/60。平均随访时间为35mo。结论:发病6mo内进行治疗的患者效果较好。多数患者经过治疗后视力显著改善且无任何不良影响。     

Application of a disease-specific mapping function to estimate utility gains with effective treatment of schizophrenia

Background  

Most tools for estimating utilities use clinical trial data from general health status models, such as the 36-Item Short-Form Health Survey (SF-36). A disease-specific model may be more appropriate. The objective of this study was to apply a disease-specific utility mapping function for schizophrenia to data from a large, 1-year, open-label study of long-acting risperidone and to compare its performance with an SF-36-based utility mapping function.     

Functional and morphologic characteristics of the leukemic cells of a patient with acute monocytic leukemia: correlation with clinical features

The clinical course of a patient with acute monocytic leukemia and prominent infiltration of the skin and testes is described. In vitro studies demonstrated that the circulating monocyte precursors were capable of adherence to nylon fibers, and phagocytosis of bacteria and latex particles. In vivo, migration of leukemic cells to skin windows was observed. Extreme nuclear folding, marked surface activity, and morphologic features suggesting nuclear and cytoplasmic maturation were seen by light and electron microscopy. The presence of morphologically and functionally more differentiated monocytic cells may account for the marked tiuuse invasion in this patient and, possibly, in other patients with monocytic leukemia.     

Conducting an advance care planning group among older adults living in residential care homes: An initiative of social workers in Hong Kong

This study aimed to examine the effects of an advance care planning (ACP) group which was developed by social workers in Hong Kong for older adults. A quasi-experimental study was conducted. Participants were recruited from 14 residential care homes. The ACP intervention group included 59 participants for analyses, and the control group 58. Three major outcomes were measured at two time points: (a) Quality-of-life concerns, (b) End-of-life preference and (c) Advance directive (AD)-related outcomes (awareness of AD, AD completion, willingness to complete AD and communication with family members about AD). Findings indicate that the ACP group enhanced participants’ awareness of AD compared with the control group. Participants were also more willing to complete AD, and more participants communicated with family members about AD after participating in the ACP group. No significant difference was found in other outcomes. This study demonstrates the efforts of social workers in promoting ACP in Hong Kong and the effectiveness of an ACP group for enhancing older adults’ awareness of AD. Findings support the role of social workers in promoting ACP for deprived groups, like frail older adults. The ACP group could be considered a first step in enhancing older adults’ awareness of and willingness to discuss end-of-life issues. Further follow-up is required to develop individualised ACP for older adults.     

389例乳腺可疑病灶MR引导下真空活检的有效率、准确性

本研究通过与组织病理学对照研究,旨在评估MR引导下真空活检（10号针、9号针）诊断乳腺病变的有效率、准确性．这些可疑病灶仅在MRI上可见。365例MR乳腺成像发现乳腺可疑病灶患者共进行389次MR引导下真空活检（分别采用Vacora系统10号针、Bard公司或ATEC系统、9号针,