全文获取类型
收费全文 | 406篇 |
免费 | 18篇 |
国内免费 | 16篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 17篇 |
妇产科学 | 6篇 |
基础医学 | 56篇 |
口腔科学 | 5篇 |
临床医学 | 49篇 |
内科学 | 82篇 |
皮肤病学 | 10篇 |
神经病学 | 5篇 |
特种医学 | 69篇 |
外科学 | 10篇 |
综合类 | 8篇 |
预防医学 | 41篇 |
眼科学 | 3篇 |
药学 | 51篇 |
肿瘤学 | 19篇 |
出版年
2023年 | 2篇 |
2020年 | 3篇 |
2018年 | 3篇 |
2017年 | 2篇 |
2016年 | 3篇 |
2015年 | 7篇 |
2014年 | 7篇 |
2013年 | 8篇 |
2012年 | 6篇 |
2011年 | 15篇 |
2010年 | 7篇 |
2009年 | 10篇 |
2008年 | 7篇 |
2007年 | 28篇 |
2006年 | 3篇 |
2005年 | 8篇 |
2004年 | 7篇 |
2003年 | 8篇 |
2002年 | 8篇 |
2001年 | 11篇 |
2000年 | 11篇 |
1999年 | 11篇 |
1998年 | 17篇 |
1997年 | 21篇 |
1996年 | 22篇 |
1995年 | 18篇 |
1994年 | 15篇 |
1993年 | 12篇 |
1992年 | 6篇 |
1991年 | 3篇 |
1990年 | 14篇 |
1989年 | 24篇 |
1988年 | 16篇 |
1987年 | 18篇 |
1986年 | 9篇 |
1985年 | 12篇 |
1983年 | 7篇 |
1982年 | 10篇 |
1981年 | 7篇 |
1979年 | 4篇 |
1978年 | 3篇 |
1977年 | 4篇 |
1976年 | 3篇 |
1975年 | 9篇 |
1972年 | 1篇 |
1971年 | 1篇 |
1969年 | 1篇 |
1968年 | 1篇 |
1967年 | 1篇 |
1959年 | 1篇 |
排序方式: 共有440条查询结果,搜索用时 15 毫秒
101.
Damenia AO Turkevich EA Semiglazov VF Kochetova IA Gurbanov SS Bit-Sava EM Efimenko AV 《Voprosy onkologii》2007,53(6):674-676
The study was concerned with biological features of inoperable breast cancer and their prognostic significance for patients under 35. That age was identified as a prognosticator for breast cancer: high-grade (G3) malignancies, vascular invasion and EIC+component were relatively more frequent in such patients. Also, those with HER2/neu hyperexpression had worst prognosis. 相似文献
102.
Evaluation of the chronic toxicity and oncogenicity of N,N-diethyl-m- toluamide (DEET) 总被引:1,自引:0,他引:1
Schoenig GP; Osimitz TG; Gabriel KL; Hartnagel R; Gill MW; Goldenthal EI 《Toxicological sciences》1999,47(1):99-109
Chronic toxicity and/or oncogenicity studies were conducted in rats, mice,
and dogs with the insect repellent DEET. DEET was mixed in the diet and
administered to CD rats for two years at concentrations that corresponded
to dosage levels of 10, 30 or 100 mg/kg/day for males and 30, 100, or 400
mg/kg/day for females; to CD-1 mice for 18 months at dosage levels of 250,
500, or 1000 mg/kg/day; and to dogs for one year, via gelatin capsules, at
dosage levels of 30, 100, or 400 mg/kg/day. In the rodent studies, each
group consisted of 60 animals of each sex, and two concurrent independent
control groups, each containing 60 animals/sex were included in each study.
Each group in the dog study consisted of four male and four female dogs and
one control group was included in the study. Treatment-related effects were
observed at the highest dose level in all three studies. For rats, the
effects included decreases in body weight and food consumption and an
increase in serum cholesterol in females only. In mice, the effects
observed were decreases in body weight and food consumption in both sexes.
The effects observed in dogs included increased incidences of emesis and
ptyalism, and levels of transient reduction in hemoglobin and hematocrit,
increased alkaline phosphatase (males only), decreased cholesterol, and
increased potassium. One male dog in the high-dose group also exhibited
ataxia, tremors, abnormal head movements, and/or convulsions on several
occasions during the study. The highest no- observed-effect levels (NO-ELs)
for rats, mice and dogs were determined to be 100, 500, and 100 mg/kg/day,
respectively. No specific target organ toxicity or oncogenicity was
observed in any of the studies.
