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51.
52.
Jardine C Appleyard G Kosoy MY McColl D Chirino-Trejo M Wobeser G Leighton FA 《Vector borne and zoonotic diseases (Larchmont, N.Y.)》2005,5(4):402-409
Six species of wild rodents were sampled at 10 sites in 2002 and 2003 to determine the prevalence of Bartonella infections in rodent communities near Saskatoon, Saskatchewan, Canada. Isolates were characterized genotypically and compared with isolates found at other locations. Of 104 wild rodents examined, 57% were infected with Bartonella and prevalence within species varied from 49% for Richardson's ground squirrels (Spermophilus richardsonii) to 90% for Franklin's ground squirrels (S. franklinii). Infected rodents were found at all sites. Sequencing of a 379-bp portion of the citrate synthase gene was performed on 54 isolates and revealed 13 distinct genotypes, eight of which had not been described previously. The most common genotype detected in red-backed voles (Clethrionomys gapperi) was 99.1% similar to B. grahamii, a known human pathogen. Two of 10 Franklin's ground squirrels were concurrently infected with multiple Bartonella genotypes. All genotypes, with the exception of one detected in both Franklin's and thirteen-lined ground squirrels (S. tridecemlineatus), were found in only one host, and all genotypes from each species, with the exception of genotypes detected in red-backed voles, clustered together within the same relatedness group, suggesting that at least some Bartonella genotypes are specific to some rodent hosts. 相似文献
53.
Bartonella strains from ground squirrels are identical to Bartonella washoensis isolated from a human patient 总被引:8,自引:0,他引:8
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The most likely animal source of a human case of cardiac disease in Washoe County, Nev., was identified by comparison of DNA sequences of three genes (citrate synthase gltA, 60-kDa heat shock protein gene groEL, and 16S rRNA gene) of Bartonella washoensis cultured from the human patient in question and of Bartonella isolates obtained from the following Nevada rodents: Peromyscus maniculatus (17 isolates), Tamias minimus (11 isolates), Spermophilus lateralis (3 isolates), and Spermophilus beecheyi (7 isolates). Sequence analyses of gltA amplicons obtained from Bartonella from the rodents demonstrated considerable heterogeneity and resulted in the identification of 16 genetic variants that were clustered within three groups in phylogenetic analysis. Each of the three groups was associated with a rodent genus, Peromyscus, Tamias, or Spermophilus: The gltA, 16S rRNA gene, and groEL sequences of a Bartonella isolate obtained from a California ground squirrel (S. beecheyi) were completely identical to homologous sequences of B. washoensis, strongly suggesting that these animals were the source of infection in the human case. 相似文献
54.
Mayte Suárez-Fariñas Minami Tokuyama Gabrielle Wei Ruiqi Huang Alexandra Livanos Divya Jha Anais Levescot Haritz Irizar Roman Kosoy Sascha Cording Wenhui Wang Bojan Losic Ryan C. Ungaro Antonio Di’Narzo Gustavo Martinez-Delgado Maria Suprun Michael J. Corley Aleksandar Stojmirovic Saurabh Mehandru 《Gastroenterology》2021,160(1):287-301.e20
55.
56.
Rebecca E. Colman Amy J. Vogler Jennifer L. Lowell Kenneth L. Gage Christina Morway Pamela J. Reynolds Paul Ettestad Paul Keim Michael Y. Kosoy David M. Wagner 《Emerging infectious diseases》2009,15(10):1623-1625
We describe an analytic approach to provide fine-scale discrimination among multiple infection source hypotheses. This approach uses mutation-rate data for rapidly evolving multiple locus variable-number tandem repeat loci in probabilistic models to identify the most likely source. We illustrate the utility of this approach using data from a North American human plague investigation. 相似文献
57.
Hao Li Wei Liu Guang-Zhou Zhang Zhao-Zeng Sun Jie-Ying Bai Bao-Gui Jiang Yao-Yun Zhang Xiao-Guang Zhao Hong Yang Guang Tian Yu-Chuan Li Lin Zeng Michael Kosoy Wu-Chun Cao 《Emerging infectious diseases》2013,19(2):297-300
We detected Bartonella quintana in 48.6% of captive rhesus macaques from an animal facility in Beijing, China. Prevalence of infection increased over the period of observation. Our findings suggest that macaques may serve as reservoir hosts for B. quintana and that Pedicinus obtusus lice might act as efficient vectors. 相似文献
58.
Billeter SA Cáceres AG Gonzales-Hidalgo J Luna-Caypo D Kosoy MY 《Journal of medical entomology》2011,48(6):1257-1260
A total of 103 ticks, collected from canines, horses, donkeys, and snakes from Peru, were screened for the presence of Bartonella DNA by polymerase chain reaction analysis. Bartonella DNA was detected in two ticks using Bartonella 16S-23S intergenic spacer region primers and in an additional two ticks using Bartonella NADH dehydrogenase gamma subunit gene (nuoG) primers. Bartonella rochalimae Eremeeva et al., B. quintana Schmincke, and B. elizabethae Daly et al. DNA was detected in a Rhipicephalus sanguineus Latreille (Acari: Ixodidae) female tick removed from a dog and B. quintana DNA was present in a Dermacentor nitens Neumann (Acari: Ixodidae) pool of five larvae, one nymph, and one adult male tick collected from donkeys. This is the first study to report the detection of B. rochalimae, B. quintana, and B. elizabethae DNA in ticks from Peru. Further investigations must be performed to decipher the role ticks may play in the transmission of Bartonella species. 相似文献
59.
Matthew A. Hevey Jane A. O'Halloran Brett W. Jagger Jennifer E. Staples Amy J. Lambert Amanda J. Panella Olga I. Kosoy George Turabelidze David S. Raymer Gregory A. Ewald Jennie H. Kwon 《Transplant infectious disease》2019,21(4)
Tick‐borne infections represent a significant health risk each year in the United States. Immunocompromised patients are typically at risk of more severe disease manifestations than their immunocompetent counterparts. Here we report a case of a newly emerging phlebovirus, Heartland virus, in a heart transplant recipient. 相似文献
60.
Laudisoit A Iverson J Neerinckx S Shako JC Nsabimana JM Kersh G Kosoy M Zeidner N 《Asian Pacific journal of tropical medicine》2011,4(4):320-322
ObjectiveTo assess the presence and identity of Bartonella species in a pool of human blood samples from DRC Congo.MethodsBlood (±120μL) was collected anonymously from Congolese patients and placed on calibrated filter papers. Bartonella serology determination was performed using an indirect immunofluorescence assay (IFA) against six specific Bartonella antigens and Coxiella burnetii (C. burnetii) antigen. The end cut-off value for Bartonella sp. was a titre greater than 1:200.ResultsNone of the patients was positive for Bartonella elizabethae, Bartonella vinsonii subsp. vinsonii or Bartonella vinsonii subsp. arupensis nor for C. burnetti, but 4.5% of the 155 samples were positive for either Bartonella henselae, Bartonella quintana, or Bartonella clarridgeiae.ConclusionsThis preliminary study presents the first report of Bartonella species in the DR Congo and the first report of antibodies to Bartonella clarridgeiae in an African human population. Although few experimental trials have established the link between fleas and Bartonella transmission, the repeated detection of similar Bartonella species in fleas and humans in several countries suggests that Bartonellosis could be another flea-borne disease which specific reservoirs are still unknown. 相似文献