相似文献
103.
Based on State Medical Statistics, dynamics of the technical supply of the medical diagnostic service of the Russian Federation in 2002-2010, including X-ray diagnosis and endoscopy, is discussed. 相似文献
104.
105.
106.
107.
T. S. Zakharova E. S. Fortinskaya M. M. Kochetova I. Sh. Babakhanov T. I. Torkhovskaya E. M. Khalilov 《Bulletin of experimental biology and medicine》2000,129(2):144-145
Using the methods of surface balance we compared the effects of different phosphatidylcholines and synthetic surfactant Exosurf
on the equilibrium surface tension at the air-water interface. It was found that dipalmitoyl-lecithin, the principal component
of natural surfactant, and its synthetic substitutes can be replaced by other phosphatidylcholines, in particular, by modified
soybean phosphatidylcholine phospholipon. It was demonstrated that equilibrium surface tension is an informative characteristic
in the assessment of potential components for synthetic surfactants.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 2, pp. 168–170, February, 2000 相似文献
108.
OBJECTIVE: To assess whether physical growth is affected in early treated Dutch patients with phenylketonuria (PKU). METHODS: The birth weights of all 137 early detected patients with PKU born in the period from 1974 to 1988 in the Netherlands were compared with reference values. Height, head circumference, and weight were measured at the age at which treatment started (commonly about 2-3 weeks), at 6 months of age, and yearly from the child's first birthday up to the age of 10 years. These measurements were compared with reference values. RESULTS: The adjusted birth weight in patients with PKU was 141 g (95% confidence interval (CI) 66 to 216 g) less than Dutch reference values by Kloosterman and 103 g (95% CI 9 to 196 g) less compared with the birth weight of another reference group. At the age at which treatment started, z scores of patients for height by age were -0.23 (95% CI -0.44 to -0.02) and z scores for head circumference by the age were -0.25 (95% CI -0.44 to -0.06). From the age at which treatment started up to the age of 3 years z scores for height by age further decreased to -0.74 (95% confidence interval -0.93 to -0.56), after which no additional decrease occurred. In contrast, z scores for head circumference increased from -0.25 at the first visit to 0.08 (95% CI -0.14 to 0.30) at the age of 1 year, after which they remained close to zero. Weight by height was close to the expected centiles for all ages. CONCLUSION: Patients with PKU are growth retarded at birth and have smaller head circumferences than the normal population. In Dutch patients further growth retardation occurs in the first three years of life. 相似文献
109.
MM Latham GP Smart B Hedland-Thomas CS Harper 《Journal of Medical Imaging and Radiation Oncology》1997,41(4):357-360
Early-stage squamous cell carcinoma of the larynx is usually treated with local field radiotherapy. Surgery is used for salvage following recurrence. Further recurrences present a more difficult therapeutic problem which requires individualized management. The aims of local control, survival, maintenance of function and minimizing side effects all need to be balanced according to the site and extent of disease. The present case study looks at the management of a 54-year-old man with multiple recurrences from a squamous cell carcinoma of the larynx. It describes a technique of endoluminal brachytherapy using an iridium-192 wire spiralled around the outer part of a tracheostomy tube that achieves good local control while enabling self-insertion and self-cleaning during the procedure. The dose given was 2500 cGy at 5 mm over 25.2 h and was achieved with minimal early or delayed side effects. The patient had no further symptoms relating to the stomal recurrence until his death from metastatic disease 6 months later. 相似文献
110.
含巨菊形团的玻璃样变梭形细胞肿瘤 (HSCTGR)是近年来才被命名的间叶性肿瘤 ,光镜下类似低度恶性纤维粘液肉瘤。作者观察了 3例HSCTGR的光镜、电镜及免疫组化表现。3例中男性 2例 ,分别为 41和 5 4岁 ,女性 1例 ,6 2岁。肿瘤位于深部软组织 ,2例在下肢 ,1例在上臂。大体上 ,最大径 3~ 13 3cm不等 ,境界清楚 ,呈棕红色或黄白色 ,质实 ,可伴囊性变 ,其中发生于小腿的 1例合并有股骨骨肉瘤 ,小腿部肿块仅做了活检。光镜下 3例图像相似 ,均有纤维粘液样区 ,2例伴有玻璃样变 ,1例有灶性骨化。肿瘤细胞为温和的卵圆形至梭形细胞 ,… 相似文献